Medizinische Fakultät: Medizinische Fakultät: Neuzugänge
Anzeige der Dokumente 101-120 von 1983
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RIG-I-like receptors in aortic inflammation and calcification
Gräf, Madeleine (2025-02-26)It has been already well established that erroneous detection of endogenous nucleic acids by the innate immune system drives pathogenic processes of autoimmunity. Along with that, gain-of function mutations in the RIG-I-like ... -
Investigating the Role of Nucleic Acid Sensing in the Pathogenesis of Chronic Viral Infection-Induced Chronic Kidney Disease and Autoimmunity
Kho, Christabel Celia (2025-02-25)Patients with chronic HIV infections, are at increased risk of developing comorbidities, with chronic kidney disease (CKD) such as immune complex glomerulonephritis (ICGN) being particularly common. Diagnosis of ICGN ... -
Zahnbehandlungsangst in Abhängigkeit von einer ausführlichen Aufklärung vor der Behandlung bei Füllungstherapie-Patienten
Schmidt, Ursula (2025-02-25)In einer allgemeinzahnärztlichen Praxis wurden 99 Patienten vor einer anstehenden Füllungstherapie mittels eines standardisierten Fragebogens nach ihrer Zahnbehandlungsangst befragt. Vor der Beantwortung des Fragebogens ... -
Der Einfluss der SARS-CoV-2-Pandemie und behördlichen Maßnahmen auf Angstsymptome und depressive Symptome bei psychiatrischen Erkrankungen
Blazejak, Alexander (2025-02-25)Eine Stichprobe von 115 erwachsenen Proband*innen wurde prospektiv über drei Zeiträume im ersten Jahr der SARS-CoV-2-Pandemie untersucht. Mithilfe etablierter Skalen wurde der Einfluss der medial kommunizierten Pandemie ... -
Untersuchung der Beteiligung der Rho-Kinase und der reaktiven Sauerstoffspezies an der Autophagie-Regulation durch Druckbelastung in PDL-Zellen
Hardt, Miriam (2025-02-25)Die Autophagie ist ein komplexer zellulärer Selbstverdauungsmechanismus, der mit Zellstress in Zusammenhang steht. Sie kann durch Aufrechterhaltung der zellulären Homöostase das Überleben von Zellen ermöglichen oder in den ... -
Treatment Effect of Budesonide in 5xFAD mouse model of Alzheimer´s disease
Yang, Xu (2025-02-21)This project investigated the therapeutic potential of Budesonide, a glucocorticoid commonly used for asthma therapy, in the treatment of the 5xFAD mouse model of Alzheimer’s disease. The findings indicate that inhalation ... -
Intrinsic and extrinsic mechanisms involved in treatment resistance and progression of bladder and prostate cancers
Hosni, Sana (2025-02-21)Prostate cancer (PCa) and urothelial cancer (UC) are the most commonly diagnosed urological cancers. Advanced PCa and UC are significant causes of cancer-related deaths. Effective treatment of advanced PCa and UC remains ... -
Die Rollen der Hausärzt*innen in der COVID-19 Pandemie: Engagement und Erfahrungen
Kugai, Simon Saburo (2025-02-20)Hausärzt*innen leisteten einen wesentlichen Beitrag zur Bekämpfung der COVID-19 Pandemie und Aufrechterhaltung des Gesundheitssystems. Dennoch ist wenig über ihre Rolle, ihre Führungsqualität, ihre Beteiligung an regional ... -
Sport bei der emotional instabilen Persönlichkeitsstörung: Wie wirkt sich eine einmalige Sportintervention verschiedener Intensitäten auf psychologische und physiologische Marker von Stress, Kognition und Emotionalität aus?
