E-Dissertationen: Browsing E-Dissertationen by Title
Now showing items 378-397 of 4163
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Biodiversity of Marine Heterobranchia (Gastropoda) around North Sulawesi Indonesia
Undap, Nani Ingrid Jacquline (2020-07-24)North Sulawesi province is one of the most potential areas in terms of natural marine resources. In North Sulawesi there are many interesting tourist places with high marine biodiversity and many objects are currently under ... -
Biodiversity patterns of herbivore scarab chafers of Sri Lanka with particular reference to DNA based species delimitation, taxonomy, morphospace, and assemblage composition (Coleoptera: Scarabaeidae)
Ranasinghe, Sasanka (2022-11-15)Describing and analysing biodiversity and its major patters is key to investigate the underlying processes and causes of diversification. Biodiversity analysis requires proper species inference, knowledge of species ... -
Die Biogenese der Haut: Etablierung von mRNA Expressionsprofilen von proliferierenden und differenzierenden Keratinozyten unter Einfluss von Stickstoff Monoxid und Untersuchung einer Glucosylceramide Synthase defizienten Maus
Gallala, Hichem D. (2007)Die Epidermis ist ein sehr komplexes Organ. Es besteht aus Zellen die sich in unterschiedlichen Phasen ihres Zyklus befinden. Die Zellen in der untersten Schicht der Haut (Basalschicht) befinden sich im Prozess der ... -
Biogeographical Analyses and Applications: The Study of Plant Distribution Patterns in West Africa
García Márquez, Jaime Ricardo (2011-03-10)Studies and applications in biogeography aim at understanding the causes and determinants of past, current, and future diversity distribution patterns. In this context, niche models are currently important tools. They make ... -
Biogeography and Diversity Hotspots of Larger Indo-Pacific Foraminifera: A Structural Faunal Analysis from Raja Ampat
Förderer, Esther-Meena (2018-07-05)This thesis is the first comprehensive study on the species-rich benthic foraminiferal fauna of Raja Ampat (Indonesia) and the first to evaluate the biogeographic richness patterns and faunal provinces of recent Indo-Pacific ... -
Biogeomorphic dynamics in the Turtmann glacier forefield, Switzerland
Eichel, Jana (2017-05-19)Worldwide, glacier retreat enlarges glacier foreland areas, which are characterized by pronounced geomorphic and ecologic dynamics. Feedbacks between these dynamics are believed to drive glacier foreland landscape development, ... -
Bioinformatische und in-vitro-Analyse der frs-Biosynthesegencluster von Cand. Burkholderia crenata und Chromobacterium vaccinii
Schamari, Isabella (2019-07-03)<p>FR900359 (FR) ist ein selektiver G<sub>q</sub>-Proteininhibitor, der ursprünglich aus der Pflanze <em>Ardisia crenata</em> isoliert wurde. G-Proteine spielen eine zentrale Rolle in der Signalübertragung von ... -
Biological Evaluation of Serine Protease Inhibitors and Inducers of Protein Degradation
Mangold, Martin (2020-10-02)Serine proteases represent the largest group of enzymes of the human degradome. As such, they are valuable targets for the development of new drugs, due to their involvement in several diseases. Over the course of this ... -
Biological functions of Sphingomyelin synthase related protein and Ceramide synthase 4 investigated with transgenic mouse mutants
Bickert, Andreas (2017-01-04)Previously, it was reported that the catalytic activity of the sphingomyelin synthase related protein (SMSr) is essential to prevent ceramide accumulation and disruption of the early secretory pathway in cultured HeLa ... -
Biologicals and Biosimilars: Differences and implementation of the regulatory requirements in the European Union versus those in the United States with special consideration and analysis of the implementation and improvement of safety standards for biosimilar products
