E-Dissertationen: Search
Now showing items 1-7 of 7
Pharmacokinetic / Pharmacodynamic Modeling and Simulation of Biomarker Response to Venlafaxine and Sunitinib Administration
(2011-03-23)
In this thesis the concept of pharmacokinetic/pharmacodynamic modeling using biomarkers for the description of concentration-effect relationships was illustrated on the example of two projects with drugs from different ...
Reaktionstechnische Untersuchungen zur enzymatischen de novo Synthese von GDP-β-L-Fucose und der in situ Fucosylierung von Oligosacchariden
(2005)
Eine Vielzahl inter- und intrazellul?rer Erkennungsprozesse basieren auf der Wechselwirkung von Oligosacchariden mit anderen (Makro-)Molek?len. Beispiele sind virale oder mikrobielle Infektionen, Entz?ndungsreaktionen und ...
Modellierung der aktiven Tastsensibilität natürlicher Zähne
(2005)
In der Zahnmedizin wird die feine Tastsensibilität natürlicher Zähne seit langem beschrieben. Hierzu durchgeführte Experimente dienten in erster Linie dazu, Schwellenwerte zu bestimmen. Die Modellierung der Tastsensibilität ...
Geomorphological Dating of Scarps in Temperate Climate Using a Modified Diffusion Model: in Temperate Climate Using a Modifed Diffusion Model
(2004)
Geomorphological dating of a certain landform or geomorphological structure is based on the evolution of the landscape itself. In this context it is difficult to use common absolute dating techniques because they require ...
From cell to robot: A bio-inspired locomotion device
(2014-05-02)
Bionics or biomimetics is an interdisciplinary research field, a scientific approach to applicate naturally developed biological systems, methods and solutions to the study and design of technology and engineering systems. ...
Application of Sensitive API-Based Indicators and Numerical Simulation Tools to Advance Hot-Melt Extrusion Process Understanding
(2019-09-11)
This dissertation explored the use of active pharmaceutical ingredients (APIs) as indicator substances as well as numerical process simulation to enhance process understanding of hot-melt extrusion (HME) in the pharmaceutical ......
Model-based formulation of amorphous solid dispersions made by hot-melt extrusion
(2019-08-21)
Regarding hot-melt extrusion in early pharmaceutical formulation and process development, techniques and procedures are needed to simplify the application of hot-melt extrusion (HME) and to decrease the effort in terms of ......