The Faculty of Medicine: Browsing Medizinische Fakultät by Resource Type "doc-type:article"
Now showing items 1-20 of 37
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Additive prognostic impact of the cerebrospinal fluid arginine/ornithine ratio to established clinical scores in aneurysmal subarachnoid hemorrhage
Weller, Johannes; Lampmann, Tim; Asoglu, Harun; Schneider, Matthias; Ehrentraut, Stefan Felix; Lehmann, Felix; Güresir, Erdem; Dorn, Franziska; Petzold, Gabor; Vatter, Hartmut; Zimmermann, Julian (2023-04-14)Cerebrospinal fluid (CSF) metabolites are increasingly recognized as prognostic factors in aneurysmal subarachnoid hemorrhage (SAH). The CSF arginine/ ornithine ratio (Arg/Orn) was shown to predict cerebral vasospasms ... -
Assessing the quality of life of patients with metastatic castration-resistant prostate cancer with bone metastases receiving [223Ra]RaCl2 therapy
Sraieb, Miriam; Hirmas, Nader; Conrad, Rupert; Marinova, Milka; Essler, Markus; Herrmann, Ken; Ahmadzadehfar, Hojjat (2020-08-19)[223Ra]RaCl2 dichloride treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) is associated with improved overall survival (OS) and a delay in the time to the first ... -
Cost-effectiveness and Quality of Specialized and Routine Care in a German Cohort of Patients with Chronic Pruritus
Müller, Svenja; Ständer, Sonja; Naatz, Mandy; Augustin, Matthias; Steinke, Sabine (2023-04-21)Chronic pruritus is a prevalent interdisciplinary symptom with a strong influence on health-related quality of life. Patients need extensive diagnostics and long-term treatment. This retrospective and prospective cohort ... -
Cytokine Production of CD56bright Natural Killer Cells From Human Immunodeficiency Virus–Infected Individuals Under Effective Antiretroviral Therapy
ToVinh, Michael; Hörr, Gregor; Dobrikova, Kristiyana; Gotter, Christina; Rommel, Clemens; Hoffmeister, Christoph; Raabe, Jan; Kaiser, Kim M.; Finnemann, Claudia; Bischoff, Jenny; Rieke, Gereon J.; Wilhelm, Christoph; Schmitt, Vanessa; Möhl, Christoph; Aghabeig, Mansoureh; Schwarze-Zander, Carolynne; Boesecke, Christoph; van Bremen, Kathrin; Wasmuth, Jan-Christian; Strassburg, Christian P.; Rockstroh, Jürgen K.; Spengler, Ulrich; Krämer, Benjamin; Nattermann, Jacob (2022-09-01)Human immunodeficiency virus (HIV) infection is associated with impaired natural killer (NK) cell activity, which is only incompletely restored under antiretroviral therapy. Analyzing the bioenergetics profiles of oxygen ... -
The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes
Schult, Philipp; Paeschke, Katrin (2020-10-12)DHX36 is a member of the DExD/H box helicasefamily, which comprises a large number of proteinsinvolved in various cellular functions. Recently, thefunction of DHX36 in the regulation of G-quadruplexes(G4s) was ... -
Delphi study for the development and preliminary validation of an item set for the assessment of non-experts’ AI literacy
Laupichler, Matthias Carl; Aster, Alexandra; Raupach, Tobias (2023-01-12)Artificial intelligence literacy is a concept that has been the focus of exhaustive research recently. However, there are very few psychometrically sound and thoroughly evaluated instruments that attempt to assess AI ... -
Effects of Different Titanium Surface Treatments on Adhesion, Proliferation and Differentiation of Bone Cells: An In Vitro Study
Stoilov, Milan; Stoilov, Lea; Enkling, Norbert; Stark, Helmut; Winter, Jochen; Marder, Michael; Kraus, Dominik (2022-09-05)The objective of this study was to evaluate the impacts of different sandblasting procedures in acid etching of Ti6Al4V surfaces on osteoblast cell behavior, regarding various physicochemical and topographical parameters. ... -
Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors
Klausen, Christina; Kaiser, Fabian; Stüven, Birthe; Hansen, Jan N.; Wachten, Dagmar (2019-11-14)The second messenger 3´, 5´-cyclic nucleoside adenosine monophosphate (cAMP) plays a key role in signal transduction across prokaryotes and eukaryotes. Cyclic AMP signaling is compartmentalized into microdomains to fulfil ... -
Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development
Vieira, José Ricardo; Shah, Bhavin; Dupraz, Sebastian; Paredes, Isidora; Himmels, Patricia; Schermann, Géza; Adler, Heike; Motta, Alessia; Gärtner, Lea; Navarro-Aragall, Ariadna; Ioannou, Elena; Dyukova, Elena; Bonnavion, Remy; Fischer, Andreas; Bonanomi, Dario; Bradke, Frank; Ruhrberg, Christiana; Ruiz de Almodóvar, Carmen (2022-12-21)How the vascular and neural compartment cooperate to achieve such a complex and highly specialized structure as the central nervous system is still unclear. Here, we reveal a crosstalk between motor neurons (MNs) and ... -
