E-Dissertationen: Search
Now showing items 3421-3430 of 4071
Intrinsic Dimension Estimation using Simplex Volumes
(2018-01-18)
In this thesis, we introduce a novel approach for the estimation of the intrinsic dimension of high-dimensional datasets. For this purpose, the volumes of high-dimensional simplices, with vertex points sampled from local ...
X-Ray Studies of Galaxy Clusters and Groups: Gas Properties in the Exceptional Cases of Faint Outskirts, High Redshift and a Merging Event
(2018-01-26)
The history and evolution of the universe, the understanding of the formation of structures and the investigation of a wealth of astrophysical phenomena are the topical subjects in present-day galaxy cluster physics and ......
Flooding in Dhaka, Bangladesh, and the challenge of climate change
(2018-02-16)
The country of Bangladesh is located in the Ganges-Brahmaputra-Meghna river delta, and faces multiple natural hazards, in particular flooding, and other challenges such as sea-level rise and a growing population. Dhaka, ...
Hodge theoretic aspects of Soergel bimodules and representation theory
(2018-01-19)
In the last years, methods coming from Hodge theory have proven to be fruitful in representation theory, most remarkably leading to a new algebraic proof of the Kazhdan-Lusztig conjectures based on the Hodge theory of ...
Functional cooperation of Toll-like receptor signaling and the high-affinity receptor for IgE, FcεRI, on human Langerhans cells
(2018-01-15)
Atopic dermatitis (AD) is a multifactorial severe skin disease with increasing incidence in western countries. In the disease, Langerhans cells (LC) play a pivotal role in bridging innate and adaptive immunity through ......
2-D Anisotropic Inversion of Frequency-Domain Induced Polarization Data
(2018-03-23)
Measured data in IP (time or frequency domain) are usually interpreted with inversion algorithms, which may be based on stochastic or iterative schemes for finding an optimal data-associated model of the subsurface. Despite ...
The endophytic fungus Stemphylium globuliferum – secondary metabolites and biological activities
(2018-01-22)
Fungi are a tremendous source of pharmaceutically significant compounds, e.g. the life saving immunosuppressant drug mycophenolic acid. The current project focused on the investigation of the mold fungus Stemphylium ......
Cisplatin resistance is associated with altered signalling in NSCLC cells
(2018-01-18)
The efficacy of cisplatin-based chemotherapy in cancer is limited by the occurrence of innate and acquired drug resistance. In order to better understand the mechanisms underlying acquired cisplatin resistance, the ...
Optimierung der mikrobiellen Produktion von präbiotischen Zuckerderivaten auf Levan-Basis
(2021-04-21)
Die vorliegende Arbeit befasste sich mit der Entwicklung und Optimierung einer mikrobiellen Produktionsstrategie zur Synthese ß-2,6-glykosidisch verknüpfter Fruktane. Levan (ß-2,6-glykosidisch verknüpftes Fruktan) und ......
Untersuchungen zur heterologen Biosynthese des seltenen kompatiblen Soluts Nε-Acetyl-β-Lysin
(2020-08-28)
Das Aminosäurederivat Nε-Acetyl-β-Lysin (NAβL) wird von methanogenen Archaeen und einigen Vertretern der Bakterien zur Anpassung an osmotischen Stress produziert. Bisher wurden vor allem die zur Produktion ......
Studies on the heterologous biosynthesis of the rare compatible solute Nε-acetyl-β-lysine
The amino acid derivative Nε-acetyl-β-lysine (NAβL) is produced by methanogenic ......
Studies on the heterologous biosynthesis of the rare compatible solute Nε-acetyl-β-lysine
The amino acid derivative Nε-acetyl-β-lysine (NAβL) is produced by methanogenic ......