E-Dissertationen: Search
Now showing items 11-20 of 303
Rolle der Aktivierung des Peroxisome proliferator-activated receptor gamma durch Pioglitazon in der hepatischen Immunregulation
(2012-02-17)
Der Peroxisome proliferator-activated receptor gamma (PPARγ) gehört zur Superfamilie nukleärer Faktoren, die nach Ligandenbindung Genexpression regulieren. PPARγ steuert durch Bindung an PPARγ-responsive Elemente die ......
Peroxisome proliferator-activated receptor gamma (PPARγ) belongs to the superfamily of nuclear receptors regulating gene expression upon ligand binding. After binding to responsive elements PPARγ induces the expression of ......
Peroxisome proliferator-activated receptor gamma (PPARγ) belongs to the superfamily of nuclear receptors regulating gene expression upon ligand binding. After binding to responsive elements PPARγ induces the expression of ......
Measurement of the double polarization observables G and E in neutral and positive pion photoproduction off the proton
(2020-08-14)
The nucleons, as one of the most fundamental building blocks of visible matter, are built up of quarks and gluons. However, the interactions and dynamics inside the nucleons, which are mediated by the strong force and ......
Einträge, Vorkommen, Verbreitung und gesundheitliche Bedeutung antibiotikaresistenter Bakterien in Abwasser und Gewässern: Ein sozial-ökologischer Beitrag zur Geographischen Gesundheitsforschung
(2011-11-29)
Antibiotika gelangen über natürliche Ausscheidung von Mensch und Tier sowie unsachgemäße Entsorgung in die Umwelt. Wichtige Eintragspfade stellen Abwasser, Klärschlamm und Gülle dar. Mikroorganismen können Resistenzen gegen ...
Benzimidazol-Analoga als Modulatoren von ABC-Transportern
(2011-10-17)
Humane ABC-Transporter (ATP-Binding-Casette) wie P-Glykoprotein (P-gp), die Multidrug Resistance associated Proteine (MRPs) oder Breast Cancer Resistance Protein (BCRP) stellen für die Arzneimitteltherapie einen sehr ...
Integrating the Pharmacist into Cancer Medication Management
(2012-01-06)
Aim: The present study aimed at evaluating the integration of the pharmacist in multiprofessional cancer care.
Methods: Part I: Two pharmaceutical care services for cancer patients were compared. One was provided ...
Methods: Part I: Two pharmaceutical care services for cancer patients were compared. One was provided ...
Untersuchung des Wirkmechanismus von Peptidantibiotika an simulierten bakteriellen Membranen mit Hilfe von Biosensortechniken
(2011-12-12)
In der vorliegenden Dissertation wird eindrucksvoll das Potential der biosensorischen Messmethoden (Quarzmikrowaage, akustischer Oberflächenwellensensor, Zyklische Voltammetrie und Isothermale Titrationskalorimetrie) bei ...
Veränderung der Tablettiereigenschaften von Trockengranulaten aus Mikrokristalliner Cellulose durch Zusatz verschiedener Hilfsstoffe
(2011-12-07)
In dieser Arbeit wurde untersucht, wie sich die Tablettiereigenschaften von Trockengranulaten durch Zusatz verschiedener Hilfsstoffe verhalten. Als Standardsubstanz wurde dafür die Mikrokristalline Celluse (MCC) Typ 105 ...
Analysis of the genetic potential of the spongederived fungus Penicillium chrysogenum E01-10/3 for polyketide production
(2011-03-14)
The main goal of the presented dissertation was to evaluate the genetic potential of P. chrysogenum E01-10/3 strain for the production of polyketides.
This marine-derived P. chrysogenum strain was isolated from the ...
This marine-derived P. chrysogenum strain was isolated from the ...
Comparison of a global submission of new biological entity and a new chemical entity: strategic decisions and criteria for implementation
(2011-06-09)
The world covers more than 190 countries in which at the moment in most of them pharmaceutical legislations and regulatory requirements are established and implemented, e.g. to describe the marketing authorization (MA) ...
Multi-stage Micropattern Gaseous Detectors for the ALICE TPC Upgrade - Studying and Modelling Charge Transfer and Energy Resolution
(2020-06-23)
With the upgrade of the LHC (Large Hadron Collider) at CERN, the interaction rate of ALICE
(A Large Ion Collider Experiment) will be increased up to 50 kHz for Pb-Pb collisions.
Thus the gated and rate-limited readout ...