Enemy or ally? Fasting as an essential regulator of immune responses
Wilhelm, Christoph; Surendar, Jayagopi; Karagiannis, Fotios (2021-04-14)Nutrition is essential for supplying an organism with sufficient energy to maintain its bodily functions. Apart from serving as an energy supply, the immunomodulatory effects of diet are emerging as a central aspect of ... -
Evaluations of the Authenticity of News Media Articles and Variables of Xenophobia in a German Sample: Measuring Out-Group Stereotypes Indirectly
Plieger, Thomas; Al-Haj Mustafa, Sarah; Schwandt, Sebastian; Heer, Jana; Weichert, Alina; Reuter, Martin (2023-03-11)Xenophobic and right-wing attitudes have become a major issue in Western societies. The present study investigated how such attitudes and stereotypes influence media perception in terms of identifying manipulated news ... -
Experimental Induction of Micro- and Macrosomatognosia: A Virtual Hand Illusion Study
Anders, David; Berisha, Arbnor; Selaskowski, Benjamin; Asché, Laura; Thorne, Jeremy D.; Philipsen, Alexandra; Braun, Niclas (2021-04-29)Although body size misperceptions are known to occur under various neurological and psychiatric conditions, their neurocognitive underpinnings are not yet resolved. Accordingly, it would be beneficial to have an experimental ... -
Experimental Induction of Micro- and Macrosomatognosia: A Virtual Hand Illusion Study
Anders, David; Berisha, Arbnor; Selaskowski, Benjamin; Asché, Laura; Thorne, Jeremy D.; Philipsen, Alexandra; Braun, Niclas (2021-04-29)Although body size misperceptions are known to occur under various neurological and psychiatric conditions, their neurocognitive underpinnings are not yet resolved. Accordingly, it would be beneficial to have an experimental ... -
Exploring the Applicability of General Dietary Recommendations for People Affected by Obesity
Marsall, Matthias; Engelmann, Gerrit; Teufel, Martin; Bäuerle, Alexander (2023-03-25)(1) Obesity has emerged as a major public health challenge with increasing prevalence globally. The General Dietary Behavior Inventory (GDBI) was developed based on official dietary recommendations. However, little is known ... -
Extracellular vesicles derived from Hepatitis-D Virus infected cells induce a proinflammatory cytokine response in human peripheral blood mononuclear cells and macrophages
Jung, Stephanie; Altstetter, Sebastian Maximilian; Wilsch, Florian; Shein, Mikhail; Schütz, Anne Kathrin; Protzer, Ulrike (2020-02-14)Hepatitis D Virus (HDV) is a satellite virus requiring a Hepatitis B Virus (HBV) envelope proteins for productive infection. Hepatitis D is the most severe form of viral hepatitis and is a global health threat affecting ... -
Health and Asylum Seekers in Europe
Tourneur, Isabel; Walker, Xaviour; Wiley, Elizabeth; Mattar, Caline; Esen, Fehim; Mijaljica, Goran; Roditis, Kostas; Louis, Kostas; Murt, Ahmet; Hornung, Thorsten (2015-10) -
How to control cyclic nucleotide signaling by light
Jansen, Vera; Jikeli, Jan F.; Wachten, Dagmar (2017-03-10)Optogenetics allows to non-invasively manipulate cellular functions with spatio-temporal precision by combining genetic engineering with the control of protein function by light. Since the discovery of channelrhodopsin has ... -
Innate lymphoid cells - key immune integrators of overall body homeostasis: ILC – key immune integrators of overall body homeostasis
Karagiannis, Fotios; Wilhelm, Christoph (2018-06-04)The maintenance of the tissue barrier is essential to protect the host from external pathogens, thus ensuring the survival of the organism. This process requires the integration of various physiological signals originating ... -
Intervertebral Disc and Adipokine Leptin—Loves Me, Loves Me Not
Curic, Goran (2020-12-31)Leptin—the most famous adipose tissue-secreted hormone—in the human body is mostly observed in a negative connotation, as the hormone level increases with the accumulation of body fat. Nowadays, fatness is becoming another ... -
Job Satisfaction and Chronic Stress of General Practitioners and Their Teams: Baseline Data of a Cluster-Randomised Trial (IMPROVEjob)
Degen, Lukas; Linden, Karen; Seifried-Dübon, Tanja; Werners, Brigitte; Grot, Matthias; Rind, Esther; Pieper, Claudia; Eilerts, Anna-Lisa; Schroeder, Verena; Kasten, Stefanie; Schmidt, Manuela; Goebel, Julian; Rieger, Monika A.; Weltermann, Birgitta M.; On Behalf Of The IMPROVEjob Consortium (2021-09-08)Background: A high prevalence of poor job satisfaction and high chronic stress is documented for general practitioners (GPs) and non-physician practice staff from various countries. The reasons are multifactorial ...