E-Dissertationen: Search
Now showing items 1-10 of 220
Chemical modulation of guanine nucleotide exchange factor activity: A small molecule inhibitor for the Rabex-5 mediated Rab5 activation
(2013-09-02)
The small GTPase Rab5 is a key regulator in the early endocytic pathway. The activity of Rab5 is controlled by numerous guanine nucleotide exchange factors (GEFs), which catalyse the exchange of GDP for GTP. However, the ...
Bestimmung der Doppelpolarisationsobservablen E für die Reaktion γp → pπ0 am CBELSA/TAPS-Experiment
(2013-05-07)
Zur Untersuchung der starken Wechselwirkung im störungstheoretisch nicht behandelbaren Bereich und für ein besseres Verständnis des Inneren Aufbaus der Nukleonen ist die Baryonenspektroskopie ein wichtiges Werkzeug. Im ...
On Approximability of Bounded Degree Instances of Selected Optimization Problems
(2013-08-07)
In order to cope with the approximation hardness of an underlying optimization problem, it is advantageous to consider specific families of instances with properties that can be exploited to obtain efficient approximation ...
BPS state counting using wall-crossing, holomorphic anomalies and modularity
(2013-07-25)
In this thesis we examine the counting of BPS states using wall-crossing, holomorphic anomalies and modularity. We count BPS states that arise in two setups: multiple M5-branes wrapping P x T2, where P denotes ...
Untersuchungen zur Polyoloxidation in Gluconobacter oxydans und Thermotoga maritima
(2013-08-05)
Die Biotechnologie nutzt für industrielle Produktionsverfahren Organismen, Enzyme oder Enzymsysteme. Einige Enzyme des mesophilen Essigsäurebakteriums Gluconobacter oxydans und des thermophilen Eubakteriums Thermotoga ...
Molekulare und zellbiologische Mechanismen der Kreuzpräsentation
(2013-09-02)
Die Kreuzpräsentation von Antigen in der Milz ist eine essentielle Voraussetzung für die Induktion von zytotoxischen T-Zellantworten gegen Viren oder Tumore. Aus welchem Grund nur einzelne APC-Subtypen zur Kreuzpräsentation ......
Recent and future climate conditions and their impact on viticulture at the Upper Moselle region
(2013-08-06)
Climate plays a decisive role in viticulture. It has a large impact on the duration of the vegetative cycle, on the health of the vines and on the quality of the harvest. Under a changing climate wine characteristics may ...
Centralisers of polynomially growing automorphisms of free groups
(2013-07-31)
The main theorem of this thesis asserts that many centralisers in the automorphism groups Aut(F_n) and Out(F_n) of the free group F_n satisfy finiteness property VF, i.e. these centralisers have a finite index subgroup ...
Investigation of the endocannabinoid system using in vivo and in vitro models
(2013-07-31)
The endocannabinoid system (ECS) is a retrograde signaling system that plays an important, pro-homeostatic role in the central nervous system (CNS) by adjusting synaptic communication. The system comprises a set of presynaptic ...
Tracking and vertex reconstruction with the PANDA Micro-Vertex-Detector
(2013-07-31)
PANDA is one of the experiments which will be installed at the FAIR facility in Darmstadt. It will study the collisions of an antiproton beam with different fixed targets.