Mathematisch-Naturwissenschaftliche Fakultät: Mathematisch-Naturwissenschaftliche Fakultät: Neuzugänge
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Das Cyclodepsipeptid FR900359: Ein Insektizid mit neuem Wirkmechanismus aus Cand. Burkholderia crenata und Chromobacterium vaccinii
(2024-01-16)Sekundärmetabolite (SM) sind für ihr breites Spektrum an Bioaktivitäten bekannt und daher eine wichtige Quelle für neue Arzneimittelkandidaten. Neben ihrer Relevanz für die Therapie von Erkrankungen sind SM und ihre ... -
The role of glutaredoxin S15 in the transfer of Fe–S clusters and their consumption by lipoyl synthase in Arabidopsis mitochondria
(2024-01-15)Iron–sulfur (Fe–S) clusters are vital cofactors in all domains of life. The mitochondrial Fe–S cluster biogenesis occurs through two major steps: the initial construction of [2Fe–2S] clusters, followed by their assembly ... -
Optogenetic investigation of local adrenaline signaling effects on cardiac arrhythmia mechanisms
(2024-01-15)Ventricular arrhythmias are one of the major causes of death worldwide, occurring especially in structurally remodeled hearts, but also in hereditary conditions, such as CPVT, in which mutations in RyR2 or Casq2 cause ... -
Functional morphology of an adaptive radiation – sailfin silversides from Sulawesi as a model system
(2024-01-11)The adaptive fish radiation of sailfin silversides from Sulawesi serves as a model system for studying adaptive divergence. The phylogenetic lineage of “roundfins” is endemic to ancient Lake Matano and is composed of three ... -
Determination of |Vcb| and form factors of B̄0 → D*+ℓ−ν̄ℓ decays with Belle II data
(2024-01-11)<p>This thesis presents a determination of the Cabibbo-Kobayashi-Maskawa (CKM) matrix element magnitude |<em>V<sub>cb</sub></em>| and form-factor parameters of <em>B̄<sup>0</sup> → D<sup>*+</sup>ℓ<sup>−</sup>ν̄</em><sub>ℓ</sub> ... -
Characterizing Time-Evolving Functional Networks
(2024-01-10)Understanding spatially-extended, complex dynamical systems is a vital task in the natural sciences. From the climate over eco-socio-cultural systems to the human brain, time-evolving complex systems abound. These systems ... -
Entwicklung eines Airystrahl-Lichtscheibenmikroskops in Verbindung mit einer Deep Learning-basierten Bildoptimierung
(2024-01-08)Für die Erforschung und das Verständnis komplexer Strukturen im Gehirn ist die Erfassung sowohl kleinster Details als auch ganzer Hirnareale notwendig. Die Umsetzung dieser Kombination von hoher Auflösung und großem Sichtfeld ... -
Pentaquark Search in Λ0b → Λ+c D D*0K- Decays and LHCb Open Data Release
(2024-01-08)This PhD thesis reports results of the physics analysis focused on the search of pentaquarks in Lb->LcDstK decays. Pentaquarks were first reported in 2015 by the LHCb collaboration in jpsi proton system. After collecting ... -
Lessons Learned from PARADeS Project for Flood Disaster Risk Planning and Management in Ghana
(2024-01)The PARADeS project focused on Ghana’s national flood disaster risk reduction and management strategy by investigating existing flood risk and mechanisms for disaster management, governance-policy, human-water interaction, ... -
Self-organized branching morphogenesis: Study of a related FKPP-system, and a case study of prostate cancer
(2024-01-03)The group of E. Hannezo et al. proposed "A Unifying Theory of Branching Morphogenesis" in glandular epithelial tissues in 2017, based on a stochastic model related to branching and annihilating random walks. In this ... -
Spectroscopy of Xenon and Xenon-Noble Gas Mixtures for Bose-Einstein Condensation of Vacuum-Ultraviolet Photons
(2024-01-03)Bose-Einstein condensation of photons has first been observed in 2010 by the group of Martin Weitz in Bonn. In the experimental scheme, a photon gas is confined to a wavelength-size microcavity filled with a liquid dye ... -
Characterization of the immune system-drug interactions during anti-filarial treatment in the Litomosoides sigmodontis mouse model
(2024-01-03)Filarial nematodes can cause debilitating diseases such as lymphatic filariasis and onchocerciasis. Both diseases are included in the list of neglected tropical diseases as defined by the World Health Organization (WHO) ... -
Sleep and navigation in Drosophila
(2023-12-20)Sleep plays an essential role in life and is critical for the optimal functioning of the brain, for example in learning and memory. Drosophila displays many of the signatures of sleep observed in mammals or humans, including ... -
Neural mechanisms involved in visual learning in the cichlid fish Pseudotropheus zebra
(2023-12-20)Although several studies have investigated the cognitive abilities in fish, not so much is known about where the cognitive information is processed in the brain. For this PhD thesis I assessed visual learning and its neural ... -
Global-Local Techniques for Fracture
(2023-12-20)In the numerical simulation of components and structures it is necessary to incorporate the effect of localized damage and its propagation. However, simulating fracture on top of linear elasticity in three space dimensions ... -
Algebraic Multigrid for Eigenproblems in Industrial Applications of Big Data and Engineering
(2023-12-18)More and more data are generated and gathered by computational simulations, network evaluations, and sensor usage in industrial applications and many other methods. To make the most out of the collected data, these should ... -
Search for Higgs Boson Pair Production in the bb̅τ+τ- Final State with the ATLAS Experiment at the LHC
(2023-12-18)A search for Higgs boson pair (<i>HH</i>) production in final states with two <i>b</i> quarks and two <i>τ</i> leptons using 139 fb<sup>-1</sup> of proton–proton collision data at a centre-of-mass energy of 13 TeV recorded ... -
Synthese von Molekülen und metallosupramolekularen Aggregaten zur Parkettierung von HOPG-Oberflächen und deren theoretische Beschreibung
(2023-12-18)Die vorliegende Arbeit befasst sich mit der Adsorption und Selbstorganisation von organischen Molekülen an der fest/flüssig-Grenzfläche zu hochorientiertem pyrolytischen Graphit (HOPG). Unter den richtigen Bedingungen ... -
Innovative Pharmaceutical Stabilization and Formulation Techniques for Protein Drugs
(2023-12-18)Solid protein formulations for peroral, nasal or parenteral administration would significantly improve the therapeutic use, compliance, and stability of protein-based drugs. The aim of this work was to develop, apply, and ... -
Katalytische Aktivität ternärer Übergangsmetalloxide
(2023-12-18)In dieser Arbeit wurden mittels quantenchemischer Methoden ternäre Übergangsmetalloxide, M<sub>x</sub>Ti<sub>1–x</sub>O<sub>2</sub> und ZnFe<sub>2</sub>O<sub>4</sub>, auf ihre Eignung als Katalysatoren für die Wasserspaltung ...
