E-Dissertationen: Search
Now showing items 3761-3770 of 4168
Biochemische Analyse der Interaktion von P2X4 und P2X7 und Charakterisierung von P2X7B und genetisch verlinkten P2X4/P2X7-Konkatameren
(2023-02-23)
Das übergeordnete Ziel meiner Arbeit war die Untersuchung der Interaktion von P2X7 und P2X4. Zur Identifikation von potenziellen Interaktionspartnern habe ich den P2X7-Rezeptors von Mensch und Ratten mit den weiteren ...
Untersuchung der mechanobiologisch gesteuerten Brustkrebszellinvasion mittels 3D Zellkulturmodellen
(2022-12-20)
Ein erster zentraler Schritt während der Metastasierung bei Brustkrebs ist die lokale Zerstörung der Basalmembran (BM), gefolgt von der Transmigration invasiver Zellen. Dieser Prozess ist in vivo schwierig zu visualisieren, ...
Novel aspects regarding structural variability in membrane protein families by the example of tetraspanins
(2022-11-16)
The work at hand focuses on structural variability in membrane protein families by the example of tetraspanins. The family of tetraspanins is found in almost all multicellular organisms and they play important roles in an ...
On a non-local free boundary problem modeling cell polarization
(2022-11-08)
The amplification of an external signal is a key step in direction sensing of biological cells, a process that contributes significantly in the regulation of cell shape. This thesis is concerned with a simple model for ...
Sheaves, Quasimaps, Maps, Covers
(2022-11-09)
Let $X$ be a smooth variety, let $S$ be a smooth surface, let $C_{g,N} rightarrow overline{M}_{g,N}$ be a universal curve over a moduli space of stable marked curves and let $(C,mathbf{x})$ be a marked nodal curve.
Aneignung und Beheimatung von Grundschulkindern in Bonner Stadtquartieren
(2023-03-27)
„Heimat“ verbinden viele Erwachsene mit dem Ort, an dem sie als Kind gelebt haben und aufgewachsen sind (IFD ALLENSBACH 2018, S. 12), und die Kindheit gilt als die Phase im Leben, in der räumliche und soziale Stabilität ...
Analysis of Elliptic and Parabolic Partial Differential Equations Based on Carleson Measures
(2022-09-02)
This thesis proposes a new technique to analyze nonlinear elliptic and parabolic partial differential equations by exploiting the knowledge generated by the associated Carleson measure characterization of admissible data ...
Molecular diversity in early stage high-mass protostars
(2022-11-30)
During star formation, the molecular gas undergoes significant chemical evolution with the emergence of dense cores harboring hot cores and hot corinos, rich in complex organic molecules (COMs). The formation pathways, ...
Unraveling Molecular Gas Conditions across Nearby Galaxies with CO Isotopologues
(2022-12-07)
In general, we associate large spatial scales, heavy massive objects, and great distances with the scientific study of Astronomy. However, in this thesis, we study the tiny hydrogen molecule, H2, which populates ......
From Density Functional Theory to Tight Binding: Development of Robust and Efficient Quantum Chemistry Methods
(2022-12-07)
The main topics of this thesis are efficient quantum chemical methods, their development, and the verification using existing and newly devised benchmark sets. The spectrum of quantum chemical methods discussed here includes ...