E-Dissertationen: Search
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Langerhans and inflammatory dendritic epidermal cells in atopic dermatitis tolerate Toll-like receptor 2-specific activation
(2021-01-26)
Atopic dermatitis (AD) is a chronic multifactorial inflammatory skin disease. The skin of AD patients shows a significant dysbalance of the microbiome with high colonization of S. aureus, which positively correlates with ...
Recognition of cytosolic 3´P DNA & The role of GCET2+ DCs in cross-presentation
(2020-04-01)
In mammalian cells, DNA is confined to the nucleus and mitochondria. Detection of DNA in other compartments like the cytoplasm indicates danger and infection. Our research group has previously discovered that 3´monophosphate ...
Elucidation of multinumerous centrosomes and their impact on migration in dendritic cells
(2023)
Centrosomes act as major microtubule organizing center (MTOC) in most animal cells and are well known for their role in building up the mitotic spindle during cell division. Core structure of the centrosome are two tubulus ...