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Motivational drivers and the effectiveness of conservation incentives
Nyanghura, Qambemeda M.; Börner, Jan; Biber-Freudenberger, Lisa (2025-12-24)The debate about how external incentives (e.g., payments for ecosystem services) and internal motivations (e.g., intrinsic values) interact in producing conservation outcomes is still unresolved. This paper examines the ... -
Longitudinal Study of SARS-CoV-2 Vaccinations and Infections in Patients with Gastrointestinal Cancer: Stabilizing Immune Responses and Neutralizing Emerging Variants with Variant-Adapted Antigen Exposures
Gonzalez-Carmona, Maria A.; Schmitz, Alina M.; Berger, Moritz; Baier, Leona I.; Gorny, Jens G.; Sadeghlar, Farsaneh; Anhalt, Thomas; Zhou, Xin; Zhou, Taotao; Mahn, Robert; Möhring, Christian; Linnemann, Thomas; Schmid, Matthias; Strassburg, Christian P.; Boesecke, Christoph; Rockstroh, Jürgen K.; Eis-Hübinger, Anna-Maria; Monin, Malte B. (2024-12-19)This longitudinal study examined how active gastrointestinal (GI) cancer types affect immune responses to SARS-CoV-2, focusing on the ability to neutralize the Omicron variants. Patients with GI cancer (<em>n</em> = 168) ... -
Urban households' food safety knowledge and behaviour: Choice of food markets and cooking practices
Dzudzor, Makafui I.; Gerber, Nicolas (2023-08-06)Food safety is a public health issue and a shared responsibility of everyone. Traditional food markets can be high-risk locations for the spread of foodborne diseases, especially in developing countries. The focus has been ... -
Wheat Farmers' Perception of Constraints and Their Adaptive Capacity to Changing Demands in Egypt
Abdalla, Ahmed; Stellmacher, Till; Becker, Mathias (2023-08-03)Most of the approximately 105 million Egyptians depend on wheat in the form of baladi bread for their daily diet. Millions of smallholders along the River Nile have produced wheat for millennia; however, in more recent ... -
Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma
Sadeghlar, Farsaneh; Seelemann, Julia; Vogt, Annabelle; Möhring, Christian; Zhou, Taotao; Mahn, Robert; Kornek, Miroslaw; Lukacs-Kornek, Veronika; Casares, Noelia; Lasarte, Juan José; Sarobe, Pablo; Beekum, Cornelius van; Matthaei, Hanno; Manekeller, Steffen; Kalff, Jörg; Schmidt-Wolf, Ingo G.H.; Strassburg, Christian P.; Gonzalez-Carmona, Maria A. (2023-10-17)<strong>Background & Aims:</strong> Vaccination with tumor-associated antigen-pulsed dendritic cells leads to specific T-cell response against hepato-cellular carcinoma. However, clinical response has been shown to be ... -
Tackling Structural Injustices: On the Entanglement of Visibility and Justice in Emerging Technologies
Braun, Matthias; Bleher, Hannah; Hille, Eva Maria; Krutzinna, Jenny (2023-06-20)In today's world, Artificial Intelligence plays a central role in many decision-making processes. However, its use can lead to structural and epistemic injustices— especially in the context of health. In 2019, for example, ... -
Epidemiology and outcomes of vancomycin-resistant enterococcus infections: A systematic review and meta-analysis
Eichel, Vanessa M.; Last, Katharina; Brühwasser, Christina; Baum, Heike von; Dettenkofer, Markus; Götting, Tim; Grundmann, Hajo; Güldenhöven, Hanna; Liese, Jan; Martin, Maria; Papan, Cihan; Sadaghiani, Catharina; Wendt, Constanze; Werner, Guido; Mutters, Nico (2023-09-19)Vancomycin-resistant enterococci (VRE) cause many infections in the healthcare context. Knowledge regarding the epidemiology and burden of VRE infections, however, remains fragmented. We aimed to summarize recent studies ... -
