E-Dissertationen: Search
Now showing items 31-40 of 165
Theoretical Interpretation of Experimental Data from Direct Dark Matter Detection
(2007)
Weakly Interacting Massive Particles (WIMPs) are one of the leading candidates for Dark Matter. Currently, the most promising method to detect many difeerent WIMP candidates is the direct detection of the recoil energy ...
Effects of transgenic overexpression of polysialyltransferase (PST) on myelination and impacts of increased sulfatide accumulation in arylsulfatase A deficient mice and its relevance to human metachromatic leukodystrophy
(2007)
The process of oligodendrocyte differentiation and myelination involves downregulation, biosynthesis and degradation of various lipids, proteins and carbohydrates. Alterations in these metabolic pathways can lead to ...
Therapy Approach of Neurodegenerative Disorders by Bone Marrow Stem Cells
(2007)
Multiple Sclerosis and cerebral ischemia are severe neurodegenerative diseases. Treatment in both cases is inadequate as drug delivery to the central nervous system (CNS) represents a difficulty due to the presence of the ...
Performance Analysis and Characterisation of a new Magneto-Electrical Measurement System for Electrical Conductivity Imaging
(2007)
An often used proxy in hydrogeology is the electrical condutctivity distributioni to study flow and transport of groundwater in soil. In order to map the electrical conductivity distribution of soil columns (length 0.5 m ...
Saposin B und D: Heterologe Expression in Pichia pastoris und biophysikalische Charakterisierung
(2007)
Die vier Saposine (Saps) A-D sind kleine, enzymatisch inaktive Glykoproteine, die in Lysosomen lokalisiert sind. Trotz ihrer hohen Sequenzhomologie zeigen sie als membranaktive, wasserlösliche Lipidbindungs- und Transferproteine ...
Orientation and Search Strategies of Desert Arthropods: Path Integration Models and Experiments with Desert Ants, Cataglyphis fortis (Forel 1902)
(2007)
Path integration enables desert arthropods to find back to their nest on the shortest track from any position. To perform path integration successfully, speeds and turning angles along the preceding outbound path have to ...
Molekulare Basis der Aktivierung und Modulation des P2Y2-Nukleotid-Rezeptors
(2007)
Der P2Y2-Rezeptor wird durch die physiologischen Nukleotide ATP und UTP aktiviert und löst eine Signalübertragung über die Phospholipase Cß und Inositol-1,4,5-trisphosphat aus, die schließlich zu intrazellulären ...
Untersuchungen zur Biosynthese und Funktion von alpha-hydroxylierten Sphingolipiden anhand von Mausmodellen
(2007)
Zur Überprüfung der Funktion der α-hydroxylierten Sphingolipide wurde in der vorliegenden Arbeit eine Mausmutante generiert, die defizient für das Enzym FA2H ist, welches für die α-Hydroxylierung verantwortlich gemacht ...
Synthese neuer, funktionalisierter BODIPY-Fluorophore zur Fluoreszenzmarkierung von Membranrezeptor-Liganden
(2007)
Die Verwendung von fluoreszenzmarkierten Strukturen bei der Untersuchung von biologischen Zielmolekülen stellt eine wertvolle Alternative zu Radioligand-bindungsstudien dar. Um diese Methoden anwenden zu können, bedarf es ...
Floodplain wetland-river flow synergy in the White Volta River basin, Ghana
(2007)
The Upper East Region of Ghana is characterized by an unreliable mono-modal rainfall pattern making rain-fed agriculture a risky business. Therefore, farmers along the White Volta River cultivate on the floodplain to make ...