Medizinische Fakultät: Medizinische Fakultät: Neuzugänge
Anzeige der Dokumente 521-540 von 2398
-
Treatment Effect of Budesonide in 5xFAD mouse model of Alzheimer´s disease
(2025-02-21)This project investigated the therapeutic potential of Budesonide, a glucocorticoid commonly used for asthma therapy, in the treatment of the 5xFAD mouse model of Alzheimer’s disease. The findings indicate that inhalation ... -
Intrinsic and extrinsic mechanisms involved in treatment resistance and progression of bladder and prostate cancers
(2025-02-21)Prostate cancer (PCa) and urothelial cancer (UC) are the most commonly diagnosed urological cancers. Advanced PCa and UC are significant causes of cancer-related deaths. Effective treatment of advanced PCa and UC remains ... -
Die Rollen der Hausärzt*innen in der COVID-19 Pandemie: Engagement und Erfahrungen
(2025-02-20)Hausärzt*innen leisteten einen wesentlichen Beitrag zur Bekämpfung der COVID-19 Pandemie und Aufrechterhaltung des Gesundheitssystems. Dennoch ist wenig über ihre Rolle, ihre Führungsqualität, ihre Beteiligung an regional ... -
Sport bei der emotional instabilen Persönlichkeitsstörung: Wie wirkt sich eine einmalige Sportintervention verschiedener Intensitäten auf psychologische und physiologische Marker von Stress, Kognition und Emotionalität aus?
(2025-02-19)Pathologien im affektiven, kognitiven und interpersonellen Verhalten sind typische Symptome bei Betroffenen der emotional instabilen Persönlichkeitsstörungen (BPS) (WHO, 2022). Auf Grund des hohen Leidensdrucks und häufiger ... -
Evolving the Era of 5D Ultrasound?: A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology
(2023-10-29)Artificial intelligence (AI) has gained prominence in medical imaging, particularly in obstetrics and gynecology (OB/GYN), where ultrasound (US) is the preferred method. It is considered cost effective and easily accessible ... -
Comparison between regular additional endobiliary radiofrequency ablation and photodynamic therapy in patients with advanced extrahepatic cholangiocarcinoma under systemic chemotherapy
(2023-08-29)<strong>Background and aims: </strong>Extrahepatic cholangiocarcinoma (eCCA) remains a malignancy with a dismal prognosis. The first-line standard of care includes systemic chemotherapy (SC) and biliary drainage through ... -
Acceptability of surgical care in Uganda: a qualitative study on users and providers
(2023-07-31)<strong>Objectives</strong> This study was conducted to assess acceptability of surgical care in Eastern Uganda and enable better allocation of resources, and to guide health policy towards increased surgical care seeking.<br ... -
Electrophysiological evidence for increased auditory crossmodal activity in adult ADHD
(2023-08-29)<strong>Background:</strong> Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by core symptoms of inattention, and/or impulsivity and hyperactivity. In order to understand ... -
Finding gut microbiome signature in clinical intervention trials
(2025-02-17)The gut microbiome plays a crucial role in the gut brain axis, especially by modulating the immune system, influencing metabolism, protecting against pathogens, and impacting mental well-being. Therefore, it can be modulated ... -
Deciphering the regulation of tissue adaptation of regulatory T cells
(2025-02-17)Regulatory T (Treg) cells are specialised immune cells of the CD4<sup>+</sup> T cell lineage that are indispensable for the maintenance of immune homeostasis and prevention of immune-mediated pathology. Most Treg cells ... -
Local synthesis of steroid hormones in human hair roots
(2025-02-17)Hair loss displays a common symptom with a multitude of different origins that complexes diagnostics and therapy. <br /> The basis of the current project was the hypothesis, that hair loss may be correlated or even ... -
Neurogenic Lower Urinary Tract Symptoms, Fatigue, and Depression — Are There Correlations in Persons with Multiple Sclerosis?
(2023-08-04)The symptoms of multiple sclerosis (MS) frequently include fatigue, depression, and neurogenic lower urinary tract symptoms (LUTS), causing severe burdens on affected individuals. The relationships between these symptoms ... -
German GPs’ Self-Perceived Role in the COVID-19 Pandemic: Leadership, Participation in Regional Services and Preferences for Future Pandemic Preparedness
(2023-06-09)General practitioners (GPs) played a vital role during the COVID-19 pandemic. Little is known about GPs’ view of their role, leadership, participation in regional services and preferences for future pandemic preparedness. ... -
The role of primary cilia in controlling metaflammation
(2025-02-14)The primary cilium is a cellular antenna that senses and integrates external stimuli. Its composition is regulated by specialized proteins, such as BBS proteins, and mutations in any of the genes that encode BBS proteins ... -
Dauerbelastungen von vorgefertigten Stegen auf einteiligen Dentalimplantaten
(2025-02-14)In der vorliegenden Arbeit wurden In vitro-Ermüdungsstests an vorgefertigten Stegen auf zwei verschiedenen Implantatsystemen durchgeführt. Getestet wurde nach den Vorgaben in EN ISO 14801. Dementsprechend wurden die ... -
Abgrenzung unterschiedlicher Subtypen des Mastzellaktivierungssyndroms mithilfe einer Clusteranalyse: Eine retrospektive Analyse
(2025-02-13)Die vorliegende Arbeit behandelt die erstmalige Anwendung von Cluster- und Assoziationsanalysen beim Mastzellaktivierungssyndrom. Bei diesem handelt es sich um eine bisher wenig erforschte, schwer greifbare Erkrankung mit ... -
Bildgebende Biomarker bei degenerativen Ataxieerkrankungen
(2025-02-13)Bildgebende Biomarker bei degenerativen Ataxieerkrankungen haben in den sporadischen Ataxien des höheren Erwachsenenalters ein hohes diagnostische Potential und sind bei erblichen Ataxien, wichtige Parameter zur Beurteilung ... -
Immunotherapy-based targeting of senescent cells
(2025-02-12)Cellular senescence is a state of permanent cell cycle arrest, characterized by substantial macromolecular alterations and senescence-associated secretory phenotype (SASP) in response to various stressors. The accumulation ... -
Die Bedeutung von TLR9 für die inflammatorische Reaktion im Herz nach CASP induzierter Sepsis
(2025-02-12)Die Sepsis ist nach dem Herzinfarkt und Tumorerkrankungen an dritter Stelle der häufigsten Todesursachen in Deutschland. Bedingt durch unsere alternde Gesellschaft, der steigenden Zahl antibiotikaresistenter Keime und dem ...
