The Faculty of Mathematics and Natural Sciences: Mathematisch-Naturwissenschaftliche Fakultät: Recent submissions
Now showing items 701-720 of 5008
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Developmental programming of adipose tissue by maternal obesity
(2024-03-25)Tissue-resident macrophages are an integral part of the innate immune system, but their biology is not well understood in the context of metabolic diseases. Distinctive Resident macrophage populations are identified in ... -
Towards enabling precision medicine in Alzheimer's disease and Parkinson's disease
(2024-03-21)Alzheimer's disease and Parkinson's disease are prominent progressive neurodegenerative diseases, with a significant clinical and economic impact on patients, their families, and society as a whole. Despite numerous clinical ... -
Novel Methods for Chiral Molecules in the Gas Phase and Neoteric Solvents
(2024-03-19)This thesis focuses on the development and application of computational methods for the calculation of infrared (IR) and vibrational circular dichroism (VCD) spectra in the gas and liquid phase, with special emphasis on ... -
Stereoselektive Radikalreduktionen durch katalysatorkontrollierten Wasserstoffatomtransfer
(2024-03-15)Diese Dissertation befasst sich mit aktuellen Fortschritten bezüglich stereoselektiver Radikalreduktionen durch katalysatorkontrollierten Wasserstoffatomtransfer über die Titanocen-katalysierte Hydrosilylierung von Epoxiden. ... -
Immune modifying effect of drug free PLGA nanoparticles on the course of experimental autoimmune neuritis (EAN)
(2024-03-15)Experimental autoimmune neuritis (EAN) animal model mimics the human Guillain-Barre syndrome (GBS), an autoimmune disease of demyelination and inflammation of peripheral nerves. Despite advancement in clinical management ... -
Deep Dynamic Language Models
(2024-03-15)This thesis investigates the domain of deep dynamic language models, focusing on the integration of temporal dynamics to enhance language modeling and its application in various tasks, such as text generation, recommendation ... -
Formation and desorption of organic molecules: Resolving their emission in a prominent protostellar hot core and its outflow
(2024-03-15)Star-forming regions are known to be sites of a rich chemistry involving a variety of molecules. Interstellar complex organic molecules (COMs) are thereby of particular interest. They might act as precursors to larger and ... -
Structural and Functional Characterization of Human Transcription-regulating Kinases
(2024-03-12)Accurate regulation of RNA polymerase II by transcriptional kinases is essential for normal development and dysregulation can promote cancer onset and progression. Small molecules targeting transcriptional kinases, such ... -
Charakterisierung des mitochondrialen Stresssensors Pink1 während der Mitophagie
(2024-03-08)Die vorliegende Arbeit beschäftigt sich mit der zentralen Frage der Regulation von Pink1, einer Parkinson-assoziierten Kinase, die in gesunden Zellen als mitochondrialer Stresssensor agiert. Als Folge auf eine starke ... -
Paleobiology and taphonomy of fishes from the Late Cretaceous marine ecosystems of northeastern Mexico
(2024-03-07)The platy limestone deposit of Vallecillo in the northeastern Mexican state of Nuevo León is well known for its exceptionally well preserved faunal assemblage of vertebrate in addition to invertebrate fossils of Late ... -
Synthese und Charakterisierung neuer Thiophosphate mit Chrom und Vanadium
(2024-03-07)Es konnten zehn neue Thiophosphatverbindungen synthetisiert und ihre Kristallstrukturen aufgeklärt werden. Zusätzlich konnten zwei Verbindungen mit bisher ungeklärter Kristallstruktur synthetisiert werden. <br /> ... -
Neural Network-based Signal Isolation and Cross Section Estimation of the tH Process with the ATLAS Detector
(2024-02-29)A measurement of the single top quark production in association with a Higgs boson (tH) gives insight into the properties of not only the top quark but also the Higgs boson. The associated production is sensitive to the ... -
Unitary fermionic topological field theory
(2024-02-29)Atiyah's axioms are one way to define rigorously what is a topological quantum field theory. He defined it as a symmetric monoidal functor from a bordism category to the category of vector spaces. To include fermions in ... -
Low-dimensional Representations for Diverse Collections of 3D Surface Meshes
(2024-02-29)The surfaces of 3D shapes are discretized by surface meshes that represent them in a processable way. This enables simulations of deforming components in CAE, animations for movies, or representations of human organs to ... -
Zintl Anions, Polychalcogenides and Chalcogenometalates via Solvothermal Syntheses
(2024-02-29)The focus of this work is on the synthesis and structural investigation of polychalcogenides and <em>Zintl</em> phases. Therefore, mainly ammonothermal syntheses under mild or supercritical conditions were used. Additionally, ... -
Large scale in vivo recordings of dentate gyrus granule cells during trace eyeblink conditioning
(2024-02-29)The dentate gyrus (DG) is known to play a role in associative learning, but the precise contribution of individual granule cells (GC) to this process remains unclear. In this study, we established a head-fixed trace eyeblink ... -
Home range and ecology of a palaearctic lacertid: Combining novel and old approaches to assess Lacerta agilis LINNAEUS, 1758 in the centre of its distribution with considerations for conservation
(2024-02-28)Effective species conservation requires a thorough understanding of a species’ ecology as it reveals the requirements a species has of its environment. In this thesis I combine established methods like visual encounter ... -
Erstellung reiner Pollenkonzentrate mittels Durchflusszytometrie für die 14C-Datierung zur Bildung einer Chronologie für die holozänen Sedimente des Vansees
(2024-02-27)Die <sup>14</sup>C-Datierung von makroskopischen Pflanzenresten ist eine weit verbreitete Methode, das Alter von Seesedimenten präzise zu bestimmen. Das Fehlen großer Makrofossilien in vielen limnischen Klimaarchiven, die ... -
On the enigmatic mechanism of signal transduction of "arrestin-biased" angiotensin peptides: spotlight on endogenous angiotensin 1-7
(2024-02-27)The renin-angiotensin system (RAS) plays a central role in the maintenance of water and electrolyte balance in the body and is therefore one of the most important regulatory cascades for the control of physiological blood ... -
Erweiterung der genetischen Werkzeuge für das Darmbakterium Phocaeicola vulgatus zur Untersuchung des Katabolismus und des Phenolsäure-Stoffwechsels
(2024-02-26)Die vorliegende Arbeit befasst sich mit der Erweiterung der genetischen Zugänglichkeit des relevanten Darmbakteriums <em>Phocaeicola</em> (P.) <em>vulgatus</em> mit dem Ziel, eine reproduzierbare und zuverlässige Methode ...
