E-Dissertationen: Search
Now showing items 21-26 of 26
Mechanisms of memory consolidation: Analyzing the coordinated activity of concept neurons in the human medial temporal lobe during waking and sleep
(2018-12-11)
The aim of this thesis is to investigate the role of human concept neurons in memory consolidation during sleep. Memory consolidation is a process by which memories initially dependent on the hippocampus are transferred ...
Binding of cytohesin 2 to the plasma membrane and its relationship with the EGFR
(2018-11-06)
Eukaryotic cells are compartmentalized by lipid membranes to achieve the spatial separation of biological processes and signaling pathways. Controlled trafficking of proteins between these compartments as well as the ...
Role of the cannabinoid receptor 2 in the development of surgical neuropathic pain
(2018-12-12)
When normal nociceptive pain becomes chronic, it loses its protective function and causes a general pain hypersensitivity. Neuropathic pain is one type of chronic pain, which is caused by various diseases or physical injury ...
Influence of the St John´s wort extract Ze117 and selected ingredients on membrane fluidity and phospholipid composition in rat C6 glioblastoma cells
(2018-10-31)
Chronic stress has been recognized to represent a key factor for the development of depression. Among others cortisol has been described to mediate an adaptive effect on plasma membrane fluidity which may affect signal ...
Dualsterische Liganden, allosterische Agonisten und ein allosterischer Förderer der Agonist-Bindung und -Funktion: Modellgestützte Analysen ihrer Rezeptorinteraktionen, Signalweg-Aktivierungen und -Selektivitäten an Wildtyp und punktmutierten hM1-Rezeptoren in CHO-Zellen
(2018-05-24)
Dualsterische Hybridliganden, bestehend aus einem allosterischen und einem orthosterischen Baustein, die über eine Zwischenkette verbundenen sind, gelten als ideale Werkzeuge zur Entwicklung subtyp- und signalwegselektiver ...
The relevance of myeloid-derived suppressor cells during Litomosoides sigmodontis infection
(2018-05-23)
68 million people are infected with lymphatic filariasis (LF) in Sub-Saharan Africa, South-East Asia and South America, causing a major health problem with economic repercussions among the infected populations. This disease ......