E-Dissertationen: Search
Now showing items 301-310 of 358
Knowledge Management approaches to model pathophysiological mechanisms and discover drug targets in Multiple Sclerosis
(2019-04-30)
Multiple Sclerosis (MS) is one of the most prevalent neurodegenerative diseases for which a cure is not yet available. MS is a complex disease for numerous reasons; its etiology is unknown, the diagnosis is not exclusive, ...
On some Geometric Search Problems: Algorithms, Complexity, Computability
(2020-11-25)
This thesis considers four search problems which are related to or emerge from a geometric context. Each search problem is examined in a separate chapter; these four chapters are framed by an introduction and a conclusion ...
Discovering lesser known molecular players and mechanistic patterns in Alzheimer's disease using an integrative disease modelling approach
(2018-12-13)
Convergence of exponentially advancing technologies is driving medical research with life changing discoveries. On the contrary, repeated failures of high-profile drugs to battle Alzheimer's disease (AD) has made it one ...
Collaborative Integration, Publishing and Analysis of Distributed Scholarly Metadata
(2019-02-25)
Research is becoming increasingly digital, interdisciplinary, and data-driven and affects different environments in addition to academia, such as industry, and government. Research output representation, publication, mining, ...
Bridging between data and knowledge: New ways to better understand Alzheimer's Disease and Type 2 Diabetes comorbidity
(2021-06-15)
The holistic understanding of biological phenomena enabled by systems biology forms the basis of current research. As opposed to the principle of classical biology where behavior of a biological system is explained by ...
How to Conduct Security Studies with Software Developers
(2022-07-13)
As our everyday life depends on software and its security, studies with software developers become ever more important. Motivated by multiple security breaches caused by issues during software development, more studies ...
Fast, Accurate and Steerable Segmentation of Drusen in Optical Coherence Tomography
(2020-10-05)
Age-related macular degeneration (AMD) is known to be the leading cause for blindness in developed countries. One of the early appearing biomarkers of AMD are drusen that develop between the retinal pigment epithelium (RPE) ...
Conversational Question Answering over Knowledge Graphs with Answer Verbalization
(2022-12-05)
In recent years, publicly available knowledge graphs (KG) have been broadly adopted as a source of knowledge in several tasks such as entity linking, relation extraction, and question answering. Question answering (QA) ...
On Modeling and Assessing Uncertainty Estimates in Neural Learning Systems
(2023-04-20)
While neural networks are universal function approximators when looked at from a theoretical perspective, we face, in practice, model size constraints and highly sparse data samples from open-world contexts. These limitations ......
Extracting and Exploiting Structure in Point Clouds for Editing and Interpolation
(2022-12-22)
Modern movies and computer games employ rich virtual environments to offer the consumer an immersive experience. Digital models are often easier and more cost-efficient to create than acquiring
real-world film footage ...