E-Dissertationen: Search
Now showing items 891-900 of 1148
Characterization of Ceramide synthase 2 dysfunctions caused by targeted mutations in transgenic mice
(2020-02-10)
Ceramide species are the precursor of sphingolipids, which serve as structural components of biological membranes or are bioactive molecules. In mammals, ceramides are synthesised by a family of ceramide synthases (CerS) ......
The role of MyD88-dependent signaling pathways in skin mast cells in UVB-induced skin diseases
(2022-03-04)
Excessive UV irradiation is a major risk factor for health. While chronic long-term UV exposure induces skin aging and suppression of the immune system, acute UV exposure leads to skin inflammation, also known as sunburn. ...
The enzyme HPGD is critical for regulatory T cell function in adipose tissue
(2020-02-06)
Regulatory T cells (Treg cells) are essential for maintaining immune homeostasis. However, how Treg cells exert their function in tissue specific environments is often unknown. We have found ......
Contributions towards a better understanding of millipede phylogenetics and sawfly genomics
(2021-03-11)
A loss of biodiversity on a scale and rate comparable to the great extinction events, as a result of anthropogenic activity, has been documented for plants, animals, and micro-organisms. In order to foster a sustainable ...
Analyse der Thermostabilität mitochondrialer Proteine anhand der Protein-Disaggregation durch Hsp78 in Bäckerhefe
(2021-02-11)
Alle Organismen zeichnen sich durch spezifische auf ihre Lebensbedingungen angepasste Charakteristika aus. Hefen, darunter auch die Bäckerhefe Saccharomyces cerevisiae, besitzt eine Vielzahl an spezialisierten Proteinen, ...
Neuronal and Circuit Architecture Underlying Feeding Behavior in Drosophila
(2021-06-28)
Feeding is elemental for survival and one of the most common activities of animals. Little is known about the organization of neuronal circuits controlling feeding behavior in the cen-tral nervous system. This study maps, ...
Evaluation of protective immune responses against Litomosoides sigmodontis and analysis of L. sigmodontis extract on T cell modulation and glucose tolerance in diet-induced obese mice
(2019-11-11)
Parasitic helminths are responsible for numerous tropical diseases which represent a major health problem in tropical and subtropical regions such as lymphatic filariasis (elephantiasis), causing lymphedema in limbs and ......
Parasitäre Helminthen sind für eine Vielzahl von tropischen Krankheiten verantwortlich, die ein großes Gesundheitsproblem in den Tropen und Subtropen darstellen. Bei der lymphatischen Filariose (Elephantiasis) leiden ......
Parasitäre Helminthen sind für eine Vielzahl von tropischen Krankheiten verantwortlich, die ein großes Gesundheitsproblem in den Tropen und Subtropen darstellen. Bei der lymphatischen Filariose (Elephantiasis) leiden ......
Actin Regulatory Proteins in Dendritic Arborisation Neurons of Drosophila
(2019-10-23)
Dendrites are highly branched extensions of nerve cells, along which signals are received and propagated to the cell body. The correct morphology of dendrites is essential for the function of the nervous system. The ...
Establishment of anti-apoptotic brakes in human neurons during maturation
(2019-11-29)
Neurons represent a highly specialised cell population of the central and peripheral nervous system, which is responsible for spreading information throughout the body. They are born during embryonic development and persist ...
Die Aufklärung eines neuartigen Pentose-Stoffwechsels und die Möglichkeit einer Homosuccinat-Fermentation in Darmbakterien
(2022-08-26)
In der vorliegenden Arbeit wurde der Pentose-Metabolismus des bedeutsamen Darmbakteriums Prevotella copri (P. copri) untersucht, und es wurde analysiert, ob die Umsetzung einer Homosuccinat-Fermentation mit dem Darmbakterium ......