Schulzensohn, Marlene (2018-06-08)What safety relevant standards are established for biotechnology-derived biosimilar products in both the European Union (EU) and the USA? And, is there potential to improve the current safety standards? The applicable ... -
Die biologische Funktion der N1-2´O-Methylierung eukaryotischer mRNA durch die Methyltransferase CMTr1
Wolter, Steven (2021-05-14)Eukaryoten modifizieren das 5´-Ende ihrer mRNA mit einem invertierten N7-methyliertem Guanosin (m7G). Diese Cap0 genannte Struktur wird in höheren Eukaryoten durch die Methyltransferase CMTr1 weiter modifiziert: CMTr1 ... -
Biomechanische Untersuchungen zur Rolle des Zytoskeletts für die mechanische Anisotropie und Dehnbarkeit von Monolagen epithelialer Zellen
Ahrens, Dave (2019-08-29)<p>Die Haut ist eines der faszinierendsten Organe des menschlichen Körpers. Kenntnisse über ihre mechanischen Eigenschaften sind insbesondere in der Medizin von hoher Relevanz, wie z.B. während chirurgischer Eingriffe oder ... -
Biometric Cryptosystems: Authentication, Encryption and Signature for Biometric Identities
Sarıer, Neyire Deniz (2013-04-12)Biometrics have been used for secure identification and authentication for more than two decades since biometric data is unique, non-transferable, unforgettable, and always with us. Recently, biometrics has pervaded other ... -
Biopharmaceutical characterization and formulation development of poorly water-soluble phytochemicals using in vivo predictive biphasic dissolution
Brenner, Marvin Benedikt (2024-05-22)Nature offers a vast variety of different substances, some of which are known to have health-beneficial effects on humans. Thus, many of these compounds are frequently used as dietary supplements or herbal medicinal products. ... -
Biophysical analysis of protein-protein and protein-small molecule interactions
Albertoni, Barbara (2011-11-29)The validation of small molecule inhibitors identified by high throughput screening requires a set of robust assays for interaction analysis. Here I describe the implementation of three methods: bioluminescence resonance ... -
Biophysical studies of EGFR conformation and interaction
Yin, Dongsheng (2019-03-26)Epidermal growth factor receptor (EGFR) plays such a crucial role in cell signaling that its activity is intricately regulated. According to the prevailing activation model, EGF binding to EGFR initiates a series of ... -
Bioprocess Development for the Generation of Monocyte-derived Dendritic Cells: Applicability in Breast Cancer Immunotherapy
Bohnenkamp, Hermann Richard (2004)Monocyte-derived dendritic cells (DCs) are currently under extensive evaluation as cell vaccines for cancer treatment. The requirement for large-scale cell products demands optimized and standardized protocols. This study ... -
Die Biosynthese des Vitamin B6 und des Gingotoxins als Beispiel einer Konvergenz: Klonierung und Expression eines sor-homologen Gens aus Ginkgo biloba L., Ginkgoaceae
Genau, Andreas (2002)Mit den Ergebnissen zur Biosynthese des Vitamin B6 in verschiedenen Organismen haben sich in den letzten Jahren zahlreiche neue Aspekte eröffnet. Ging man zuvor davon aus, alle zur Biosynthese befähigten Organismen ... -
Biosynthese und Analytik von Sesquiterpenen in Weinbeeren (Vitis vinifera)
May, Bianca (2016-05-17)Mit dem Sesquiterpen Rotundon wurde 2008 erstmals ein Sesquiterpen als Schlüsselaromastoff im Wein identifiziert. Bis dato lagen nur wenige Informationen zu Sesquiterpenen in <em>Vitis vinifera </em>vor. Ziel dieser Arbeit ... -
Die Biosynthese und der Transport von N-Acetylaspartylglutamat und N-Acetylaspartylglutamylglutamat
Lodder-Gadaczek, Julia Aletta Kathrina (2013-07-10)N-Acetylaspartylglutamat (NAAG) ist eines der höchst konzentrierten Neuropeptide im Nervensystem von Säugetieren. Neben der postulierten Rolle als Agonist für den Typ II metabotropen Glutamatrezeptor 3. Zusätzlich dient ...