Medizinische Fakultät: Medizinische Fakultät: Neuzugänge
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Einfluss von hypoxisch-ischämischem Hirnschaden auf die Neurogenese und das strukturelle sowie funktionelle Outcome im Rattenmodell
(2025-08-15)<strong>Hintergrund und Zielsetzung:</strong><br/> Die hypoxisch-ischämische Enzephalopathie (HIE) bei Neugeborenen entsteht durch eine mangelhafte Versorgung des Gehirns mit Sauerstoff und Nährstoffen rund um die Geburt. ... -
Ärztliches Verordnungsverhalten von Laboranalysen am Beispiel des Serummagnesiums: Eine Vorher-/Nachher-Studie mit unterbrochenen Zeitreihen
(2025-08-13)Die strukturellen Einflüsse auf die Entscheidungsfindung in der medizinischen Versorgung wurden bislang nur unzureichend untersucht. <br/> Die durchgeführte Studie widmet sich einem Teilaspekt dieser Problemstellung, indem ... -
33/m: Komplettierung des Impfstatus vor Praktikum in Kindertagesstätte: Vorbereitung auf die Facharztprüfung: Fall 52
(2024-07-11)<strong>Prüfungssimulation</strong><br /> <strong><em>Fallschilderung</strong></em><br /> Ein 33-jähriger Student des Fachs Kindheitspädagogik möchte in 6 Wochen sein erstes Praktikum in einer Kindertagesstätte ... -
Mouse models of type I interferonopathies
(2024-12-16)Type I interferonopathies are severe monogenic diseases caused by mutations that result in chronically upregulated production of type I interferon. They present with a broad variety of symptoms, the mechanisms of which are ... -
IDEAL–compliant implementation of the Dexter® surgical robot in cholecystectomy: A comprehensive framework and clinical outcomes
(2024-12-30)<strong>Objectives:</strong> The integration of advanced technologies is transforming surgical practice, particularly through robotic systems. This study presents the early clinical implementation of the Dexter<sup>®</sup> ... -
Longitudinal Study of SARS-CoV-2 Vaccinations and Infections in Patients with Gastrointestinal Cancer: Stabilizing Immune Responses and Neutralizing Emerging Variants with Variant-Adapted Antigen Exposures
(2024-12-19)This longitudinal study examined how active gastrointestinal (GI) cancer types affect immune responses to SARS-CoV-2, focusing on the ability to neutralize the Omicron variants. Patients with GI cancer (<em>n</em> = 168) ... -
Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma
(2023-10-17)<strong>Background & Aims:</strong> Vaccination with tumor-associated antigen-pulsed dendritic cells leads to specific T-cell response against hepato-cellular carcinoma. However, clinical response has been shown to be ... -
Epidemiology and outcomes of vancomycin-resistant enterococcus infections: A systematic review and meta-analysis
(2023-09-19)Vancomycin-resistant enterococci (VRE) cause many infections in the healthcare context. Knowledge regarding the epidemiology and burden of VRE infections, however, remains fragmented. We aimed to summarize recent studies ... -
Evaluating AI Courses: A Valid and Reliable Instrument for Assessing Artificial-Intelligence Learning through Comparative Self-Assessment
(2023-09-26)A growing number of courses seek to increase the basic artificial-intelligence skills ("AI literacy") of their participants. At this time, there is no valid and reliable measurement tool that can be used to assess AI-learning ... -
Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years
(2024-04-30)<strong>PURPOSE.</strong> To longitudinally assess the impact of high-risk structural biomarkers for natural disease progression in non-exudative age-related macular degeneration (AMD) on spatially resolved mesopic and ... -
Key factors for sustainable working conditions in emergency departments: An EUSEM-initiated, Europe-wide consensus survey
(2025-02)<em>Background and importance</em> Modern emergency medicine (EM) is a complex, demanding, and occasionally stressful field of work. Working conditions, provider well-being, and associated health and performance outcomes ... -
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function
(2024-04-29)Promoting brown adipose tissue (BAT) activity innovatively targetsobesity and metabolic disease. While thermogenic activation of BAT is wellunderstood, the rheostatic regulation of BAT to avoid excessive energy dissipation ... -
The Spectrum of Functional, Structural and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report
(2025-02-03)<em><strong>Introduction:</strong></em> There is an unmet medical need for therapies in intermediate age-related macular degeneration (iAMD). The prospective European multi-center cohort study MACUSTAR validates structural, ... -
TFAP2E is implicated in central nervous system, orofacial and maxillofacial anomalies
(2024-12-23)<strong>Background</strong> Previous studies in mouse, <em>Xenopus</em> and zebrafish embryos show strong <em>tfap2e</em> expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in ... -
Ergebnisse von abdomino-thorakalen Eingriffen am Lymphgefäßsystem zur Behandlung traumatischer und nicht-traumatischer Lymphleckagen
(2025-08-11)<strong>Hintergrund:</strong><br /> Chylöse Ergüsse wie Chylothorax oder Chylaszites stellen seltene, aber schwerwiegende Krankheitsbilder dar, die häufig mit hoher Morbidität und Mortalität einhergehen. Ziel dieser Studie ... -
Across Diagnostic Boundaries: Genetic Variants for Neuropsychiatric Disorders and their Association with Human Brain Structure
(2025-08-11)With the advances in genome-wide association studies (GWAS), hundreds of genetic variants have been identified for neuropsychiatric disorders. Strikingly, many of these genetic variants showed complex associations across ... -
NIS-Seq enables cell-type-agnostic optical perturbation screening
(2024-12-19)Optical pooled screening offers a broader-scale alternative to enrichment-based perturbation screening, using fluorescence microscopy to correlate phenotypes and perturbations across single cells. Previous methods work ... -
Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei
(2024-12-10)<strong>Background:</strong> <em>Mansonella perstans</em> is transmitted by <em>Culicoides</em> species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis ... -
Comparative Analysis of Shear Bond Strength in Orthodontic Brackets Between Milled and 3D-Printed Definitive CAD/CAM Restorations
(2024-10-18)<strong>Objective:</strong> The objective of this study was to evaluate the effect of different surface treatment methods on the shear bond strength (SBS) of metal brackets bonded to two types of CAD/CAM composite restorations: ... -
Schistosomiasis–Microbiota Interactions: A Systematic Review and Meta-Analysis
(2024-10-16)Introduction: Schistosomiasis, a tropical disease affecting humans and animals, affected 251.4 million people in 2021. <em>Schistosoma mansoni, S. haematobium, S. intercalatum</em>, and <em>S. japonicum</em> are primary ...
