E-Dissertationen: Auflistung E-Dissertationen nach Klassifikation (DDC) "ddc:570"
Anzeige der Dokumente 1-20 von 1148
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Acceleration of microglial clearance function by small TREM2-activating anionic disaccharides
Nunes de Paiva, Vanessa (2014-07-29)Triggering receptor expressed on myeloid cells-2 (TREM2) is an innate immune receptor, which is expressed on myeloid cells, like microglia inside the central nervous system. TREM2 signals via the adaptor protein DAP12. ... -
Acetylcholine mediates protective immune responses against the rodent filarial nematode Litomosoides sigmodontis
Neumann, Anna Lena (2022-02-22)Tropical infectious diseases are caused by parasitic helminths, such as lymphatic filariasis and onchocerciasis (river blindness). Filariae have the ability to modulate the immune response of their host in order to be ... -
Actin cytoskeleton and endomembrane system dependent cell growth
Voigt, Boris (2008)In plants, membrane recycling processes are involved in every instance of cell volume changes which occur during growth, development and adaptation to the environment. The thesis work described here addresses membrane ... -
Actin Regulatory Proteins in Dendritic Arborisation Neurons of Drosophila
Stürner, Tomke (2019-10-23)Dendrites are highly branched extensions of nerve cells, along which signals are received and propagated to the cell body. The correct morphology of dendrites is essential for the function of the nervous system. The ... -
Action of zona pellucida glycoproteins in mouse and human sperm
Balbach, Melanie (2017-08-22)For fertilization, sperm have to penetrate the oocyte’s vestment, the zona pellucida (ZP). In mouse and human, the ZP consists of three or four different ZP glycoproteins, respectively. Binding of sperm to ZP glycoproteins ... -
Activation Mechanisms of RIG-I
de Regt, Ann Kristin (2020-11-02)(noch nicht zugänglich / not yet accessible) -
Activity-Dependent Regulation of Neuronal Ion Channel Expression During Epileptogenesis
Chen, Jian (2005)Status epilepticus (SE) is known to cause numerous structural and functional alterations in brain. In this study, expression of various voltage-gated ion channels in rat hippocampal CA1 neurons were investigated at different ... -
The Acyl-ACP Thioesterase FatM from Lotus japonicus is involved in lipid transfer during Arbuscular Mycorrhiza Symbiosis
Brands, Mathias (2020-01-27)Arbuscular mycorrhiza colonization of roots is an ancient symbiosis that presumably was involved in the conquest of the land by early plants. Its main benefit for plants is the increased access to soil mineral nutrients ... -
Advanced migration assays for studying chemotaxis of slow moving cells
Tomášová, Lea (2021-12-16)Chemotaxis of slow moving cells plays a crucial role in numerous physiological and pathophysiological processes; including tumour metastasis, development, and wound healing. Therefore, a comprehensive understanding of ... -
Advanced population pharmacokinetic modelling to quantify selected characteristics of drugs
Abduljalil, Khaled Mohammed Abdulwahab (2010-08-03)The ophthalmic lyophilisate formulation has been known for its safety, tolerability, and ability to achieve higher concentrations of a drug in the internal tissue of the eye compared with the conventional eye drop. Based ... -
AHRD: Automatically Annotate Proteins with Human Readable Descriptions and Gene Ontology Terms
Boecker, Florian (2021-10-05)In the postgenomic era it is impossible to annotate the majority of new proteins in any other way than with computational methods. Our tool AHRD automatically annotates proteins with human readable descriptions and Gene ... -
AI Models for Modeling and Simulation of Clinical Studies for Alzheimer's and Parkinson's Disease
Sood, Meemansa (2023-08-14)Neurodegenerative diseases (NDDs) have a complex structure and most of them are untreatable that’s why more research studies undertake translational paths for getting better insights into prevention, early detection, and ... -
Ai-based, behavior dependent approaches for connectomic reconstruction of neuronal circuits
Schweihoff, Jens Florian (2022-03-24)Characterizing the functional architecture of neuronal circuits that underly complex behavior requires identifying active neuronal ensembles during behavioral expressions of interest. The recent development of light-induced, ... -
Das Aktinzytoskelett-Protein Myotilin: Analyse speziesspezifischer Isoformen, Lokalisation in Nicht-Muskelzellen und Phosphorylierung
Günther, Andrea Katharina (2009-03-27)Das Aktinzytoskelett-Protein Myotilin wurde zuerst in Muskelzellen beschrieben. Sein unikaler N-Terminus weist eine serinreiche Region auf. Bei verschiedenen Muskelkrankheiten wurden Myotilinmutationen identifiziert, die ... -
Aktivierung der Mikrotubuli - Nukleationsfunktion des γ-Tubulin-Ring Komplexes
Peter, Christoph Hanno (2022-02-14)Mikrotubuli (MT) sind ein wesentlicher Bestandteil des Cytoskelettes und ihre Struktur und Funktion in allen Eukaryoten hoch konserviert. Bei der Zellteilung sind MT essentiell für die Segregation der Chromatiden auf die ... -
Alkyne lipid probes and azide detection reagents for in vitro enzymatic assays and highly sensitive lipid imaging
Gäbler, Anne (2015-08-28)Click chemistry has emerged as a powerful tool for the sensitive and specific labeling of biomolecules in various applications. For the design of lipid probes, a small and non-interfering tag is important to prevent ... -
Allelopathic effects of bark phenols on epiphytic lichens
Koopmann, Ricarda (2005)Natural implications for plant growth are important for our understanding of vegetational zonation.
We evaluated allelopathic constraints of natural bark phenols by comparing field data collected from sites with ... -
The allosteric core region of the M2 muscarinic acetylcholine receptor: role for ligand selectivity and action
Chirinda, Brian (2015-09-23)Muscarinic acetylcholine receptors (mAChRs) are seven transmembrane domain-spanning proteins belonging to the family A of G protein-coupled receptors (GPCRs). In addition to the orthosteric binding site (i.e. the site where ... -
Allosterische Modulation der durch Acetylcholin und weitere Agonisten ausgelösten Aktivierung von muskarinischen M2-Rezeptoren
Schmalenbach, Caroline (2006)Acetylcholin ist der endogene Ligand an allen fünf Subtypen muskarinischer Acetylcholin-Rezeptoren. Zusätzlich zu der orthosterischen Bindungsstelle, an die z. B. Acetylcholin bindet, besitzen muskarinische Rezeptoren auch ... -
Altered signaling, but no cell fragility in mice lacking all type II keratin genes
Vijayaraj, Preethi (2008)Keratins are major cytoskeletal proteins of epithelia, organized in two large gene families of 28 (type I) and 26 (type II) members spanning 1.2 Mb and 0.68 Mb of genomic loci, respectively. Their expression is tightly ...