E-Dissertationen: Search
Now showing items 71-80 of 215
Molecular mechanisms underlying presynaptic plasticity: characterization of the RIM1α and SV2A interactome
(2015-02-11)
Synaptic plasticity encompasses various cellular mechanisms, which confer synapses the ability to react and adapt to ongoing changes in network activity. Some of the suggested mechanisms include remodelling and/or assembly ...
Semantic Interpretation of User Queries for Question Answering on Interlinked Data
(2015-01-29)
The Web of Data contains a wealth of knowledge belonging to a large number of domains. Retrieving data from such precious interlinked knowledge bases is an issue. By taking the structure of data into account, it is expected ...
Challenges of theoretical and numerical structure formation in a ΛCDM universe
(2015-06-22)
Systematic surveys of the extra-galactic sky have revealed the existence of large-scale structures in the Universe: the galaxy distribution is organized in a complex network of filaments surrounding underdense regions and ...
Galaxies in Milgromian Dynamics
(2015-02-04)
Since its first formulation in 1983, Milgromian dynamics (also known as modified Newtonian dynamics or MOND) has been very successful in predicting the gravitational potential of galaxies from the distribution of baryons ...
Distribution and genetic composition of carbapenem-resistance determinants in clinical Acinetobacter isolates – focus on carbapenem-hydrolysing β-lactamases
(2015-02-11)
Acinetobacter baumannii is of global concern in health-care facilities as it can easily thrive in the hospital environment and infections can be difficult to treat. Widespread multi-drug (MDR) resistance and a ...
Charakterisierung von Tumorstammzellen des Medulloblastoms und Analyse ihrer molekularen Regulation
(2015-01-08)
Das maligne Medulloblastom, welches aus unreifen neuralen Zellen des Kleinhirnes entsteht, zeigt eine zelluläre und molekulare Heterogenität. Die CSC (Cancer Stem Cell)-Hypothese soll zu einem besseren Verständnis der ...
The Foraminifera of the Zanzibar Archipelago: (Tanzania, East Africa)
(2015-01-08)
The Zanzibar Archipelago is the largest reef system in eastern Africa and represents the transition from the high-diversity region of the Asian Indo-Pacific to the cold-water areas of southern Africa. It is among the most ...
Therapeutically important enzymes with polar substrates or products: characterization by capillary electrophoresis and identification of inhibitors
(2015-01-15)
Enzymes are important drug targets, since they participate in many disease processes and can be inhibited by small drug molecules. In our research projects, a group of therapeutically important enzymes with polar substrates ...
Reverse genetics for Human Coronavirus NL63
(2015-01-13)
In 2004 a novel human coronavirus designated HCoV-NL63 was isolated in the Netherlands. The fact that it uses the same entry receptor as SARS-CoV could make HCoV-NL63 an important model for the identification of antiviral ......
Mathesis of star formation – from kpc to parsec scales
(2015-06-16)
In this thesis I present a series of studies aiming to understand the formation of stars from gas in the Milky Way. Generally speaking, I will progress from larger to smaller scales.
The kilo-parsec scale (1000 ...
The kilo-parsec scale (1000 ...