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Fernmetastasierte neuroendokrine Tumoren des Pankreas: Ansprechen auf Radiopeptidtherapie mit 177Lu-DOTA-Octreotat
(2020-05-28)
Neuroendokrine Tumoren des Pankreas sind eine klinisch seltene Tumorentität mit einer jährlichen Inzidenz von < 1 pro 100.000. Bei Diagnosestellung können 60-80 % der P-NET metastasiert sein. Die Therapie von lokal ...
Function and diversity of myeloid cells during chronic inflammation in non-lymphoid organs
(2020-03-10)
Different immune cells play a major role in maintaining tissue homeostasis, tissue repair but also in inflammation. Tissue integrity is mainly controlled by tissue regulatory T cells (Tregs), type 2 innate ...
Essential and complementary function of dendritic cell subsets during immunotherapy
(2020-03-11)
T lymphocytes are critical components of the adaptive immune system that protects us against a variety of infections. However, during chronic infections such as with HIV, HCV and HBV as well as cancers, T cells become ...
Individual and organizational determinants of patient participation in multidisciplinary tumor conferences
(2021-07-09)
Background: Patient participation in multidisciplinary tumor conferences (MTCpp) is a new healthcare reality. Initial knowledge exists concerning risks and benefits for patients and providers. It is also ...
Investigation of Heat Shock Protein 70 and Toll-like Receptor 4 functions during inflammation reaction by mechanical compression in human periodontal ligament cells
(2021-06-24)
Biomechanical forces exerted during treatment with orthodontic appliances cause tensile and compressive strain within the periodontal ligament (PDL) of affected teeth followed by ischemia on the compression side. Further, ...
Experimenteller Vergleich von Folienmaterial für die Herstellung von kieferorthopädischen Alignern nach einer DIN-Ringversuchsvorschrift
(2020-11-05)
In den letzten Jahren hat in der Kieferorthopädie zunehmend die Therapie mit Alignern an Bedeutung gewonnen. Dies ist für die Patienten eine sehr attraktive Behandlungsalternative, da sie nahezu unsichtbar geschieht und ...
Werkstoffwissenschaftliche Untersuchung eines gefüllten, matrixmodifizierten zahnärztlichen Komposits
(2021-02-18)
Zielsetzung: Ziel dieser Studie war es, ein gefülltes Komposit zu bewerten, das auf der Matrixmodifikation eines konventionellen nanogefüllten Komposits basierte. Untersucht wurden der Umwandlungsgrad (DC ...
Characterization of the pro-inflammatory activity of short-chain fatty acids (SCFAs)
(2021-10-13)
Short-chain fatty acids (SCFAs), which are mainly derived from microbial fermentation of dietary fibres, have been considered to be beneficial to gut health for decades. Recently, a few of studies reported that some patients ...
Biomarkers and Correlates of Aging
(2021-10-19)
The rapid aging of the global population, often accompanied by disabilities and various age-related diseases, is becoming a major public health burden (WHO 2015). Stimulating healthy aging is therefore of tremendous ...
Functional and cellular heterogeneity of the myeloid cell system
(2020-11-09)
Cells of the myeloid lineage form the innate part of the immune system and are characterized by a high level of functional plasticity, which is required to address the diverse set of functions of these mononuclear cells. ...