Faculties of University Bonn: Fakultäten der Universität Bonn: Recent submissions
Now showing items 161-180 of 9522
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Linguistically Aware and Augmentation-Driven Methods for Enhancing Natural Language Understanding
(2025-07-22)Current large language models excel in solving numerous complicated tasks, but are primarily optimized for the English language and popular application domains, delivering sub-optimal outputs for low-resource languages and ... -
Gender, Gender (In)Equality, and Small-holder farming in Northern Ethiopia: Discourses and Practices
(2025-07-21)This research unravels the ways in which gender is understood, articulated, and enters into small holder farming in Ethiopia and how these conceptions, understandings, and articulations create and re-create a system of ... -
One-dimensional aggregates of the organic dye quinacridone on metallic and dielectric surfaces
(2025-07-21)The present work deals with the question to what extent the motif of intermolecular hydrogen bonds (H-bonds) can be used to generate isolated one-dimensional (1D) structures, i.e. "chains", of organic molecules on surfaces ... -
Regenerative Parodontalchirurgie und kieferorthopädische Zahnbewegung bei Stadium IV Parodontitis: Ergebnisse klinischer Studien
(2025-07-21)Parodontitis im Stadium IV ist charakterisiert durch schweren Verlust an parodontalem Attachment, vertikale Knochendefekte und pathologische Zahnwanderung (PTM). Die Komplexität des Krankheitsbildes aufgrund von PTM - ... -
Development of Histone Deacetylase Inhibitors and Degraders with Antiplasmodial and Anticancer Activity
(2025-07-21)Histone deacetylases (HDACs) are key targets in epigenetic drug discovery, as they catalyze the removal of acetyl and acyl groups from lysine side chains of histones and other proteins, thereby influencing gene expression ... -
Morphologic adaptations and hydrodynamics of 'pelvic brooding', a derived reproductive strategy in Sulawesi ricefishes (Beloniformes: Adrianichthyidae)
(2025-07-18)(noch nicht zugänglich / not yet accessible) -
Associated production of a top-quark and a Higgs-boson in the H→ττ decay channel in pp collisions at √s = 13 TeV using the ATLAS detector
(2025-07-18)Since the discovery of the Higgs-boson in 2012, experiments at the LHC have focused on studying and precisely measuring this particle's properties. Of particular interest is the Yukawa coupling between the Higgs-boson and ... -
Leader Effectiveness - (Not) Always Look on the Bright Side of Leader Traits: Kurvilineare Zusammenhänge von grandiosem Narzissmus und Ehrlichkeit-Bescheidenheit mit Führungseffektivität
(2025-07-18)Die bisherige Forschung zu grandiosem Narzissmus und Ehrlichkeit-Bescheidenheit lieferte erste Hinweise auf kurvilineare Zusammenhänge mit Führungseffektivität, die implizieren, dass extreme Ausprägungen in den ... -
Molekulargenetische Verfahren zur Untersuchung der Patienten- und Umgebungsmikrobiom-assoziierten Krankheitsentstehung und -dynamik
(2025-07-18)Die präsentierten Ergebnisse unterstreichen die Bedeutung des Mikrobioms nicht nur als Indikator für gesundheitliche Zustände, sondern auch als aktiven Teilnehmer in der Krankheitsentwicklung. Durch die detaillierte Analyse ... -
Towards a Network Approach: Production Environments of Digital Innovation in the Global South and their Function in Social Transformation Processes
(2025-07-18)This thesis deals with production environments of digital innovations in the Global South and their impact on social transformation processes. Production environments are understood as networks that ultimately influence ... -
Development and Characterization of an Irradiation Site for Radiation Damage Studies of the ATLAS ITk Pixel Detector
(2025-07-17)Silicon pixel detectors build the foundation of particle tracking in high-rate environments, delivering high spatial resolution while sustaining hit rates of up to several GHz cm<sup>-2</sup>. In the field of modern-day ... -
A likely role for stratification in present-day changes of the global ocean tides
(2025-07-16)Ocean tides are a phenomenon familiar to the general society, as they are observable in almost any coastal area. The regular rise and fall of the global oceans, caused by the gravitational attraction of Sun and Moon, affects ... -
Attention Deficit Hyperactivity Disorder: A Risk Factor for Premature Discontinuation of Inpatient Opioid Withdrawal Treatment
(2024-06-03)<strong>Background:</strong> Substance use disorders present a tremendous challenge within contemporary healthcare systems. Specifically, in the domain of opioid use disorders (OUDs), several foundational elements are ... -
Severe autoimmune hemolytic anemia following immunotherapy with checkpoint inhibitors in two patients with metastatic melanoma: a case report
(2024-03-20)<strong>Introduction:</strong> Over the past decade, immune checkpoint inhibitors such as antibodies against cytotoxicity T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) have become ... -
Comparative development of human filariae Loa loa, Onchocerca volvulus and Mansonella perstans in immunocompromised mouse strains
(2024-04-15)<strong>Introduction:</strong> Mouse models of human filarial infections are not only urgently needed to investigate the biology of the nematodes and their modulation of the host's immunity, but will also provide a platform ... -
Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis
(2024-03-25)During embryogenesis, the fetal liver becomes the main hematopoietic organ, where stem and progenitor cells as well as immature and mature immune cells form an intricate cellular network. Hematopoietic stem cells (HSCs) ... -
The unusual mode of action of the polyketide glycoside antibiotic cervimycin C
(2024-05-09)Cervimycins A–D are bis-glycosylated polyketide antibiotics produced by <em>Streptomyces tendae</em> HKI 0179 with bactericidal activity against Gram-positive bacteria. In this study, cervimycin C (CmC) treatment caused a ... -
The role of dendritic cells in MASH: friends or foes?
(2024-04-08)Dendritic cells (DCs) are major antigen-presenting cells that connect innate and adaptive immunity. Hepatic DCs are less activated and contribute to maintain the tolerogenic environment of the liver under steady state. ... -
Vermarktungsstrategien von Aquaponik-Produkten: Analyse von Erfolgsfaktoren
(2025-07)Aquaponik gilt als ein nachhaltiges System der Produktion von Fischen und Pflanzen. Es kann vor diesem Hintergrund zu einer Vernachhaltigung der Lebensmittelerzeugung beitragen. <br /> Basierend auf einer Analyse der ... -
Generation of a Generic Nanobody-based CAR-T Cell Platform
(2025-07-16)Recent advances in cancer therapy, particularly immune checkpoint blockade (ICB), have significantly improved immune responses against tumors. However, many patients do not respond to ICB, and some experience disease ...
