The Faculty of Medicine: Search
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Extracellular vesicles derived from Hepatitis-D Virus infected cells induce a proinflammatory cytokine response in human peripheral blood mononuclear cells and macrophages
(2020-02-14)
Hepatitis D Virus (HDV) is a satellite virus requiring a Hepatitis B Virus (HBV) envelope
proteins for productive infection. Hepatitis D is the most severe form of viral hepatitis
and is a global health threat affecting ...
Health and Asylum Seekers in Europe
(2015-10)
Job Satisfaction and Chronic Stress of General Practitioners and Their Teams: Baseline Data of a Cluster-Randomised Trial (IMPROVEjob)
(2021-09-08)
Background: A high prevalence of poor job satisfaction and high chronic stress is documented for general practitioners (GPs) and non-physician practice staff from various countries. The reasons are multifactorial and include ......
Intervertebral Disc and Adipokine Leptin—Loves Me, Loves Me Not
(2020-12-31)
Leptin—the most famous adipose tissue-secreted hormone—in the human body is mostly observed in a negative connotation, as the hormone level increases with the accumulation of body fat. Nowadays, fatness is becoming another ...
Experimental Induction of Micro- and Macrosomatognosia: A Virtual Hand Illusion Study
(2021-04-29)
Although body size misperceptions are known to occur under various neurological and psychiatric conditions, their neurocognitive underpinnings are not yet resolved. Accordingly, it would be beneficial to have an experimental ......
Assessing the quality of life of patients with metastatic castration-resistant prostate cancer with bone metastases receiving [223Ra]RaCl2 therapy
(2020-08-19)
[223Ra]RaCl2 dichloride treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) is associated with improved overall survival (OS) and a delay in the time to the first ...
Shedding light on the role of cAMP in mammalian sperm physiology
(2018-06-15)
Mammalian fertilization relies on sperm finding the egg and penetrating the egg vestments. All steps in a sperm's lifetime crucially rely on changes in the second messenger cAMP (cyclic adenosine monophosphate). In recent ...
Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors
(2019-11-14)
The second messenger 3´, 5´-cyclic nucleoside adenosine monophosphate (cAMP) plays a key role in signal transduction across prokaryotes and eukaryotes. Cyclic AMP signaling is compartmentalized into microdomains to fulfil ...
How to control cyclic nucleotide signaling by light
(2017-03-10)
Optogenetics allows to non-invasively manipulate cellular functions with spatio-temporal precision by combining genetic engineering with the control of protein function by light. Since the discovery of channelrhodopsin has ......
Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development
(2022-12-21)
How the vascular and neural compartment cooperate to achieve such a complex and highly specialized structure as the central nervous system is still unclear. Here, we reveal a crosstalk between motor neurons (MNs) and ...