bonndoc - Der Publikationsserver der Universität Bonn: Recent submissions
Now showing items 321-340 of 11868
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Across Diagnostic Boundaries: Genetic Variants for Neuropsychiatric Disorders and their Association with Human Brain Structure
(2025-08-11)With the advances in genome-wide association studies (GWAS), hundreds of genetic variants have been identified for neuropsychiatric disorders. Strikingly, many of these genetic variants showed complex associations across ... -
NIS-Seq enables cell-type-agnostic optical perturbation screening
(2024-12-19)Optical pooled screening offers a broader-scale alternative to enrichment-based perturbation screening, using fluorescence microscopy to correlate phenotypes and perturbations across single cells. Previous methods work ... -
Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei
(2024-12-10)<strong>Background:</strong> <em>Mansonella perstans</em> is transmitted by <em>Culicoides</em> species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis ... -
Digital platforms in the agricultural sector: Dynamics of oligopolistic platformisation
(2024-12-26)This paper introduces the concept of 'oligopolistic platformisation' to capture the specific dynamics of collaboration and competition between multinational upstream agribusinesses and Big Tech companies in the agricultural ... -
Comparative Analysis of Shear Bond Strength in Orthodontic Brackets Between Milled and 3D-Printed Definitive CAD/CAM Restorations
(2024-10-18)<strong>Objective:</strong> The objective of this study was to evaluate the effect of different surface treatment methods on the shear bond strength (SBS) of metal brackets bonded to two types of CAD/CAM composite restorations: ... -
Schistosomiasis–Microbiota Interactions: A Systematic Review and Meta-Analysis
(2024-10-16)Introduction: Schistosomiasis, a tropical disease affecting humans and animals, affected 251.4 million people in 2021. <em>Schistosoma mansoni, S. haematobium, S. intercalatum</em>, and <em>S. japonicum</em> are primary ... -
Entwicklung und Validierung eines Screeninginstrumentes zur Diagnose einer Sepsis nach Schlaganfall
(2025-08-08)Schlaganfall-assoziierte Infektionen können eine Sepsis hervorrufen, die mit einem schlechten klinischen Outcome assoziiert ist. Die lebensbedrohliche Organdysfunktion, welche die Sepsis definiert, kann mittels Sequential ... -
The ethnoarchaeology of pottery tempers in the bolivian Amazon: Two indigenous traditions of paste recipes with preparations of freshwater sponge, pottery sherds, bone, and turtle shell
(2024-10-14)This article integrates ethnoarchaeological investigations of the pottery <em>chaîne opératoire</em> from two research projects conducted with Indigenous peoples of the Llanos de Moxos region in the Bolivian Amazon. Two ... -
Single-neuron representations of odours in the human brain
(2024-10-09)Olfaction is a fundamental sensory modality that guides animal and human behaviour. However, the underlying neural processes of human olfaction are still poorly understood at the fundamental—that is, the single-neuron—level. ... -
The multiple dimensions of resilience in agricultural trade networks
(2024-09-24)The global food and agricultural trade network is crucial for food security. Shocks such as those posed by extreme weather events, conflicts, pandemics, and economic crises can test the resilience of the trade network to ... -
Developmental programming of tissue-resident macrophages
(2024-11-07)Macrophages are integral components of the innate immune system that colonize organs early in development and persist into adulthood through self-renewal. Their fate, whether they are replaced by monocytes or retain their ... -
Further Insights into a Late Classic Maya Relief Panel of Unknown Provenance, Repatriated to Mexico in 2025
(2025-07-23)This contribution presents new insights into a Late Classic Maya limestone relief panel of unknown provenance, repatriated to Mexico in 2025. The artifact, intricately carved and culturally significant, likely originated ... -
The importance of edges in complex networks
(2025-08-08)The sun, the climate, world politics, the stock market, or the human brain, complex networked systems are deeply intertwined in the world we live in. Their dynamics, which include unexpected and catastrophic extreme events, ... -
Mikrobielle Kontamination auf temporären Herzschrittmacher-Elektroden nach Transkatheter-Aortenklappen-Implantation und deren Einfluss auf klinischen Verlauf
(2025-08-08)Hintergrund und Zielsetzung: <br/> Die Transkatheter-Aortenklappenimplantation (TAVI) ist eine etablierte Behandlungsoption für Patienten mit symptomatischer, hochgradiger Aortenklappenstenose – unabhängig vom chirurgischen ... -
Microbial Spectrum, Intraoperative Findings, and Postoperative Outcomes in Native Knee Joint Infections: A Retrospective Analysis
(2024-12-16)<strong>Background:</strong> Native knee joint infections, while uncommon, present a serious condition predominantly instigated by bacteria such as <em>Staphylococcus aureus</em>. Without timely intervention, they can ... -
From Language Models to Medical Diagnoses: Assessing the Potential of GPT-4 and GPT-3.5-Turbo in Digital Health
(2024-12-02)Background: Large language models (LLMs) like GPT-3.5-Turbo and GPT-4 show potential to transform medical diagnostics through their linguistic and analytical capabilities. This study evaluates their diagnostic proficiency ... -
Understanding student engagement in vaccination education: An interview-based multi-stakeholder study
(2024-12-06)The COVID-19 pandemic has underscored the importance of informed decision-making, especially concerning vaccination for disease prevention. This highlights the need for scientific literacy, trust, and understanding of ... -
Characterization of the disorganization of the inner retinal layers in diabetics using increased axial resolution optical coherence tomography
(2025-01-13)<strong>Purpose:</strong> To compare a novel high-resolution optical coherence tomography (OCT) with improved axial resolution (High-Res OCT) with conventional spectral-domain OCT (SD-OCT) with regard to their capacity to ... -
Barriers and Facilitators of Patient Engagement Activities to Improve Patient Safety in Healthcare Organizations: A Delphi-Based Expert Survey
(2024-12-19)<strong>Purpose:</strong> In order to obtain sustainable healthcare, engagement of patients in patient safety improvement is vital. Drawing upon a multi-perspective approach, this study aimed to investigate perspectives ...
