E-Dissertationen: Search
Now showing items 91-100 of 148
Ondansetron zur Prävention der Hypotonie bei Spinalanästhesie im Rahmen einer Sectio caesarea
(2023-02-15)
Hintergrund: Die primäre - elektive - Sectio caesarea erfolgt üblicherweise in Spinalanästhesie. Eine wesentliche Nebenwirkung der Spinalanästhesie ist eine postinterventionelle Hypotonie, die nicht nur ...
Contribution of SIGLEC-11 and SIGLEC-16 receptors to neuro-inflammation and neurodegeneration
(2023-02-14)
Brain aging is a multifactorial process including accumulation of aged lipids and proteins,
neuroinflammation and loss of neurons. SIGLEC-11 and SIGLEC-16 are paired opposite inhibitory- versus activatory-signaling ...
The impact of pathology, type of resection, and age at surgery on the postoperative seizure and cognitive outcome in patients with temporal lobe epilepsy
(2023-05-12)
In this thesis, epilepsy- and surgery-related factors were investigated for their effects on postoperative seizure and cognitive outcome in patients with medically intractable temporal lobe epilepsy (TLE).
As a first ...
As a first ...
Frühzeitiger Blasensprung vor 24 Schwangerschaftswochen: neonatale Morbidität und Mortalität
(2023-09-18)
Ein Blasensprung vor 24 Schwangerschaftswochen tritt in <1 % aller Schwangerschaften auf. Diese Schwangerschaften wurden vor 1990 meist beendet. Mittlerweile hat sich die Überlebensrate dieser Kinder deutlich verbessert. ...
Hormonal Interactions and Sex Matter: Neural and Behavioral Effects of Estradiol and Oxytocin
(2023-09-25)
The sex hormone estradiol and the neuropeptide oxytocin induce a variety of behavioral and neural effects, but possible underlying interactions have not been tested in a sample involving both sexes. Thus, the current thesis ...
The role of duodenal innate lymphoid cells in familial adenomatous polyposis
(2023-09-18)
Familial adenomatous polyposis (FAP) is an inherited gastrointestinal tumor syndrome. Apart from colonic polyposis and colorectal cancer, the occurrence of duodenal adenomas is the most common intestinal manifestation of ...
The role of cannabinoid receptor 2 in toll-like receptor-mediated microglial activation
(2023-08-29)
Cannabinoid receptor 2 (CB2) modulates microglial responses to inflammatory stimuli. Expression of CB2 is known to increase during chronic inflammation and thus exacerbate neurodegeneration. Results from previous studies ...
Genomweite Analyse von Kopienanzahlveränderungen in 155 Patienten mit angeborener Verengung der Harnröhre zur Identifizierung möglicher kausaler Gene
(2023-08-31)
Die Ursachen für angeborene Obstruktionen des unteren Harntraktes (engl. Lower Urinary Tract Obstruction, LUTO) sind weitgehend unerforscht. Die häufigste Form der LUTO sind angeborene posteriore Urethralklappen (engl. ...
The interplay of fatty acid synthesis, metabolism, and immune function during Flavivirus infection
(2023-10-04)
Macrophage activation and Flavivirus infection can both fundamentally alter cellular metabolism and change the lipid landscape of cells. Flaviviruses upregulate fatty acid synthesis to build membranous replication complexes, ...
From pattern recognition to pro-inflammatory cell death - Functional characterization of the proteins NLRP7 and GSDMD
(2023-12-07)
Inflammasomes are cytosolic multi-protein complexes that form in response to infection or other harmful stimuli to induce innate immune responses. The core components of inflammasomes are pattern recognition ...