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Modelling the hydrological impact of rice intensification in inland valleys in Benin (West Africa)
(2018-01-25)
The aim of this study is to assess the impact of climate change and rice intensification on water availability, water quality, and rice production. A spatial explicit approach was developed to determine suitable areas for ...
The impact of dendritic calcium control on interneurons function within the hippocampal circuit
(2018-05-11)
In the past few decades, dendritic integration has been extensively studied in hippocampal excitatory cells (for review see Stuart and Spruston 2015). However, much less effort has been put into understanding inhibitory ...
Predicting Rules for Cancer Subtype Classification using Grammar-Based Genetic Programming on various Genomic Data Types
(2018-03-12)
With the advent of high-throughput methods more genomic data then ever has been generated during the past decade. As these technologies remain cost intensive and not worthwhile for every research group, databases, such as ...
BonnMag a Computer Program for Angular Overlap Modeling of all fn-Systems: New Insights into Ligand-field splitting of Lanthanide and Actinide ions
(2018-02-16)
In this thesis the development of the computer program BonnMag is described. By using BonnMag the excited state energies, magnetic susceptibilities and moments can be calculated for all fn systems (1 ≤ n ≤ 13) ...
The L2-Torsion Polytope of Groups and the Integral Polytope Group
(2018-01-24)
This thesis contains three projects revolving around the L2-torsion polytope. First we show that the L2-torsion polytope of infinite elementary amenable groups vanishes. Then we establish a link between ...
A New Continuous 4π-Frozen-Spin-Target for the Crystal Barrel Experiment
(2018-01-29)
The CBELSA/TAPS experiment has produced a large amount of data on photo-production reactions in double polarization reactions. For this a frozen-spin target has been used, which consists of a horizontal dilution refrigerator ......
Xenosialitis modulates the function of the Alzheimer’s disease associated SIGLEC3 in human THP1 macrophages
(2018-03-26)
Chronic inflammation is an undisputed feature of late onset Alzheimer’s disease (LOAD). Activated microglia,found around amyloid beta (Aβ) plaques are implicated as the source of inflammation. However they are incapable ...
Application of population, physiologically based, and semi-physiological pharmacokinetic modeling to assess sources of pharmacokinetic variability in individual drugs
(2020-06-05)
Large inter- and intra-individual variability in the response of drugs causes difficulties for clinicians to choose appropriate dosing regimens to target their therapeutic range. While underexposure might cause sub-therapeutic ...
Théorie de Bruhat-Tits, grassmanniennes affines et modèles locaux
(2020-10-02)
Nous développons la théorie de Bruhat-Tits pour les groupes quasi-réductifs sur les corps discrètement valués, henséliens et excellents, qui se quasi-déploient sur l'henselisé strict. Ensuite, cette théorie est appliquée ...
Generation of an RNA sensor to probe glycolysis in living cells via the key metabolite fructose 1,6-bisphosphate
(2021-06-24)
Glycolysis is the cornerstone of cell metabolism and is one of the oldest biochemical pathways known to life. Yet, methods to study glycolysis in single living cells are lacking. The glycolytic intermediate Fructose ...