bonndoc - Der Publikationsserver der Universität Bonn: Recent submissions
Now showing items 81-100 of 11855
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Beneficial effects of non-invasive physical plasma on human periodontal ligament cells in vitro
(2024-11-19)<strong>Introduction:</strong> Periodontitis is a chronic inflammatory disease of the periodontium that can lead to the loss of affected teeth if left untreated. It is induced by a multifactorial process centered on microbial ... -
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation
(2024-04-26)The lung is constantly exposed to the outside world and optimal adaptation of immune responses is crucial for efficient pathogen clearance. However, mechanisms that lead to lung-associated macrophages' functional and ... -
First-Line Treatment for Advanced Hepatocellular Carcinoma: A Three-Armed Real-World Comparison
(2024-01-13)<strong>Background and Aim:</strong> There are several existing systemic 1st- line therapies for advanced hepatocellular carcinoma (HCC), including atezolizumab/bevacizumab (Atez/Bev), sorafenib and lenvatinib. This study ... -
Aberrant hippocampal Ca2+ microwaves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators
(2024-07-23)Genetically encoded calcium indicators (GECIs) such as GCaMP are invaluable tools in neuroscience to monitor neuronal activity using optical imaging. The viral transduction of GECIs is commonly used to target expression ... -
Use of the FallAkte Plus System as an IT Infrastructure for the North Rhine-Westphalian General Practice Research Network: Mixed Methods Usability Study
(2024-05-20)<strong>Background:</strong> Primary care research networks can generate important information in the setting where most patients are seen and treated. However, this requires a suitable IT infrastructure (ITI), which the ... -
Assessing Electronic Health Literacy in Individuals With the Post–COVID-19 Condition Using the German Revised eHealth Literacy Scale: Validation Study
(2024-04-25)<strong>Background:</strong> The eHealth Literacy Scale (eHEALS) is a widely used instrument for measuring eHealth literacy (eHL). However, little is known so far about whether the instrument is valid for the assessment ... -
Circular genomes of two bacterial strains capable of growing in a CO2-containing atmosphere
(2023-11-29)The bacterial strains <em>Brochothrix thermosphacta</em> DH-B18 and <em>Rathayibacter sp.</em> DH-RSZ4 were isolated from raw sausage and escalope samples and grown in a CO<sub>2</sub>-rich modified atmosphere. Here, we ... -
Prospective effects of an artificial intelligence-based computer-aided detection system for prostate imaging on routine workflow and radiologists' outcomes
(2023-12-06)<em>Objectives:</em> Artificial intelligence (AI) is expected to alleviate the negative consequences of rising case numbers for radiologists. Currently, systematic evaluations of the impact of AI solutions in real-world ... -
IL-6–Dependent STAT3 Activation and Induction of Proinflammatory Cytokines in Primary Sclerosing Cholangitis
(2023-06-01)<strong>INTRODUCTION: </strong>Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease with periductal inflammation and fibrosis. Genetic studies suggest inflammatory cytokines and IL-6–dependent activation ... -
Impaired immunogenicity after vaccination for SARS-CoV-2 in patients with gastrointestinal cancer: does tumor entity matter?
(2023-06-26)<strong>Background:</strong> SARS-CoV-2 immunogenicity in patients with gastrointestinal cancer (GI cancer) following second and third vaccination was analyzed.<br /> <strong>Methods:</strong> A total of 125 patients under ... -
Development of the "Scale for the assessment of non-experts' AI literacy": an exploratory factor analysis
(2023-09-27)Artificial Intelligence competencies will become increasingly important in the near future. Therefore, it is essential that the AI literacy of individuals can be assessed in a valid and reliable way. This study presents ... -
Sustainability trade-offs in animal husbandry: Consumers' choice when they can't have it all
(2023-10-06)This paper investigates consumer choices in the presence of conflicting goals, with and without information making conflicts salient. An experimental online study was conducted with a sample of German consumers, focusing ... -
Structure-affinity and structure-residence time relationships of macrocyclic Gαq protein inhibitors
(2023-04-21)The macrocyclic depsipeptides YM-254890 (YM) and FR900359 (FR) are potent inhibitors of Gα<sub>q/11</sub> proteins. They are important pharmacological tools and have potential as therapeutic drugs. The hydrogenated, ... -
Behaviour intention to eat reared crickets in Myanmar: the effects of trust, knowledge, and perceived quality
(2023-09-26)Edible insects are a good source of proteins, fats, and micronutrients for human consumption. Crickets are one of the most widely reared insects worldwide. They require less capital spending and less space and water ... -
The Investigations on Diterpene Biosynthesis through Substrate and Protein Engineering
(2025-10-20)This cumulative doctoral dissertation "The Investigations on Diterpene Biosynthesis through Substrate and Protein Engineering" concentrates on diterpene biosynthesis from various aspects, including non-natural biotransformation, ... -
The Effects of Differential Constraints and Surface Energies on Scaling Laws for Singular Perturbation Problems
(2025-10-20)Motivated by mathematical models for phase transformations, arising, for example, in shape-memory alloys, and for micromagnetism in ferromagnetic materials, we study a class of A-free differential inclusions quantitatively. ... -
Low-Valent Heavier Tetrel Compounds Supported by N-heterocyclic Carbenes: A Comprehensive Experimental and Theoretical Perusal
(2025-10-17)(noch nicht zugänglich / not yet accessible) -
Generic Malware Unpacking: Existing Solutions, Requirements, New Approach for Windows Malware
(2025-10-17)Malware continues to be a substantial threat to cybersecurity, amplified by the widespread use of malicious executable packing, so-called packers. These packers inflate the number of unique samples in the wild by introducing ... -
Dimensional Crossover in a Photonic Quantum Gas
(2025-10-17)For many-body quantum systems, dimensionality is known to exert a profound influence on the physical behaviour, allowing for the shaping of distinct phases of matter. In general, for lower dimensions, enhanced fluctuations ...
