Faculties of University Bonn: Fakultäten der Universität Bonn: Recent submissions
Now showing items 701-720 of 10125
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Barriers and Facilitators of Patient Engagement Activities to Improve Patient Safety in Healthcare Organizations: A Delphi-Based Expert Survey
(2024-12-19)<strong>Purpose:</strong> In order to obtain sustainable healthcare, engagement of patients in patient safety improvement is vital. Drawing upon a multi-perspective approach, this study aimed to investigate perspectives ... -
Proteomic screen of dorsal root ganglion neuron growth states reveals Glypican 1 as an autocrine and paracrine activator of axon growth
(2025-08-07)Following an injury in the adult central nervous system (CNS), axons fail to regenerate because of repressed intrinsic growth competence and a cellular environment that lacks growth support. Interestingly, injured axons ... -
Mind wandering, poor sleep, and negative affect: a threefold vicious cycle?
(2024-09-05)Mind wandering (MW) is intricately linked to sleep and affect, bearing clinical relevance for various psychiatric conditions, notably attention deficit/hyperactivity disorder, depression, and anxiety disorders. Most reviews ... -
Brain and Ventricle Volume Alterations in Idiopathic Normal Pressure Hydrocephalus Determined by Artificial Intelligence-Based MRI Volumetry
(2024-07-03)The aim of this study was to employ artificial intelligence (AI)-based magnetic resonance imaging (MRI) brain volumetry to potentially distinguish between idiopathic normal pressure hydrocephalus (iNPH), Alzheimer's disease ... -
Comorbidity profiles among sputum-positive tuberculosis patients in Cameroon
(2024-10-02)<strong>Introduction:</strong> Comorbid non-communicable diseases (NCDs) like diabetes, cardiovascular diseases (CVD), kidney diseases, and hypertension, could have implications for tuberculosis (TB) treatment management ... -
Innovative Regional Services and Heterogeneous Communication Channels: Results from the Nationwide German egePan Project for Pandemic Management
(2024-11-04)<strong>Background:</strong> In the COVID-19 pandemic, novel regional services and communication channels emerged across all sectors of the German healthcare system. To contribute to pandemic preparedness, this study aims ... -
Identifying indicators of apple bud dormancy status by exposure to artificial forcing conditions
(2024-08-31)Dormancy in temperate fruit trees is a mechanism of temporary growth suspension, which is vital for tree survival during winter. Studies on this phenomenon frequently employ scientific methods that aim to detect the timing ... -
Contemporary File System Forensic Analysis
(2025-08-06)This work bridges the gap between traditional and contemporary file system forensic analysis by addressing the limitations of Brian Carrier's foundational 2005 workflow for file system analysis. While Carrier's model has ... -
Imaging of osmiophilic excipients using electron microscopy approaches
(2025-08-06)Drug delivery systems usually contain excipients composed of light elements such as carbon and nitrogen, oxygen. These elements in particular make up the majority of active ingredients and excipients resulting in no or ... -
The impact of stellar feedback on the circumstellar medium and galaxy evolution
(2025-08-06)The formation and evolution of galaxies is an interesting field of study that has attracted considerable interest. One process that affects galaxies is the feedback from stars. It has effects not only in the stellar vicinity, ... -
Chemical Language Models for Molecular Design
(2025-08-06)In drug discovery, chemical language models (CLMs) inspired by natural language processing (NLP) provide innovative solutions for molecular design. CLMs learn the vocabulary, syntax, and conditional probabilities of molecular ... -
Machiavellistische Rollenerwartungen am Arbeitsplatz: Entwicklung und Validierung einer neuen Skala zur Erfassung der aus Mitarbeitendenperspektive wahrgenommenen machiavellistischen Erwartungen von Vorgesetzten
(2025-08-05)Die Arbeitsrolle von Mitarbeitenden ist maßgeblich durch die Erwartungen ihrer Vorgesetzten definiert. Nach der Rollentheorie (Katz & Kahn, 1978) spiegeln sich individuelle Persönlichkeitseigenschaften der Vorgesetzten in ... -
Expressionsmodulation der Hitzeschockproteine HSP27 und HSP70 in malignen Zellen nach Exposition gegenüber nicht-invasivem physikalischem Plasma
(2025-08-05)Aufgrund seines vor allem wachstumshemmenden Effekts auf maligne Zellen gilt Nicht-invasives physikalisches Plasma (NIPP) als vielversprechende Therapieoption in der Onkologie. <br/> Aktuelle Studien konnten eine Beteiligung ... -
Reproduzierbarkeit der quantitativen Auswertung der PSMA-PET
(2025-08-05)<strong>Hintergrund:</strong> Bei Patienten mit Prostatakarzinom, die eine PSMA-gerichtete Radioligandentherapie (RLT) erhalten, korrelieren höhere SUV-Werte mit besseren Therapieergebnissen. Daher ist es entscheidend, die ... -
Investigation and discovery of targetable markers in urological tumors
(2025-08-05)Urological cancers are among the cancers with the highest incidence. In recent years, several therapeutic solutions have been suggested and accepted in the clinic for treatment, but tumors, especially the most aggressive ... -
AIM2-Inhibitory Nanobodies Reveal Differential Activation of AIM2 and NLRP3 Inflammasomes by Poxvirus DNA Genomes in Primary Human Cells
(2025-08-05)Poxviruses are large double-stranded (ds)DNA viruses that replicate in the cytoplasm. While variola virus (VARV) caused millions of deaths before its eradication in 1980, monkeypox virus (MPXV) has been declared a public ... -
New perspectives on semi-parametric and pseudo-value approaches for modeling clinical time-to-event data
(2025-08-04)Clinical decision-making often relies on quantitative measures derived from statistical time-to-event models, enabling risk assessment through the quantification of survival probabilities. A key goal of these modeling ... -
A regulatory duet: sHdrR and SoxR team up for transcriptional repression of sulfur oxidation in Hyphomicrobium denitrificans
(2025-08-04)The Alphaproteobacterium <em>Hyphomicrobium denitrificans</em> X<sup>T</sup>, an obligately chemoorganoheterotrophic methylotroph, uses C<sub>1</sub> compounds like methanol and also C<sub>2</sub> compounds for two purposes: ... -
Anfall und Epilepsie: Morphometrische Kurz- und Langzeitkorrelate im mesialen Temporallappen
(2025-08-04)Epilepsie zählt zu den häufigsten chronischen neurologischen Erkrankungen, wobei die mesiale Temporallappenepilepsie (mTLE) die häufigste Form therapieresistenter Anfälle bei Erwachsenen darstellt. Die häufigste ... -
Biosynthesis of the corallorazines, a widespread class of antibiotic cyclic lipodipeptides
(2024-08-16)Corallorazines are cyclic lipodipeptide natural products produced by the myxobacterium <em>Corallococcus coralloides</em> B035. To decipher the basis of corallorazine biosynthesis, the corallorazine nonribosomal peptide ...
