E-Dissertationen: E-Dissertationen: Recent submissions
Now showing items 41-60 of 4162
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A story about difluoromethyl-1,3,4-oxadiazoles: Synthesis and biochemical evaluation of an enigmatic novel zinc binding group for the highly selective inhibition and degradation of histone deacetylase 6
König, Beate (2024-07-22)Histone deacetylase 6 (HDAC6) is a valuable pharmaceutical target in oncological and non-oncological diseases. Classical selective HDAC6 inhibitors utilize a hydroxamic acid as zinc binding group (ZBG), which is associated ... -
Stability of Solitary Waves for the nonlinear Schrödinger Equation
Ritschl, Tillman (2024-07-22)Consider the one-dimensional focusing nonlinear Schrödinger equation with subcritical/critical exponent. <br /> This thesis examines a question derived from the so-called soliton resolution conjecture. The NLS admits ... -
Role of the CCL17/CCL22-CCR4-axis in the barrier organs skin and gut
Gottschalk, Marlene (2024-07-18)(noch nicht zugänglich / not yet accessible) -
Towards a systematic study of {D1,D2}-{D,D*} scattering and exotic vector states
von Detten, Leon Alexander (2024-07-18)As one of the four known fundamental forces in nature, the strong interaction is crucial for the formation of matter. Established in the early 1970s, the underlying field theory of quantum chromodynamics is embedded in our ... -
Testing large scale cosmology with MeerKAT
Wagenveld, Jonah Daniël (2024-07-17)The cosmic radio dipole is an anisotropy in the number counts of radio sources, analogous to the dipole seen in the cosmic microwave background (CMB). Measurements of the radio dipole with large radio surveys have shown ... -
Sunyaev-Zeldovich power spectrum measurements predictions for upcoming ground-based telescopes
Charmetant, Maude (2024-07-17)This work aimed to assess the detectability of the Sunyaev-Zeldovich (SZ) effects for upcoming highresolution ground-based telescopes such as the Simons Observatory (SO) and Fred Young Submillimeter Telescope (FYST). SZ ... -
A census on the gas content of star-forming galaxies over the past 11 billion years of the universe
Wang, Tsan-Ming (2024-07-17)With the advent of the Atacama Large Millimeter/submillimeter Array (ALMA), we now have the opportunity to measure the physical properties of the cold, dense, star-forming interstellar medium (ISM) even in distant, ... -
The elucidation of the modes of action of moenomycin and corallorazine A
Fritz, Lisa (2024-07-16)(noch nicht zugänglich / not yet accessible) -
Synthesis and Characterization of Histone Deacetylase (HDAC) Inhibitors and PROTACs
Kraft, Fabian (2024-07-11)Histone deacetylases (HDACs) are a class of enzymes that remove acyl groups from ε-N-lysine residues of histone and non histone proteins. There are 18 human HDAC isoforms, of which 11 have a Zn2<sup>+</sup> ion in their ... -
PDE-based Lossless Medical Image Compression
Jumakulyyev, Ikram (2024-07-09)In this dissertation, our scientific goal is to investigate the potential of Partial Differential Equations (PDEs) for designing a lossless medical image compression codec. <br /> The dissertation consists mainly of ... -
Effects of habitat fragmentation on herpetofauna in Southeast Asia: From broad scale responses to fine scale responses in an ever-changing anthropogenic landscape
Tan, Wei Cheng (2024-07-05)Habitat loss and fragmentation are undoubtedly significant drivers of biodiversity loss worldwide, with Southeast Asia being a hotspot of biodiversity and facing numerous anthropogenic pressures. However, the impacts of ... -
Katalysatoren für die thermische Sauerstoffentwicklungsreaktion
Grimm, Benjamin (2024-07-05)Ziel dieser Arbeit ist es ein geeignetes Anodenmaterial für die PCEC (Protonenkeramikelektrolyse) anhand theoretischer Rechnungen vorauszusagen, welches ausschließlich umweltfreundliche, häufige und kostengünstig verfügbare ... -
Microscopic Theory of Photon Bose-Einstein Condensation
Kajan, Michael Rolf Otto (2024-07-05)We introduce a novel approach for analysing light-matter interactions within driven-dissipative environments. Our study centers on the interaction between dye molecule solutions and photonic cavity modes, mediated by ... -
From the stellar IMF to large-scale structure formation: How the ΛCDM model is incompatible with observations over all probed astrophysical scales
Haslbauer, Moritz (2024-07-05)(noch nicht zugänglich / not yet accessible) -
Identifizierung und Vermeidung von Medikationsfehlern in der Tumortherapie
Weber, Lisa (2024-07-05)Medikationsfehler in der Tumortherapie können fatale Auswirkungen haben. Die kontinuierliche Verbesserung des Medikationsprozesses sowie die Erhöhung der Arzneimitteltherapiesicherheit sind daher von entscheidender Bedeutung. ... -
Establishing SNPSTR Markers to Fight Illegal Wildlife Trade
Mozer, Annika (2024-07-04)(noch nicht zugänglich / not yet accessible) -
Dissecting the cellular effects of antimicrobial agents: The spatio-temporal impact of peptidoglycan synthesis inhibiting antibiotics in Staphylococcus aureus and mechanism of action elucidation of epilancin A37
Puls, Jan-Samuel (2024-07-03)(noch nicht zugänglich / not yet accessible) -
Developing computational protocols for molecular spectroscopy that are able to unravel the photophysical properties of photoluminescent inorganic solid state and organometallic materials
Shafei, Rami Ali Mohamed (2024-07-02)The aim of the thesis is to conduct a thorough examination of photoluminescent inorganic solid-state and organometallic materials through comprehensive theoretical and computational analyses. This involves unraveling the ... -
The redshift evolution of galactic-scale magnetic fields
Kovács, Tímea (2024-06-27)Magnetic fields play an important role in galaxy evolution, however, the redshift evolution of galactic-scale magnetic fields is not well constrained, with only a handful of direct magnetic field strength measurements in ... -
Formulation Development and Optimization via In Vivo Predictive In Vitro and In Silico Tools
Becker, Tim (2024-06-25)(noch nicht zugänglich / not yet accessible)