The Faculty of Mathematics and Natural Sciences: Search
Now showing items 11-20 of 60
Mitochondrial regulation through thiol-switching in plants
(2017-10-11)
The seed represents a key stage in the lifecycle of spermatophytes (seed plants). Dry seeds can overcome unfavourable conditions, such as drought, heat or cold, by maintaining their metabolism in a quiescent state. Yet, ...
Molekulare Charakterisierung des trockenstressinduzierten Gens CpGRP1 isoliert aus der Wiederauferstehungspflanze Craterostigma plantagineum
(2017-10-24)
Im Mittelpunkt dieser Arbeit steht die Untersuchung des glycinreichen Proteins CpGRP1 aus der Wiederauferstehungspflanze C. plantagineum, beziehungsweise der für dieses Protein kodierenden Gensequenz und deren Promotor. ......
The Mutant HTT mRNA-Protein Interactome: Implications in RNA Toxicity in Huntington’s Disease
(2017-11-07)
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized by progressive motor, cognitive, and psychiatric symptoms. The mutant gene product contains an elongated stretch of CAG ...
MicroRNA vermittelte Regulation der Expression von Mtss1 während der Entwicklung des Kleinhirns der Maus
(2017-11-14)
Die Entwicklung und Differenzierung des Cerebellums ist von einer regelgerechten Neuritogenese verschiedener Zelltypen abhängig. Dies erfordert eine ständige Umgestaltung des Zytoskeletts und eine Regulation der Zellform. ...
Rapid astrocyte morphology changes during epileptogenesis in the rodent hippocampus
(2017-05-15)
In the past decades astrocytes have been demonstrated to play an important role in physiological brain processes but also neurodegenrative diseases. Their characteristic morphology allows them to closely contact neurons. ...
Unravelling mechanisms causing astrocytic uncoupling in epilepsy
(2017-10-06)
The dynamic regulation of connexins throughout its life cycle has profound impact on the level of gap junctional coupling in astrocytes. Astrocytic uncoupling in epilepsy can be viewed in the context of modifications in ...
Organization and function of signaling molecules in sperm
(2017-09-15)
Successful fertilization depends on the ability of sperm to locate the egg. Sperm from different species rely on diverse signaling components to gather chemical and physical cues and transduce them into a behavioral swimming ......
Um die Eizelle zu befruchten, müssen die Spermien die Eizelle zunächst lokalisieren. Dabei helfen ihnen unterschiedliche chemische oder physikalische Signale auf dem Weg zur Eizelle, die dann das Schwimmverhalten der ......
Um die Eizelle zu befruchten, müssen die Spermien die Eizelle zunächst lokalisieren. Dabei helfen ihnen unterschiedliche chemische oder physikalische Signale auf dem Weg zur Eizelle, die dann das Schwimmverhalten der ......
Peroxin3, a newly identified regulator of melanocyte development and melanosome biogenesis in zebrafish Danio rerio
(2017-04-20)
Previous efforts aimed to understand the consequences of a dysregulated control of peroxisome biogenesis and of the dynamics of peroxisomal matrix proteins. Nevertheless, previous publications did not fill the existing gap ...
Molecular mechanisms of extracellular matrix dynamics at barrier tissues and control of molting in Drosophila
(2017-04-19)
The insect epidermal cuticle acts as the exoskeleton and has crucial barrier functions, protecting against wounding, desiccation, invading pathogens and other environmental dangers. During the life of insects, the epidermal ......
The TsdA family of thiosulfate dehydrogenases/tetrathionate reductases
(2017-04-24)
TsdA enzymes are a phylogenetically widespread family of periplasmic c-type diheme cytochromes which catalyse both thiosulfate oxidation and tetrathionate reduction. The reaction directionality varies between enzymes ...