E-Dissertationen: Search
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Untersuchungen zur Funktion der Fettsäure-2-Hydroxylase (FA2H) in der Haut- und Haarfollikel-Homöostase der Maus
(2012-07-18)
Die Fettsäure-2-Hydroxylase (FA2H) ist das einzige bisher bekannte Enzym, das die α-Hydroxylierung von unverzweigten Fettsäuren katalysiert. Letztere sind Bestandteile von α-hydroxylierten Sphingolipiden, die in der Haut ......
The homeodomain of the Drosophila Ceramide Synthase Schlank confers nuclear import information and DNA binding capabilities
(2014-05-15)
Ceramide Synthases (CerS) are membrane bound enzymes at the center of the sphingolipid synthesis cascade. A sub-class of CerS also codes for a homeodomain of unknown function.
We previously identified the ...
We previously identified the ...
Consequence of FA2H Deficiency and FA2H Interaction Partners Revealed by Proteomic Analyses
(2015-03-10)
Fatty acid-2 hydroxylase (FA2H) is a 43 kDa transmembrane protein residing in the endoplasmic reticulum. As a monooxygenase it is responsible for the alpha–hydroxylation of fatty acids, which are later incorporated into ...
Synthesis of ganglioside and lysoganglioside lipoforms as internal standards for MS quantification
(2015-01-08)
The goal of this work was to establish methods for the synthesis of modified gangliosides that are suitable as internal standards for mass spectrometry. Quantification of gangliosides is usually achieved by staining after ...