E-Dissertationen: Search
Now showing items 81-85 of 85
Obesity impairs virus-specific memory CD8+ T cell signalling and function
(2024-04-11)
The main function of the immune system is to protect the host against invading pathogens. Immunological memory is formed after a primary infection and serves to provide protection in a fast and vigorous manner upon secondary ...
Pilzkontaminationen in Korneatransplantaten: Effektivität antimykotischer Medienzusätze und Anwendbarkeit molekularbiologischer Detektionsmethoden
(2023-10-16)
Postoperative Infektionen stellen eine schwerwiegende Komplikationen nach Korneatransplantation dar. In den letzten Jahren wurde ein Anstieg der Inzidenz von Pilzinfektionen nach Keratoplastik festgestellt. Aktuell werden ...
Impact of aging and enriched environment on α-synuclein propagation
(2022-04-06)
Parkinson's disease (PD) is the second most common neurodegenerative disease. The prevalence of sporadic PD results from a complex interaction of demographic, genetic, and environmental factors. Age is one of the strongest ...
Protein markers of inflammation and ageing in a European multi-centre dementia cohort
(2024-03-01)
Inflammation plays a key role in Alzheimerʼs disease (AD) progression. Microglia in the AD brain are exposed to pathological amyloid β (Aβ42) and tau peptide aggregates, resulting in the NLRP3 inflammasome activation ...
Organization principles of thalamocortical input onto deep-layer inhibitory neurons of the barrel cortex
(2024-02-28)
Thalamus functions as the main route by which incoming sensory information reaches the cerebral cortex. Thalamic nuclei will receive input from the sensory receptors in the periphery and relay it to different areas in the ...