E-Dissertationen: Search
Now showing items 51-60 of 430
Structural aspects of the plasmalemmal Amyloid Precursor Protein cluster
(2021-11-12)
Alzheimer’s Disease (AD) is a major socio-economic threat to health care systems and society in general. Involvement of the amyloid-beta peptide (Aβ) and its parent, the amyloid precursor protein (APP), in AD seemed obvious ...
Quantenchemische Untersuchung der elektronischen Eigenschaften von Ferriten
(2021-06-21)
Die vorliegende Arbeit befasst sich mit der theoretischen Untersuchung der optischen und elektronischen Eigenschaften von Spinell-Ferriten MFe2O4 mit M = Mg, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn und ......
On Discrete and Geometric Firefighting
(2021-08-19)
Wildfires ravaging forests around the globe cost lives, homes and billions in damages every year, which motivates the study of effective firefighting. In the area of theoretical computer science, several different models ......
Design and Development of Depleted Monolithic Active Pixel Sensors with Small Collection Electrode for High-Radiation Applications
(2021-09-27)
Depleted monolithic active pixel sensors (DMAPS) have emerged as a low material and low cost alternative to the established hybrid technology. In this thesis, two large scale prototype chips that feature a fast column-drain ...
3D-Silicon and Passive CMOS Sensors for Pixel Detectors in High Radiation Environments
(2020-10-30)
The future upgrade of the Large Hadron Collider to the High-Luminosity LHC demands new pixel detectors that can operate in environments with exceptionally high radiation. This requires investigations into new radiation-tolerant ...
Development and Application of London Dispersion Corrections for Electronic Structure Methods
(2020-05-19)
Mean-field electronic structure methods like Hartree–Fock ( HF ) or Kohn–Sham ( KS ) Density Functional Theory ( DFT ) do not account for long-range correlation effects and consequently not for London Dispersion ......
Knowledge Context for Entity and Relation Linking
(2021-10-28)
Knowledge graphs (KGs) are structures that provide a compendious representation of real world facts about entities and their relationships. The last decade has seen an increase in the number, size and application of knowledge ...
Computation of Electronic Excitation Spectra of Large Biomolecular Systems
(2020-11-30)
This thesis presents the theoretical investigation of electronic excitation spectra and nonlinear responses of large biomolecular systems (e.g., proteins or deoxyribonucleic acid fragments), with a particular focus on the ...
Multi-View Kernel Methods for Binding Affinity Prediction
(2021-09-27)
In the present thesis, we focus on the potential and limits of multi-view regression techniques in the field of ligand affinity prediction.
Multi-view learning (MVL) denotes machine learning approaches that utilise ...
Multi-view learning (MVL) denotes machine learning approaches that utilise ...
Functional analysis of the endocannabinoid system in conditional mouse mutants
(2020-09-04)
In the scope of this thesis conditional knockout mice with a cell-specific deletion of Dagla (diacylglycerol lipase alpha) in neurons, astrocytes or microglia cells were generated, in order to identify the cellular source ...