Medizinische Fakultät: Medizinische Fakultät: Neuzugänge
Anzeige der Dokumente 321-340 von 2398
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Across Diagnostic Boundaries: Genetic Variants for Neuropsychiatric Disorders and their Association with Human Brain Structure
(2025-08-11)With the advances in genome-wide association studies (GWAS), hundreds of genetic variants have been identified for neuropsychiatric disorders. Strikingly, many of these genetic variants showed complex associations across ... -
NIS-Seq enables cell-type-agnostic optical perturbation screening
(2024-12-19)Optical pooled screening offers a broader-scale alternative to enrichment-based perturbation screening, using fluorescence microscopy to correlate phenotypes and perturbations across single cells. Previous methods work ... -
Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei
(2024-12-10)<strong>Background:</strong> <em>Mansonella perstans</em> is transmitted by <em>Culicoides</em> species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis ... -
Comparative Analysis of Shear Bond Strength in Orthodontic Brackets Between Milled and 3D-Printed Definitive CAD/CAM Restorations
(2024-10-18)<strong>Objective:</strong> The objective of this study was to evaluate the effect of different surface treatment methods on the shear bond strength (SBS) of metal brackets bonded to two types of CAD/CAM composite restorations: ... -
Schistosomiasis–Microbiota Interactions: A Systematic Review and Meta-Analysis
(2024-10-16)Introduction: Schistosomiasis, a tropical disease affecting humans and animals, affected 251.4 million people in 2021. <em>Schistosoma mansoni, S. haematobium, S. intercalatum</em>, and <em>S. japonicum</em> are primary ... -
Entwicklung und Validierung eines Screeninginstrumentes zur Diagnose einer Sepsis nach Schlaganfall
(2025-08-08)Schlaganfall-assoziierte Infektionen können eine Sepsis hervorrufen, die mit einem schlechten klinischen Outcome assoziiert ist. Die lebensbedrohliche Organdysfunktion, welche die Sepsis definiert, kann mittels Sequential ... -
Single-neuron representations of odours in the human brain
(2024-10-09)Olfaction is a fundamental sensory modality that guides animal and human behaviour. However, the underlying neural processes of human olfaction are still poorly understood at the fundamental—that is, the single-neuron—level. ... -
Mikrobielle Kontamination auf temporären Herzschrittmacher-Elektroden nach Transkatheter-Aortenklappen-Implantation und deren Einfluss auf klinischen Verlauf
(2025-08-08)Hintergrund und Zielsetzung: <br/> Die Transkatheter-Aortenklappenimplantation (TAVI) ist eine etablierte Behandlungsoption für Patienten mit symptomatischer, hochgradiger Aortenklappenstenose – unabhängig vom chirurgischen ... -
Microbial Spectrum, Intraoperative Findings, and Postoperative Outcomes in Native Knee Joint Infections: A Retrospective Analysis
(2024-12-16)<strong>Background:</strong> Native knee joint infections, while uncommon, present a serious condition predominantly instigated by bacteria such as <em>Staphylococcus aureus</em>. Without timely intervention, they can ... -
From Language Models to Medical Diagnoses: Assessing the Potential of GPT-4 and GPT-3.5-Turbo in Digital Health
(2024-12-02)Background: Large language models (LLMs) like GPT-3.5-Turbo and GPT-4 show potential to transform medical diagnostics through their linguistic and analytical capabilities. This study evaluates their diagnostic proficiency ... -
Characterization of the disorganization of the inner retinal layers in diabetics using increased axial resolution optical coherence tomography
(2025-01-13)<strong>Purpose:</strong> To compare a novel high-resolution optical coherence tomography (OCT) with improved axial resolution (High-Res OCT) with conventional spectral-domain OCT (SD-OCT) with regard to their capacity to ... -
Barriers and Facilitators of Patient Engagement Activities to Improve Patient Safety in Healthcare Organizations: A Delphi-Based Expert Survey
(2024-12-19)<strong>Purpose:</strong> In order to obtain sustainable healthcare, engagement of patients in patient safety improvement is vital. Drawing upon a multi-perspective approach, this study aimed to investigate perspectives ... -
Mind wandering, poor sleep, and negative affect: a threefold vicious cycle?
(2024-09-05)Mind wandering (MW) is intricately linked to sleep and affect, bearing clinical relevance for various psychiatric conditions, notably attention deficit/hyperactivity disorder, depression, and anxiety disorders. Most reviews ... -
Brain and Ventricle Volume Alterations in Idiopathic Normal Pressure Hydrocephalus Determined by Artificial Intelligence-Based MRI Volumetry
(2024-07-03)The aim of this study was to employ artificial intelligence (AI)-based magnetic resonance imaging (MRI) brain volumetry to potentially distinguish between idiopathic normal pressure hydrocephalus (iNPH), Alzheimer's disease ... -
Comorbidity profiles among sputum-positive tuberculosis patients in Cameroon
(2024-10-02)<strong>Introduction:</strong> Comorbid non-communicable diseases (NCDs) like diabetes, cardiovascular diseases (CVD), kidney diseases, and hypertension, could have implications for tuberculosis (TB) treatment management ... -
Innovative Regional Services and Heterogeneous Communication Channels: Results from the Nationwide German egePan Project for Pandemic Management
(2024-11-04)<strong>Background:</strong> In the COVID-19 pandemic, novel regional services and communication channels emerged across all sectors of the German healthcare system. To contribute to pandemic preparedness, this study aims ... -
Expressionsmodulation der Hitzeschockproteine HSP27 und HSP70 in malignen Zellen nach Exposition gegenüber nicht-invasivem physikalischem Plasma
(2025-08-05)Aufgrund seines vor allem wachstumshemmenden Effekts auf maligne Zellen gilt Nicht-invasives physikalisches Plasma (NIPP) als vielversprechende Therapieoption in der Onkologie. <br/> Aktuelle Studien konnten eine Beteiligung ... -
Reproduzierbarkeit der quantitativen Auswertung der PSMA-PET
(2025-08-05)<strong>Hintergrund:</strong> Bei Patienten mit Prostatakarzinom, die eine PSMA-gerichtete Radioligandentherapie (RLT) erhalten, korrelieren höhere SUV-Werte mit besseren Therapieergebnissen. Daher ist es entscheidend, die ... -
Investigation and discovery of targetable markers in urological tumors
(2025-08-05)Urological cancers are among the cancers with the highest incidence. In recent years, several therapeutic solutions have been suggested and accepted in the clinic for treatment, but tumors, especially the most aggressive ... -
AIM2-Inhibitory Nanobodies Reveal Differential Activation of AIM2 and NLRP3 Inflammasomes by Poxvirus DNA Genomes in Primary Human Cells
(2025-08-05)Poxviruses are large double-stranded (ds)DNA viruses that replicate in the cytoplasm. While variola virus (VARV) caused millions of deaths before its eradication in 1980, monkeypox virus (MPXV) has been declared a public ...
