E-Dissertationen: Search
Now showing items 71-80 of 85
Role of GluA2-containing AMPARs in Oligodendrocyte Lineage Cells
(2024-01-30)
Oligodendrocytes precursor cells (OPC), also called NG2 cells, proliferate or differentiate into myelin-producing oligodendrocytes throughout life. Myelination depends on neuronal activity. Although NG2 cells receive ...
Chronic Helminth Infection Ameliorates Colitis via ***** regeneration program
(2022-03-07)
(noch nicht zugänglich / not yet accessible)
Physical activity and fitness for healthy ageing
(2024-02-19)
The proportion of individuals suffering from age-associated noncommunicable diseases is expected to rise rapidly in the next decades. To maintain health, well-being and socioeconomic stability in an ageing society, identifying ...
Sphingosine-1-phosphate receptor 3 signaling is a critical modulator of stroke outcome
(2022-08-29)
Stroke is a leading cause of long-term disability worldwide. Its highly complex pathogenesis is characterized by a deleterious cycle of vascular dysfunction and inflammation. Recently, the bioactive phospholipid ......
Recognition of orthoflaviviral RNA in mosquitoes and viral countermeasures
(2024-02-26)
Various infectious diseases are caused by mosquito-borne orthoflaviviruses affecting people worldwide. Efficient transmission of these viruses highly depends on the pathogen’s ability to overcome the host immune system. ...
The Role of High-Salt Diet on Melanoma Growth
(2024-03-04)
Cutaneous melanoma is one of the most aggressive cancer types in Western countries with a rising incidence over the last decades. Treatment of early-diagnosed melanoma constitutes a good survival rate and recovery. However, ...
Immune activation by DNA sensors in ANCA associated vasculitis
(2024-03-04)
Anti-neutrophilic cytoplasmatic antibody (ANCA) associated vasculitis (AAV) is a group of rare inflammatory autoimmune diseases primarily affecting the small vessels of kidney and lung. Current treatment options mainly ...
Influence of the Fatty Acid Saturation Levels on Inflammatory Signalling in Melanoma Cells
(2023-09-11)
Due to their rapid proliferation, tumour cells have an enhanced demand for lipids. Therefore, increased lipogenesis is considered as a hallmark of cancer. In melanoma, the lineage addiction oncogene MITF regulates the ...
Einfluss der Cyclin-abhängigen Kinase 5 auf die Expression des Programmed Cell Death Ligand 1 in murinen Pankreaskarzinomen im Vergleich verschiedener Analysemethoden
(2023-03-23)
Einleitung: Programmed Cell Death Ligand 1 (PD-L1) ist ein immuninhibitorisches Molekül, das für gewöhnlich von bestimmten Immunzellen oder dendritischen Zellen exprimiert wird. Auch verschiedene Tumoren ...
Validation, determinants and impact of medication use
(2024-04-02)
In recent decades, global medication consumption has increased substantially due to an aging population and more emphasis on preventative treatment. As medication use increases, concerns naturally arise regarding the ...