E-Dissertationen: Search
Now showing items 3711-3720 of 4071
The interplay of differentially γ-carboxylated vitamin K dependent proteins constitute variable VKCFD1 phenotypes
(2021-11-18)
Vitamin K dependent coagulation factor deficiency type 1 (VKCFD1) is a rare hereditary bleeding disorder caused by mutations in γ-Glutamyl carboxylase (GGCX). VKCFD1 patients are treated with high dose of vitamin K, ...
Detection of Legionella pneumophila and Pseudomonas aeruginosa and biofilm experiments in four different cooling towers (construction and biocide treatment) and evaluation of IDEXX most probable number methods in industrial water samples
(2021-11-30)
The responsible maintenance of evaporative cooling systems is an essential element in reducing the risk of the environmental dispersion of legionellae and Legionnaires’ disease outbreaks. In Germany, the 42nd Ordinance ......
Studien zur Untersuchung der Interaktion von Häm und Hämopexin
(2023-05-24)
In hämolytischen Zuständen lysieren Erythrocyten, es tritt Hämoglobin aus und dieses setzt Häm frei. Das Eisenion von Häm kann an Fenton-artigen Reaktionen teilnehmen, die reaktive Sauerstoffspezies produzieren. Diese ...
Morphological evolution and phylogeny of millipedes (Diplopoda)
(2023-05-25)
Millipedes (Diplopoda) count more than 12,000 described species and play, probably since more than 400 million years, a fundamental role as detritivores in terrestrial ecosystems. Despite their great diversity and ecological ...
Glial dysfunction in the pathology of temporal lobe epilepsy
(2023-05-30)
Epilepsy is a common neurological disorder characterized by periods of transient abnormal electrical brain activity, which manifests as behavioral symptoms known as epileptic seizures. Despite intense research, the underlying ...
Untersuchung der molekularen Mechanismen einer Thrombozytenaktivierung durch Karzinomzellen und die Rolle des Tumormarkers MACC1 in diesem Prozess
(2023-05-31)
Die Interaktion der Tumorzellen mit Thrombozyten und die damit einhergehende Aktivierung ist ein Schlüsselfaktor der Tumormetastasierung. Die molekularen Mechanismen einer Thrombozytenaktivierung durch Tumore können sehr ...
Assays and ligands for underexplored membrane proteins with potential as future drug targets
(2023-05-30)
(noch nicht zugänglich / not yet accessible)
Polynomial Inflation and Its Aftermath
(2022-11-10)
Cosmic inflation elegantly resolves problems in the standard cosmology. The most simple inflationary theory invokes a single scalar field phi, slowly rolling down from a flat potential of a monomial form. However latest ...
Geometry and derived categories of holomorphic symplectic manifolds
(2022-12-02)
In this thesis we study various aspects of hyper-Kähler manifolds and abelian varieties such as their derived categories, sheaves, cycles, and topology. The thesis consists of six parts.
The first part is mostly ...
The first part is mostly ...
(Patho)physiologische Rolle des Endocannabinoids Anandamid bei der bronchialen Tonusregulation
(2022-12-12)
Asthma und COPD gehören zu den häufigsten chronischen Erkrankungen und sind Hauptursachen für Morbidität und Mortalität bei Kindern und Erwachsenen weltweit. Diese obstruktiven Lungenerkrankungen sind durch einen erhöhten ...