E-Dissertationen: Suche
Anzeige der Dokumente 581-590 von 627
Synthesis, optimization, and characterization of chromen-4-one and 1,7-phenanthroline derivatives as ligands for the orphan G protein-coupled receptors 35 and 84
(2021-06-21)
G protein-coupled receptors (GPCRs) are ideal drug targets. Their characteristic tissue distribution, marked ligand specificity, and their roles in countless (patho)physiological processes are being exploited by more than ...
Establishment of a Split-Combine Cell-SELEX method for Identification of Nucleobase-Modified Aptamers with Specific Binding to Androgen-independent Prostate Cancer Cells
(2023-09-11)
(noch nicht zugänglich / not yet accessible)
Diastereoselektive Titanocen(III)-Katalyse – Synthese benzylischer 1,3-Dioxolane und 1,3-Oxazolidine
(2023-09-14)
(noch nicht zugänglich / not yet accessible)
Dry powder inhaler: Interaction between drug particles and the device
(2023-09-28)
(noch nicht zugänglich / not yet accessible)
Tool Compounds to Study Proteolytic Events: Development of von Hippel-Lindau (VHL) Ligands and Combinatorial Generation of Serine Protease Inhibitors
(2023-10-04)
(noch nicht zugänglich / not yet accessible)
Drug nanocrystals for the treatment of inflammatory bowel diseases (IBD)
(2022-12-08)
(noch nicht zugänglich / not yet accessible)
Regulation of inhibitory synaptic connections and distal neuronal complexity by the Ste20-like kinase Slk
(2022-11-28)
(noch nicht zugänglich / not yet accessible)
On the importance of meteorological parameters in processes affecting the chemical composition of the tropsphere
(2022-12-22)
Investigating the interaction of meteorology and chemistry in the troposphere is important for the identification of the processes which drive the evolution of tropospheric composition in a changing climate. It does not ...
I) Characterization of LytR-CpsA-Psr enzymes and their role in Staphylococcus aureus cell wall formation
II) Elucidating the mode of action of Cacaoidin, a novel class V lantibiotic
(2022-04-04)
Antibiotic resistance poses a serious threat to human health, demanding for the discovery and development of antibiotics with resistance-breaking properties. New antibiotics should be sought with the focus on novel chemistry ...
Design and Synthesis of A2B- and Dual-Acting A2A/A2B Adenosine Receptor Antagonists
(2020-10-27)
A2A and A2B adenosine receptors (ARs) are novel drug targets in cancer (immuno)therapy. Activation of A2AARs expressed on the surface of many immune cells such as T-lymphocytes and natural ...