E-Dissertationen: Search
Now showing items 11-20 of 66
Interaktionen und Signalweiterleitung von Dectin-1 in dendritischen, tolerogenen dendritischen Zellen sowie Transfektionsmodellen
(2018-06-06)
Dectin-1 ist ein Musterkennungrezeptor auf Zellen des Immunsystem, welcher beta-Glukane in der Zellwand von pathogenen Pilzen erkennen und über Sykvermittelte Signalwege sowohl Mechanismen des angeborenen, als auch des ......
Dectin-1 is a pattern-recognition receptor on cells of the immune system, which recognizes beta-glucans in the cell wall of pathogenic fungi and subsequently induces innate and adaptive immune responses via Syk-mediated ......
Dectin-1 is a pattern-recognition receptor on cells of the immune system, which recognizes beta-glucans in the cell wall of pathogenic fungi and subsequently induces innate and adaptive immune responses via Syk-mediated ......
The glmS ribozyme is an antibacterial target: Mode of action analysis, investigation of potential metabolite analogs and characterization of glmS ribozyme variants of human pathogens
(2018-05-22)
Bacteria increasingly develop resistances to the known antibiotics, this threatens human health. Thus, novel antibiotics are urgently needed. The currently used antibiotics mainly target five bacterial processes and are ...
From glycosidase activity profiling to inhibitor discovery in the plant pathogen Pseudomonas syringae
(2018-05-25)
Retaining glycosidases are important in plants for various biological processes. Plant genomes encode for more than 200 retaining glycosidases but the physiological roles and activities of many remain poorly understood. ...
Untersuchungen zur Erweiterung des Substratspektrums von Gluconobacter oxydans
(2018-01-29)
Die vorliegende Arbeit befasste sich mit einem bislang weitgehend unbearbeiteten Bereich der Stammoptimierung des biotechnologisch und industriell wichtigen Essigsäurebakteriums Gluconobacter oxydans. Dieser Organismus ist ......
Characterization of the structural-functional impact of heterozygous missense mutations in genes of the blood coagulation factor XIII that cause mild Factor XIII deficiency
(2018-01-04)
The coagulation Factor XIII is a key player in hemostasis that is responsible for the last step of the coagulation cascade in which it covalently cross-links preformed fibrin clots to make them resistant to premature ......
Examining the Retention and Digestion of Functional Kleptoplasts in Solar-Powered Sea Slugs
(2018-01-18)
Sacoglossan sea slugs are the only metazoans known to sequester and retain functional chloroplasts within their digestive gland tubules, a process known as functional kleptoplasty. This ability coincides with the capacity ...
Characterization of the transcription factor ANAC058 and its role in suberin regulation
(2018-08-28)
The hydrophobic polymer suberin is present in plant roots. Its biosynthesis and composition is of importance for tolerance towards environmental stresses. In the model plant Arabidopsis thaliana transcription factors ......
Analysis of SCF+ cardiac cells in mice
(2018-08-28)
Proper regulation of c-kit receptor tyrosine kinase by its ligand, Stem Cell Factor (SCF), is essential for survival, growth, migration and differentiation of many types of stem/progenitor cells. However, its role in the ...
Ecological and host behavioural aspects of parasite dispersal in a simple and a complex host–parasite system
(2018-09-28)
If one is to understand how parasitic diseases spread within and among host populations, one has to take into account characteristics of the given parasite species, the host as well as of their common environment. To what ...
The role of the endocannabinoid receptor CB2 in a mouse model of Alzheimer's disease
(2018-09-26)
Over the past years, an important role of the cannabinoid receptor 2 (CB2) has been implicated in several neurological and immunological conditions, such as experimental autoimmune encephalitis, stroke, memory, neuropathic ......