E-Dissertationen: Suche
Anzeige der Dokumente 951-960 von 1173
Untersuchungen zum Metabolismus und Nachweisfenster von γ-Hydroxybuttersäure in biologischem Material
(2018-03-19)
In dieser Arbeit wurden interdisziplinäre Untersuchungen durchgeführt, um die Nachweisbarkeitsdauer nach einer Gamma-Hydroxybuttersäure-(GHB)-Gabe in biologischen Matrices zu verlängern. Es sollten biologische Marker ...
Fast detection of protein-protein interactions with an automated FRET-based system on the flow cytometer
(2018-03-12)
Although protein-protein interactions play a major role in almost all biological functions, those interactions cannot easily be analysed, especially not on single cell level and with regard to dynamic changes in protein ...
Lipide als Transport- und Signalmoleküle: Untersuchungen in Makrophagen und Neuronen
(2018-04-17)
Lipide haben einen großen Anwendungsbereich und speziell in der Biochemie des lebenden Organismus wichtige Funktionen. Neben ihrer hauptsächlichen Funktion als Energiespeicher und Strukturkomponenten der Zellmembranen ...
Physiological, biochemical and molecular responses of different barley varieties to drought and salinity
(2018-03-02)
Barley (Hordeum vulgare) is an important member of grass family Poaceae. Among various agricultural crops, barley is considered a model plant due to its important features like short season, tolerance to abiotic stress, ...
The importance of endogenous opioids in feeding behavior
(2018-03-14)
Endogenous opioids are involved in a broadly distributed neural network regulating eating behavior. Opioid transmission has long been implicated in controlling hedonic and homeostatic feeding as well as regulating body ......
Application of BioID to in vitro organelle and in vivo cell-type-specific proteomics
(2020-09-17)
A genetically modified biotin ligase BirA (Arg118Gly), termed BioID (BirA*), can be induced to add a reactive form of biotin to proximate proteins in the cytosol and nucleus. The biotinylated proteins can be purified and ......
Functional cooperation of Toll-like receptor signaling and the high-affinity receptor for IgE, FcεRI, on human Langerhans cells
(2018-01-15)
Atopic dermatitis (AD) is a multifactorial severe skin disease with increasing incidence in western countries. In the disease, Langerhans cells (LC) play a pivotal role in bridging innate and adaptive immunity through ......
The endophytic fungus Stemphylium globuliferum – secondary metabolites and biological activities
(2018-01-22)
Fungi are a tremendous source of pharmaceutically significant compounds, e.g. the life saving immunosuppressant drug mycophenolic acid. The current project focused on the investigation of the mold fungus Stemphylium ......
Optimierung der mikrobiellen Produktion von präbiotischen Zuckerderivaten auf Levan-Basis
(2021-04-21)
Die vorliegende Arbeit befasste sich mit der Entwicklung und Optimierung einer mikrobiellen Produktionsstrategie zur Synthese ß-2,6-glykosidisch verknüpfter Fruktane. Levan (ß-2,6-glykosidisch verknüpftes Fruktan) und ......
Untersuchungen zur heterologen Biosynthese des seltenen kompatiblen Soluts Nε-Acetyl-β-Lysin
(2020-08-28)
Das Aminosäurederivat Nε-Acetyl-β-Lysin (NAβL) wird von methanogenen Archaeen und einigen Vertretern der Bakterien zur Anpassung an osmotischen Stress produziert. Bisher wurden vor allem die zur Produktion ......
Studies on the heterologous biosynthesis of the rare compatible solute Nε-acetyl-β-lysine
The amino acid derivative Nε-acetyl-β-lysine (NAβL) is produced by methanogenic ......
Studies on the heterologous biosynthesis of the rare compatible solute Nε-acetyl-β-lysine
The amino acid derivative Nε-acetyl-β-lysine (NAβL) is produced by methanogenic ......