Evaluating AI Courses: A Valid and Reliable Instrument for Assessing Artificial-Intelligence Learning through Comparative Self-Assessment
Laupichler, Matthias Carl; Aster, Alexandra; Perschewski, Jan-Ole; Schleiss, Johannes (2023-09-26)A growing number of courses seek to increase the basic artificial-intelligence skills ("AI literacy") of their participants. At this time, there is no valid and reliable measurement tool that can be used to assess AI-learning ... -
The European Research Infrastructure Consortium (ERIC) as the New Normal?: Change and Continuity in Organising European Research Infrastructures since the Early 2000s
Rüffin, Nicolas V.; Cramer, Katharina C.; Tiemann, Maren (2024)The establishment of Research Infrastructures in Europe, often referred to as Big Science, has been a consistent focus of ad-hoc intergovernmental politics among member states and international partners since the latter ... -
Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years
Saßmannshausen, Marlene; Döngelci, Senem; Vaisband, Marc; Emde, Leon von der; Sloan, Kenneth R.; Hasenauer, Jan; Holz, Frank G.; Schmitz-Valckenberg, Steffen; Ach, Thomas (2024-04-30)<strong>PURPOSE.</strong> To longitudinally assess the impact of high-risk structural biomarkers for natural disease progression in non-exudative age-related macular degeneration (AMD) on spatially resolved mesopic and ... -
Key factors for sustainable working conditions in emergency departments: An EUSEM-initiated, Europe-wide consensus survey
Weigl, Matthias; Lifschitz, Michael; Dodt, Christoph (2025-02)<em>Background and importance</em> Modern emergency medicine (EM) is a complex, demanding, and occasionally stressful field of work. Working conditions, provider well-being, and associated health and performance outcomes ... -
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function
Khani, Sajjad; Topel, Hande; Kardinal, Ronja; Tavanez, Ana Rita; Josephrajan, Ajeetha; Larsen, Bjørk Ditlev Marcher; Gaudry, Michael James; Leyendecker, Philipp; Meincke Egedal, Nadia; Güller, Aylin Seren; Stanic, Natasa; Ruppert, Phillip M. M.; Gaziano, Isabella; Hansmeier, Nils Rouven; Schmidt, Elena; Klemm, Paul; Vagliano, Lara-Marie; Stahl, Rainer; Duthie, Fraser; Krause, Jens-Henning; Bici, Ana; Engelhard, Christoph Andreas; Gohlke, Sabrina; Frommolt, Peter; Gnad, Thorsten; Rada-Iglesias, Alvaro; Pradas-Juni, Marta; Schulz, Tim Julius; Wunderlich, Frank Thomas; Pfeifer, Alexander; Bartelt, Alexander; Jastroch, Martin; Wachten, Dagmar; Kornfeld, Jan-Wilhelm (2024-04-29)Promoting brown adipose tissue (BAT) activity innovatively targetsobesity and metabolic disease. While thermogenic activation of BAT is wellunderstood, the rheostatic regulation of BAT to avoid excessive energy dissipation ... -
Exploring the role of tryptophan in biennial bearing: A mobile molecule that is exported from growing apples but does not suppress flowering
Milyaev, A.; Klaiber, I.; Tandron-Moya, Y.A.; Lempe, J.; Pfannstiel, J.; Luedeling, E.; Wirén, N. von; Flachowsky, H. (2024-12-23)<em>Background of the study</em> – <strong>Apple (<em>Malus × domestica</em> Borkh.) production faces significant challenges, with biennial (or alternate) bearing being a major obstacle to stable yields. Natural high crop ... -
How legitimate are urban climate planning processes?: A comparative assessment of Accra, Ahmedabad, Bonn and São Paulo
