The Faculty of Mathematics and Natural Sciences: Mathematisch-Naturwissenschaftliche Fakultät: Recent submissions
Now showing items 81-100 of 4811
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Studies of the Envelopes of Evolved Stars using Millimetre and Submillimetre Spectroscopy
(2025-06-03)Asymptotic giant branch (AGB) stars are low- to intermediate-mass stars at the end of their life. At this stage of stellar evolution, these objects shed large amounts of matter in the form of gas and dust, forming a ... -
Identification of compensatory mechanisms and disease pathways in mitochondrial disease and synucleinopathy
(2025-06-02)Mitochondria play vital roles in a variety of processes such as cellular metabolism, intracellular signalling and cell death. Defects in mitochondria can lead to inherited metabolic disorders and neurodegenerative diseases. ... -
Strong coupling between WS2 monolayer excitons and a hybrid plasmon polariton at room temperature
(2024-04-15)Light–matter interactions between plasmonic and excitonic modes have attracted considerable interest in recent years. A major challenge in achieving strong coupling is the identification of suitable metallic nanostructures ... -
Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations
(2024-03-12)Toxicological studies are a part of the drug development process and the preclinical stages, for which suitable vehicles ensuring easy and safe administration are crucial. However, poor aqueous solubility of drugs complicates ... -
Design and development of probes for studying cannabinoid and related orphan G protein-coupled receptors and their signaling
(2025-05-27)G protein-coupled receptors (GPCRs) are the largest family of human membrane proteins and represent one of the most important classes of pharmacological targets for drugs. Among these, the cannabinoid (CB)receptor subtypes ... -
Modelling Molecular Gas and Its Tracers Across Cosmic Time
(2025-05-27)Our understanding of the distant Universe and the processes governing galaxy formation and evolution largely stems from observing the light from stars and its interaction with the material surrounding them. However, an ... -
Glucose-induced activation of Tas1R3 disrupts calcium signaling and macrophage functionality
(2025-05-22)The incidence of <em>diabetes mellitus</em> has risen alarmingly in recent years, becoming one of the leading causes of death worldwide. The disease is characterized by hyperglycemia, increased blood glucose levels, and ... -
Mechanism of Action Analyses of Cell Wall Synthesis Inhibitors and Lipophilic Derivatives with Enhanced Antibiotic Activity
(2025-05-21)(noch nicht zugänglich / not yet accessible) -
Investigation of β-arrestin 2 recruitment, downstream signal transduction and lateral mobility of adenosine A1 receptor after treatment with valerian extract Ze 911
(2025-05-21)Sleep is a complex physiological process with a variety of molecules involved. Even though a lot of research and progress has been made until today, the exact underlying mechanism still eludes us. Many people must deal ... -
Context-aware Deep Learning in Medical Image Analysis
(2025-05-13)Deep Learning (DL) has demonstrated outstanding performance in the area of medical image analysis, with models achieving levels of accuracy that may exceed those of human experts across various applications. This highlights ... -
Dense Gas and Star Formation from the Milky Way to Nearby Galaxies
(2025-05-12)Galaxies are the building blocks of the universe, which come in different sizes and shapes. Driven by dark matter, galaxies can interact and merge to form bigger galaxies across cosmic time. Across the cosmos, there are ... -
Reduced Costs for Vehicle Routing and General Mixed-Integer Programs
(2025-05-09)Mixed-integer linear programming is a powerful tool for modeling combinatorial optimization problems in a standardized way. Sophisticated solvers that calculate optimal solutions for these programs consist of dozens of ... -
Investigating the Conformational Landscape of Cas13a
(2025-05-06)Bacteria and bacteriophages are in a constant arms race to develop strategies to coexist. One adaptive defense system, which bacteria and archaea have developed against phages is the CRISPR-Cas (Clustered Regularly Interspaced ... -
Effects of structural differences of biflavonoids from fruits of the Brazilian peppertree (Schinus terebinthifolius Raddi) on food-associated microorganisms
(2025-05-05)Economic, health, or sensory aspects are affected by microbial contamination of food. The preservation of food is crucial for ensuring food safety and reducing economic losses. With increasing resistance, allergies, and ... -
Omics-driven Drug Repurposing and Treatment Assessment in Human Viral Diseases
(2025-05-02)In this cumulative thesis, I present my research on transcriptomic-based drug repurposing in human viral infections describing an optimized workflow for drug prediction, <em>in vitro</em> validation and <em>in vivo</em> ... -
Economic geographies of large-scale renewable energies development in Kenya: Financing, governance and infrastructures
(2025-05-02)Energy transition theories and studies have made important contributions to our knowledge of the challenges and possibilities for achieving sustainable energy transition and more sustainable societies. However, this body ... -
A probabilistic solution to geophysical inverse problems in complex variables and its application to complex resistivity imaging
(2024-02-01)We introduce a novel probabilistic framework for the solution of non-linear geophysical inverse problems in complex variables. By using complex probability distributions, this approach can simultaneously account for ... -
Ubiquitous biosynthesis of nano selenium in plants
(2025-04-28)Selenium, an essential trace element of the chalcogenide group, is involved in a variety of physiological processes and plays a crucial role in human health. The impact of selenium on the incidence and prognosis of many ... -
On the X-ray Emission of Massive Binary Stars
(2025-04-28)This thesis is dedicated to the theoretical investigation of massive binary systems consisting of a normal star and a neutron star or black hole as a companion. The initial focus lies on the mass transfer from an evolved ... -
Exploring the mechanisms of chlamydial cell division, peptidoglycan turnover, and persistence
(2025-04-29)(noch nicht zugänglich / not yet accessible)
