Fakultäten der Universität Bonn: Fakultäten der Universität Bonn: Neuzugänge
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Key factors for sustainable working conditions in emergency departments: An EUSEM-initiated, Europe-wide consensus survey
(2025-02)<em>Background and importance</em> Modern emergency medicine (EM) is a complex, demanding, and occasionally stressful field of work. Working conditions, provider well-being, and associated health and performance outcomes ... -
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function
(2024-04-29)Promoting brown adipose tissue (BAT) activity innovatively targetsobesity and metabolic disease. While thermogenic activation of BAT is wellunderstood, the rheostatic regulation of BAT to avoid excessive energy dissipation ... -
Exploring the role of tryptophan in biennial bearing: A mobile molecule that is exported from growing apples but does not suppress flowering
(2024-12-23)<em>Background of the study</em> – <strong>Apple (<em>Malus × domestica</em> Borkh.) production faces significant challenges, with biennial (or alternate) bearing being a major obstacle to stable yields. Natural high crop ... -
The Spectrum of Functional, Structural and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report
(2025-02-03)<em><strong>Introduction:</strong></em> There is an unmet medical need for therapies in intermediate age-related macular degeneration (iAMD). The prospective European multi-center cohort study MACUSTAR validates structural, ... -
Bytes the Dust: Normative Notions in Decommissioning Digital Doppelgängers
(2025-01-29)In recent debates on digital twins, much attention has been paid to understanding the interaction between individuals and their digital representations (Braun, 2021). Iglesias et al. (2025) shed new light on this debate, ... -
The hard work of future-making: Alienated futures, invisible labour and liberation
(2025-01-02)This article proposes that future-making is hard work. Drawing on examples of work on and around infrastructure projects in East Africa, we show how people orient themselves towards the future through both imagination and ... -
Deep Learning–Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy
(2025-01-02)<strong>PURPOSE.</strong> To quantify outer retina structural changes and define novel biomarkers of inherited retinal degeneration associated with biallelic mutations in <em>RPE65 (RPE65</em>-IRD) in patients before and ... -
TFAP2E is implicated in central nervous system, orofacial and maxillofacial anomalies
(2024-12-23)<strong>Background</strong> Previous studies in mouse, <em>Xenopus</em> and zebrafish embryos show strong <em>tfap2e</em> expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in ... -
Ergebnisse von abdomino-thorakalen Eingriffen am Lymphgefäßsystem zur Behandlung traumatischer und nicht-traumatischer Lymphleckagen
(2025-08-11)<strong>Hintergrund:</strong><br /> Chylöse Ergüsse wie Chylothorax oder Chylaszites stellen seltene, aber schwerwiegende Krankheitsbilder dar, die häufig mit hoher Morbidität und Mortalität einhergehen. Ziel dieser Studie ... -
Across Diagnostic Boundaries: Genetic Variants for Neuropsychiatric Disorders and their Association with Human Brain Structure
(2025-08-11)With the advances in genome-wide association studies (GWAS), hundreds of genetic variants have been identified for neuropsychiatric disorders. Strikingly, many of these genetic variants showed complex associations across ... -
NIS-Seq enables cell-type-agnostic optical perturbation screening
(2024-12-19)Optical pooled screening offers a broader-scale alternative to enrichment-based perturbation screening, using fluorescence microscopy to correlate phenotypes and perturbations across single cells. Previous methods work ... -
Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei
(2024-12-10)<strong>Background:</strong> <em>Mansonella perstans</em> is transmitted by <em>Culicoides</em> species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis ... -
Digital platforms in the agricultural sector: Dynamics of oligopolistic platformisation
(2024-12-26)This paper introduces the concept of 'oligopolistic platformisation' to capture the specific dynamics of collaboration and competition between multinational upstream agribusinesses and Big Tech companies in the agricultural ... -
Comparative Analysis of Shear Bond Strength in Orthodontic Brackets Between Milled and 3D-Printed Definitive CAD/CAM Restorations
(2024-10-18)<strong>Objective:</strong> The objective of this study was to evaluate the effect of different surface treatment methods on the shear bond strength (SBS) of metal brackets bonded to two types of CAD/CAM composite restorations: ... -
Schistosomiasis–Microbiota Interactions: A Systematic Review and Meta-Analysis
(2024-10-16)Introduction: Schistosomiasis, a tropical disease affecting humans and animals, affected 251.4 million people in 2021. <em>Schistosoma mansoni, S. haematobium, S. intercalatum</em>, and <em>S. japonicum</em> are primary ... -
Entwicklung und Validierung eines Screeninginstrumentes zur Diagnose einer Sepsis nach Schlaganfall
(2025-08-08)Schlaganfall-assoziierte Infektionen können eine Sepsis hervorrufen, die mit einem schlechten klinischen Outcome assoziiert ist. Die lebensbedrohliche Organdysfunktion, welche die Sepsis definiert, kann mittels Sequential ... -
The ethnoarchaeology of pottery tempers in the bolivian Amazon: Two indigenous traditions of paste recipes with preparations of freshwater sponge, pottery sherds, bone, and turtle shell
(2024-10-14)This article integrates ethnoarchaeological investigations of the pottery <em>chaîne opératoire</em> from two research projects conducted with Indigenous peoples of the Llanos de Moxos region in the Bolivian Amazon. Two ... -
Single-neuron representations of odours in the human brain
(2024-10-09)Olfaction is a fundamental sensory modality that guides animal and human behaviour. However, the underlying neural processes of human olfaction are still poorly understood at the fundamental—that is, the single-neuron—level. ... -
The multiple dimensions of resilience in agricultural trade networks
(2024-09-24)The global food and agricultural trade network is crucial for food security. Shocks such as those posed by extreme weather events, conflicts, pandemics, and economic crises can test the resilience of the trade network to ...
