Faculties of University Bonn: Fakultäten der Universität Bonn: Recent submissions
Now showing items 221-240 of 9523
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Prevalence and determinants of subretinal drusenoid deposits in patients' first-degree relatives
(2025-07-04)<strong>Purpose:</strong> Subretinal drusenoid deposits (SDDs) are distinct extracellular alteration anterior to the retinal pigment epithelium (RPE). Given their commonly uniform phenotype, a hereditary predisposition ... -
Die Rolle des P2Y12-Rezeptors in adipozytärem Gewebe
(2025-07-04)In dieser Studie konnte gezeigt werden, dass der P2Y12-Rezeptor sowohl in ausdifferenzierten murinen als auch in humanen braunen und weißen Adipozyten exprimiert wird. Die Expression ließ sich sowohl durch Ernährung als ... -
Search for a heavy charged Higgs boson decaying into a W boson and a 125 GeV Higgs boson, in final states with leptons and jets, with the ATLAS experiment at the LHC
(2025-07-04)This thesis presents a first search for a heavy charged Higgs boson produced in association with a top- and a bottom-quark, and decaying into a <em>W</em> boson and a 125 GeV Higgs boson decaying subsequently into a pair ... -
Perennial biomass crops as sustainable feedstock for carbon dioxide fixation in building materials
(2025-07-04)The aim of a bio-based and circular economy is to help reduce dependence on fossil resources and greenhouse gas emissions. Perennial biomass crops (PBC) can offer advantages such as low fertilizer requirements which can ... -
Measurement of the tZq differential cross-section with the ATLAS detector at the LHC
(2025-07-04)The production of a top quark in association with a Z boson is studied using proton-proton collision data collected by the ATLAS detector at the LHC during 2015 to 2018 at a centre of mass energy of 13 TeV. The differential ... -
The Impact of the Mesoprefrontal System on the Development of Murine Prefrontal Cortex
(2025-07-04)The prefrontal cortex (PFC) is involved in important cognitive processes and undergoes a lengthy functional and anatomical maturation process during postnatal development, which in mammals lasts until early adulthood. ... -
Risikomanagement mittels hochauflösender Vorderabschnittsbildgebung bei Glaukom-Drainage-Implantaten
(2025-07-04)Die Glaukomerkrankung ist eine häufige und bedeutsame ophthalmologische Erkrankung, dessen Bedeutung als Erblindungsursache weltweit ausgesprochen groß ist und in Zukunft, aufgrund demographischer Entwicklungen, noch weiter ... -
The Evolution of Pholcidae (Araneae) Spiders
(2025-07-03)(noch nicht zugänglich / not yet accessible) -
Smart Farming Technology and the Environmental and Social Efficiency of European Agriculture
(2025-06-27)The agricultural sector faces growing pressure to meet the increasing demand for food while mitigating environmental damage and being fair to farmers and rural populations. Current policy debates in the EU emphasise steering ... -
Development of photoreceptor-aptamer systems for the spatiotemporal control of gene expression
(2025-06-27)Gene expression regulation is a fundamental process underlying numerous biological mechanisms, from development and homeostasis to cellular responses and disease progression. Advances in the ability to control gene expression ... -
Vergleichende Analyse des Überlebens von Patienten mit infra- versus supratentoriell lokalisiertem neu-diagnostiziertem Glioblastom
(2025-06-27)Hintergrund: Glioblastome zählen zu den aggressivsten primären Hirntumoren bei Erwachsenen. Während die meisten Glioblastome supratentoriell lokalisiert sind, treten zerebelläre Glioblastome äußerst selten auf und machen ... -
Multimodal assessment of adult attention-deficit hyperactivity disorder using virtual reality
(2025-06-27)Attention-deficit hyperactivity disorder (ADHD) is a complex and heterogeneous disorder. As a result of this heterogeneity, it has been difficult to identify reliable objective tests and markers for ADHD. The neuropsychological ... -
Advances in Machine Learning Approaches for Biostatistical Learning
(2025-06-27)This habilitation thesis summarized current state-of-art advances in machine learning for biomedical applications. The first contribution was the development of a framework for tuning KDSN to increase prediction performance ... -
Large Scale Single Cell RNA sequencing Analysis of Lung Tissue and Bronchoalveolar Lavage Fluid from Patients with Chronic Obstructive Pulmonary Disease, COVID-19 and Idiopathic Pulmonary Fibrosis
(2025-06-26)Idiopathic Pulmonary Fibrosis (IPF) is a progressive interstitial lung disease of unknown etiology, primarily characterized by the development of fibrosis. IPF affects 3–9 out of every 100,000 people globally, with its ... -
Diskrepanzen zwischen Internationalisierung und Internalisierung an deutschen Hochschulen: Implizite Hürden ausländischer Studienbewerber*innen am Beispiel des Studienkollegs der Fachhochschule des Mittelstands in NRW
(2025-06-06)Ein Studienkolleg ist in seiner Funktion als Übergangsbrücke im Hochschulzugangsbereich für ausländische Studienbewerber*innen verortet und dient vornehmlich der Gewinnung von internationalen Student*innen. Diese Kollegiat*innen ... -
Rewiring the Brain: Insights into Electroconvulsive and Magnetic Stimulation Therapies and Their Impact on Cognition and Neural Processing
(2025-06-25)Depressive disorders are a group of debilitating and at times life-threatening diseases affecting millions of individuals worldwide. They interfere with most aspects of everyday life, such as social behavior, affective ... -
Safe-DS: A Toolkit for Safe Development of Data Science Pipelines
(2025-06-25)This work introduces the Safe-DS stack for developing data science (DS) pipelines: <br/> The Safe-DS Python library offers commonly needed DS operations behind a simple, integrated, and consistent API. It is implemented ... -
Characterization of dopaminergic innervation and receptor expression in mouse models and patients with Focal Cortical Dysplasia
(2025-06-25)Focal Cortical Dysplasia (FCD) type 2 is the most prevalent malformation of cortical development (MCD) associated with pharmacoresistant focal epilepsy, frequently located in the frontal cortex. Neuropathological features ... -
Altered interaction of physiological activity and behavior affects risky decision-making in ADHD
(2023-04-20)<b>Background:</b> Adult attention-deficit/hyperactivity disorder (ADHD) is often associated with risky decision-making behavior. However, current research studies are often limited by the ability to adequately reflect ... -
Influence of Cementation Mode and Ferrule Design on the Fatigue Resistance of Monolithic Zirconia Endocrowns
(2024-02-19)<strong>Background:</strong> Classic endocrowns made of dental ceramics are considered a promising alternative to traditional post-endodontic restorations. The use of circular ferrules in endocrowns is a topic of controversial ...
