E-Dissertationen: Search
Now showing items 1-10 of 49
Computational Exploration of Virus Diversity on Transcriptomic Datasets
(2019-11-21)
Most of the ongoing virus research is focused on mammalian and bird viruses, which are well known to be directly or indirectly associated with human diseases. While many viruses are transmitted by blood-feeding arthropods ...
First revision of the family Metarbelidae Strand, 1909 (Lepidoptera, Cossoidea Leach, 1815) and a phylogeny based on adult morphology of 60 genera from the Afrotropical and Oriental Region
(2019-08-19)
This thesis represents the first revision of the family Metarbelidae Strand, 1909. The author's extensive research on Metarbelidae includes fieldwork made in nine lowland and montane forests of Kenya (1994–2008; 2015–2018) ......
Erste Revision der Familie Metarbelidae Strand, 1909 (Lepidoptera, Cossoidea Leach, 1815) und die Phylogenie basierend auf der Adult-Morphologie von 60 Gattungen der Afrotropischen ......
Erste Revision der Familie Metarbelidae Strand, 1909 (Lepidoptera, Cossoidea Leach, 1815) und die Phylogenie basierend auf der Adult-Morphologie von 60 Gattungen der Afrotropischen ......
The role of Cysteine-rich with EGF-like domains 2 in the maintenance of metabolic homeostasis and regulation of the unfolded protein response
(2019-12-17)
Das Ziel dieser Arbeit war es, die Rolle von Creld2 bei der Aufrechterhaltung der metabolischen Homöostase unter Normalbedingungen und bei der Regulation der UPR unter ER Stressbedingungen zu untersuchen. Metabolische ...
Alternative splicing as a regulatory mechanism of the NLRP3 inflammasome
(2019-10-09)
The innate immune system relies on germ-line encoded pattern recognition receptors and is critically involved in the early sensing of pathogens and disturbances of cell homeostasis. Upon activation by pathogenic or sterile ...
The plesiosaur: remarkable morphology, histology, and physiology
(2019-07-04)
In this dissertation, contributions to understanding the morphology, histology, and physiology of plesiosaurs, a major group of marine reptiles from the Age of Dinosaurs, are presented. By using comparative methods and new ......
Application and Development of Mass Spectrometry-based Approaches to Investigate the Regulation of Lysosomal-associated Proteins by Phosphorylation
(2019-11-12)
Phosphorylation is one of the most abundant and best studied posttranslational modifications in mammalian cells and refers to the addition of a phosphate group to an amino acid residue of a protein. Phosphorylation can ...
Molecular and functional characterization of inflammation-induced cell state transitions in malignant-transformed melanocytes
(2019-10-08)
Cellular phenotype plasticity is a hallmark of embryonic development in order to achieve cell type specification from precursor populations. The molecular mechanisms orchestrating phenotypic plasticity are of interest ......
Platelet-immune cell interactions in inflammation and cancer
(2019-09-10)
Platelets are well-known for their role in hemostasis and only more recently, they have also been acknowledged for their immune regulatory roles. Despite being small sized and anucleated, they can respond to inflammatory ...
The differential regulation of podosome formation by Cytohesin-2 is mediated via α5β1 integrin and the small GTPase RhoA
(2019-09-25)
The interaction of a cell with the surrounding tissue is crucial not only to provide mechanical stability but also to enable adaptation of cellular responses to the environment. Recognition of extracellular matrix (ECM) ...
Characterization of VKORC1L1 with respect to VKORC1
(2019-07-10)
Vitamin K reduction is essential and catalyzed by two enzymes in vitro. Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) reduces vitamin K to sustain γ-carboxylation of vitamin K dependent (VKD) proteins. This ...
