Faculties of University Bonn: Search
Now showing items 11-20 of 435
Einsatz der HIV-Postexpositionsprophylaxe im klinischen Alltag am Beispiel der Bonner HIV-Ambulanz
(2021-01-26)
Hintergrund: Die HIV Postexpositionsprophylaxe (PEP) ist etablierter und empfohlener Standard nach beruflicher Exposition (BE) oder nicht-beruflicher HIV-Exposition (NBE, sexuell). Publizierte Daten zur Expositionsart, ...
Synthese und Reaktionen von phosphorfunktionalisierten 1,3-Dithiol-2-thionen
(2021-01-05)
Die Dissertation "Synthese und Reaktionen von phosphorfunktionalisierten 1,3-Dithiol-2-thionen" beschreibt die Darstellung von tricyclischen 1,4-Dihydro-1,4-diphosphininen, die 1,3-Dithiol-2-thion-Einheiten tragen. Zugleich ...
Biochemical characterization of the human Cyclin-dependent kinases Cdk7 and Cdk10
(2021-08-13)
Protein kinases comprise a large superfamily of enzymes regulating a plethora of cellular processes. Dysregulation of protein kinases, such as loss of activity, hyperactivity or mislocalisation, is often accompanied with ...
Development of Computational Methods for Rationalizing Chemical Lead Optimization and Compound Design
(2021-09-22)
Chemical lead optimization (LO) plays an important role in pharmaceutical drug discovery. It represents a highly complex multi-objective process, in which the ultimate goal is to identify a suitable candidate molecule that ...
Role of innate lymphoid cells in type 1-dominated experimental Plasmodium berghei ANKA and type 2-dominated Litomosoides sigmodontis infection
(2021-10-27)
Malaria and filariasis remain among the biggest health problems in the tropics and subtropics, especially in Africa, and in the case of malaria among the ten most frequent causes of death. The parasites that cause malaria ......
The Hubbard Model on the Honeycomb Lattice with Hybrid Monte Carlo
(2021-11-09)
We take advantage of recent improvements in the grand canonical Hybrid Monte Carlo (HMC) algorithm, to perform a precision study of the single-particle gap in the hexagonal Hubbard model, with on-site electron-electron ...
Supersymmetric methods in random matrix theory
(2021-12-02)
Randomness and chaos are key ingredients in the description of nature and are therefore central elements in mathematics and physics. A conducting metal becomes an insulator if there are enough random defects in its structure. ...
Single cell visual psychophysics
(2021-10-05)
On the one hand, the eye is the human being’s window to the world. On the other hand the eye is a window to the human brain enabling noninvasive and in vivo assessment of nervous tissue. With adaptive optics scanning laser ...
On the Localisation and Reconstruction of Structural Model Errors in Dynamic Systems
(2021-09-02)
Pursuing a deeper understanding of the behaviour of dynamic systems is a main task of modern sciences, from accurate weather forecasts to precise drug delivery, from electrical engineering to cell biology and the very ......
Three Essays on the Interconnectedness of Labor Markets and Household Finance
(2021-07-13)
This dissertation consists of three self-contained essays that investigate the interconnectedness of labor markets and household finance. The first two chapters focus on differences in workers' labor market experience and ...