E-Dissertationen: Auflistung E-Dissertationen nach Titel
Anzeige der Dokumente 3048-3067 von 4070
-
Regulation und funktionelle Bedeutung der Arginase und Arginase-abhängiger Stoffwechselwege in Atemwegszellen der Ratte
(2009-01-20)Das Enzym Arginase, besonders die Isoform Arginase I, ist klassischerweise ein Enzym des Harnstoffzyklus, der seine Bedeutung in der Entgiftung von Ammoniak in der Leber findet. In zahlreichen extrahepatischen Zellen und ... -
Regulatorische Funktion der Phosphorylierung von Neprilysin in der Lokalisation an der Plasmamembran und der Interaktion mit dem Tumorsuppressor PTEN
(2010-04-23)Bei der Zink-Metalloendopeptidase Neprilysin (NEP) handelt es sich um ein Typ 2 Membranprotein, das für die Degradation von extrazellulären Peptiden und Peptidhormonen zuständig ist. Darüber hinaus kann NEP sowohl im ... -
Regulatory mechanisms in cross-presentation in vivo
(2007)Dendritic cells can present exogenous antigen to CD8 T cells using a mechanism termed cross-presentation. This mechanism is important for immune responses against tumors, viruses, intracellular pathogens and autoantigens ... -
Rekonstruktion von Metamorphosepfaden mit stabilen Isotopen: Möglichkeiten der Laserfluorinierung am Beispiel des Sächsischen Granulitgebirges
(2002)Diese Arbeit beschäftigt sich mit der Analyse von Sauerstoffisotopen und der Auswertung und Interpretation der bestimmten Gleich- bzw. Ungleichgewichte. Ein wesentlicher Schwerpunkt der Arbeit liegt auf der Bestimmung von ... -
Rekristallisation von teilamorpher und amorpher Laktose: Charakterisierung von physiko-chemischen Eigenschaften und Tablettierbarkeit
(2011-07-04)Für die pharmazeutische Entwicklung und die Produktion von Arzneimitteln sind Kenntnisse über mögliche Umwandlungen von Wirk- und Hilfsstoffen während der Verarbeitung und der Lagerung wichtig und erstrebenswert.
... -
The Relationship between Astrocytes, Inflammation and Epileptogenesis
(2017-08-23)Previous studies provided evidence that FSs in children increase the risk of epilepsy development. EFSs in animals confirmed this assumption. EFS generated with only hyperthermia induction caused astrocyte uncoupling, which ... -
Relative singularity categories
(2013-12-05)In this thesis, we study a new class of triangulated categories associated with singularities of algebraic varieties. For Gorenstein rings, triangulated singularity categories were introduced by Buchweitz. In 2006 Orlov ... -
Relative unitary RZ-spaces and the Arithmetic Fundamental Lemma
(2017-03-29)We verify new cases of the Arithmetic Fundamental Lemma (AFL) of Wei Zhang. This relies on a recursive algorithm which allows, under certain conditions, to reduce the AFL identity in question to an AFL identity in lower ... -
Relevance of cGAMP-mediated bystander cell activation and cooperation of cGAS and TLR signaling in TREX1-related autoimmunity
(2020-11-05)The aberrant recognition of endogenous nucleic acids by innate immune sensors can trigger a wide range of autoimmune and autoinflammatory conditions, mediated by type I interferons. Laoss-of-function mutations in the three ... -
Relevance of glutathione and MRP-mediated efflux for platinum resistance
(2013-09-03)Therapeutic resistance towards platinum complexes is a multicausal interaction of diverse mechanisms. This project aimed to reveal the role of GSH and MRP-mediated efflux. Elevated GSH content, formation of platinum-GSH ... -
The relevance of myeloid-derived suppressor cells during Litomosoides sigmodontis infection
(2018-05-23)68 million people are infected with lymphatic filariasis (LF) in Sub-Saharan Africa, South-East Asia and South America, causing a major health problem with economic repercussions among the infected populations. This disease ... -
Relic Abundance of WIMPs in Non-standard Cosmological Scenarios
(2007)In this thesis we study the relic density $n_{\chi}$ of non--relativistic long--lived or stable particles $\chi$ in various non--standard cosmological scenarios. First, we discuss the relic density in the non--standard ... -
Die reliefabhängige Schneedeckenverteilung im Hochgebirge: ein multiskaliger Methodenverbund am Beispiel des Lötschentals (Schweiz)
(2007)Das kleinräumig und zeitlich variierende Verteilungsmuster der Schneedecke steuert im Hochgebirge maßgeblich das ökosystemare Prozessgeschehen, so dass dessen Erfassung für weitergehende Analysen und ökosystemare ... -
Remote sensing based assessment of land cover and soil moisture in the Kilombero floodplain in Tanzania
(2018-08-15)Wetlands provide important ecological, biological, and social-economic services that are critical for human existence. The increasing demand for food, arable land shortage and changing climate conditions in East Africa ... -
Remote sensing based assessment of small wetlands in East Africa
(2010-11-26)Small wetlands in East Africa have in the past few decades become focal points of a broad spectrum of agricultural production and other land-uses. Climate change and population growth are the major factors attributing to ... -
Renormalisation in discrete elasticity
(2019-10-10)This thesis deals with the statistical mechanics of lattice models. It has two main contributions. On the one hand we implement a general framework for a rigorous renormalisation group approach to gradient models. This ... -
A reporter cell system for TREM2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region
(2021-06-08)The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor expressed on myeloid-derived cell types. The extracellular immunoglobulin-like domain of TREM2 binds anionic ligands including Apolipoprotein ... -
Representation of deep convection at gray-zone resolutions - Implementing and testing the HYbrid MAss flux Convection Scheme (HYMACS) in the ICON model
(2022-07-08)Despite the increasing computing resources, the grids of contemporary atmospheric models are often still too coarse to explicitly represent convective processes. Since these processes are known to be an important driver ... -
Representations of the Kottwitz gerbes
(2022-03-15)Let F be a local or global field and let G be a linear algebraic group over F. We study Tannakian categories of representations of the Kottwitz gerbes Rep(Kt_F) and the functor G → B(F,G) defined by Kottwitz in [28]. In ... -
The reproductive biology of Cretaceous oviraptorid dinosaurs and its implication for the origin of bird reproduction
(2018-11-13)This dissertation aims to pioneer an integrative approach that includes all lines of evidence to comprehensively and in detail reconstruct the biology of an extinct animal. Specifically, the dissertation consists of several ...