Wagner, Niklas; Pathak, Minal (2025-01-20)Urban climate action plans (UCAPs) guide cities in identifying key climate risks and in addressing climate change. Designed to guide urban transformation over decades through near-term and long-term actions reducing emissions ... -
The Spectrum of Functional, Structural and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report
Terheyden, Jan Henrik; Holz, Frank G.; Behning, Charlotte; Dunbar, Hannah M.P.; Schmitz-Valckenberg, Steffen; Tufail, Adnan; Schmid, Matthias; Crabb, David P.; Saßmannshausen, Marlene; Binns, Alison; Hoyng, Carel B.; Zakaria, Nadia; Poor, Stephen; Moll, Klaus-Peter; Cosette, Deborah; Martinho, Cecília; Batuca, Joana; Cunha-Vaz, José; Luhmann, Ulrich F.O.; Leal, Sergio; Finger, Robert P. (2025-02-03)<em><strong>Introduction:</strong></em> There is an unmet medical need for therapies in intermediate age-related macular degeneration (iAMD). The prospective European multi-center cohort study MACUSTAR validates structural, ... -
Bytes the Dust: Normative Notions in Decommissioning Digital Doppelgängers
Barnhart, Andrew J.; Comerci, Giuseppe; Braun, Matthias (2025-01-29)In recent debates on digital twins, much attention has been paid to understanding the interaction between individuals and their digital representations (Braun, 2021). Iglesias et al. (2025) shed new light on this debate, ... -
The hard work of future-making: Alienated futures, invisible labour and liberation
Aalders, Theo; Müller-Mahn, Detlef (2025-01-02)This article proposes that future-making is hard work. Drawing on examples of work on and around infrastructure projects in East Africa, we show how people orient themselves towards the future through both imagination and ... -
Deep Learning–Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy
Pinedo-Diaz, German; Lorenz, Birgit; Künzel, Sandrine H.; Thiele, Sarah; Ortega-Cisneros, Susana; Bayro Corrochano, Eduardo; Holz, Frank G.; Effland, Alexander (2025-01-02)<strong>PURPOSE.</strong> To quantify outer retina structural changes and define novel biomarkers of inherited retinal degeneration associated with biallelic mutations in <em>RPE65 (RPE65</em>-IRD) in patients before and ... -
TFAP2E is implicated in central nervous system, orofacial and maxillofacial anomalies
Kalanithy, Jeshurun C.; Mingardo, Enrico; Stegmann, Jil D.; Dhakar, Ramgopal; Dakal, Tikam Chand; Rosenfeld, Jill A.; Tan, Wen-Hann; Coury, Stephanie A.; Woerner, Audrey C.; Sebastian, Jessica; Levy, Paul A.; Fleming, Leah R.; Waffenschmidt, Lea; Lindenberg, Tobias T.; Yilmaz, Öznur; Channab, Khadija; Babra, Bimaljeet K.; Christ, Andrea; Eiberger, Britta; Hölzel, Selina; Vidic, Clara; Häberlein, Felix; Ishorst, Nina; Rodriguez-Gatica, Juan E.; Pezeshkpoor, Behnaz; Kupczyk, Patrick A.; Vanakker, Olivier M.; Loddo, Sara; Novelli, Antonio; Dentici, Maria L.; Becker, Albert; Thiele, Holger; Posey, Jennifer E.; Lupski, James R.; Hilger, Alina C.; Reutter, Heiko M.; Merz, Waltraut M.; Dworschak, Gabriel C.; Odermatt, Benjamin (2024-12-23)<strong>Background</strong> Previous studies in mouse, <em>Xenopus</em> and zebrafish embryos show strong <em>tfap2e</em> expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in ... -
Ergebnisse von abdomino-thorakalen Eingriffen am Lymphgefäßsystem zur Behandlung traumatischer und nicht-traumatischer Lymphleckagen
Kaminski, Lea Caterina (2025-08-11)<strong>Hintergrund:</strong><br /> Chylöse Ergüsse wie Chylothorax oder Chylaszites stellen seltene, aber schwerwiegende Krankheitsbilder dar, die häufig mit hoher Morbidität und Mortalität einhergehen. Ziel dieser Studie ...






















