The infinitesimal counterpart of a Lie group is its Lie algebra: the space of right-invariant vector fields with their Lie bracket. As a vector space, it is isomorphic to the tangent space to the Lie group at the unit. A ...

The onset of the COVID-19 pandemic in 2020 highlighted the urgent need for efficient navigation of big data. In response, numerous workflows and algorithms for data processing, aggregation, and analysis were developed and ...

Gene therapy has emerged as a promising approach for Hemophilia A and B, enabling sustained production of clotting factors and reducing reliance on frequent FVIII infusions. While Hemophilia B therapies targeting Factor ...

Squaraines are a class of dye molecules obtained through reaction of mostly electron-rich molecules with squaric acid. It is an intriguing class of molecules, which has a wide field of applications and seemingly endless ...

Lysolipin natural products are a family of bacterial polycyclic xanthones, renowned for their antibiotic potency and structural diversity. Yet, their complex architectures have long eluded synthetic access, and their ...

Plastic pollution has emerged as a global environmental crisis of unprecedented scale. Micro- and nanoplastic (MNP) pervade ecosystems, resulting in persistent exposure for all living organisms, including humans. MNP have ...

The mechanoresponse of epithelia is a well-known and essential process. Both cytoskeleton and cell adhesion sites react to mechanical stimuli, e.g. mechanical stretch. Cell adhesions like desmosomes act as connection sites ...

Neurodegenerative Disorders, including Alzheimer's, Parkinson's, and Huntington's Disease, pose major challenges to modern medicine due to their progressive nature and impact on patients and the healthcare system. These ...

Quantum Optimization (QO) is emerging as a promising approach to tackle hard combinatorial optimization problems by leveraging the unique computational properties of quantum hardware. In recent years, QO has gained traction ...

In dieser Dissertation wurden intrazelluläre bakterielle Erreger in Bezug auf deren Ausbreitung, antibiotische Therapie und Biologie untersucht. Der erste Teil der Arbeit befasste sich mit zoonotischen sowie neuartigen ...