Wanka, Lina (2025-02-19)Pathologien im affektiven, kognitiven und interpersonellen Verhalten sind typische Symptome bei Betroffenen der emotional instabilen Persönlichkeitsstörungen (BPS) (WHO, 2022). Auf Grund des hohen Leidensdrucks und häufiger ... -
Evolving the Era of 5D Ultrasound?: A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology
Jost, Elena; Kosian, Philipp; Jimenez Cruz, Jorge; Albarqouni, Shadi; Gembruch, Ulrich; Strizek, Brigitte; Recker, Florian (2023-10-29)Artificial intelligence (AI) has gained prominence in medical imaging, particularly in obstetrics and gynecology (OB/GYN), where ultrasound (US) is the preferred method. It is considered cost effective and easily accessible ... -
Comparison between regular additional endobiliary radiofrequency ablation and photodynamic therapy in patients with advanced extrahepatic cholangiocarcinoma under systemic chemotherapy
Möhring, Christian; Khan, Oliver; Zhou, Taotao; Sadeghlar, Farsaneh; Mahn, Robert; Kaczmarek, Dominik J.; Dold, Leona; Toma, Marieta; Marinova, Milka; Glowka, Tim; Matthaei, Hanno; Manekeller, Steffen; Kalff, Jörg C.; Strassburg, Christian; Weismüller, Tobias J.; Gonzalez-Carmona, Maria A. (2023-08-29)<strong>Background and aims: </strong>Extrahepatic cholangiocarcinoma (eCCA) remains a malignancy with a dismal prognosis. The first-line standard of care includes systemic chemotherapy (SC) and biliary drainage through ... -
Acceptability of surgical care in Uganda: a qualitative study on users and providers
Rauschendorf, Paula; Nume, Rosette; Bruchhausen, Walter (2023-07-31)<strong>Objectives</strong> This study was conducted to assess acceptability of surgical care in Eastern Uganda and enable better allocation of resources, and to guide health policy towards increased surgical care seeking.<br ... -
Electrophysiological evidence for increased auditory crossmodal activity in adult ADHD
Schramm, Mia; Goregliad Fjaellingsdal, Tatiana; Aslan, Behrem; Jung, Paul; Lux, Silke; Schulze, Marcel; Philipsen, Alexandra (2023-08-29)<strong>Background:</strong> Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by core symptoms of inattention, and/or impulsivity and hyperactivity. In order to understand ... -
Finding gut microbiome signature in clinical intervention trials
Mantri, Aakash (2025-02-17)The gut microbiome plays a crucial role in the gut brain axis, especially by modulating the immune system, influencing metabolism, protecting against pathogens, and impacting mental well-being. Therefore, it can be modulated ... -
Deciphering the regulation of tissue adaptation of regulatory T cells
Malko, Darya (2025-02-17)Regulatory T (Treg) cells are specialised immune cells of the CD4<sup>+</sup> T cell lineage that are indispensable for the maintenance of immune homeostasis and prevention of immune-mediated pathology. Most Treg cells ... -
Local synthesis of steroid hormones in human hair roots
Dorzweiler, Kristina (2025-02-17)Hair loss displays a common symptom with a multitude of different origins that complexes diagnostics and therapy. <br /> The basis of the current project was the hypothesis, that hair loss may be correlated or even ... -
Neurogenic Lower Urinary Tract Symptoms, Fatigue, and Depression — Are There Correlations in Persons with Multiple Sclerosis?
Jaekel, Anke Kirsten; Watzek, Julius; Nielsen, Jörn; Butscher, Anna-Lena; Zöhrer, Pirmin; Schmitz, Franziska; Kirschner-Hermanns, Ruth K. M.; Knüpfer, Stephanie C. (2023-08-04)The symptoms of multiple sclerosis (MS) frequently include fatigue, depression, and neurogenic lower urinary tract symptoms (LUTS), causing severe burdens on affected individuals. The relationships between these symptoms ... -
Fate mapping reveals compartment-specific clonal expansion of mononuclear phagocytes during kidney disease
Yin, Junping; Mei, Qi; Prinz, Marco; Abdullah, Zeinab; Panzer, Ulf; Li, Jian; von Vietinghoff, Sibylle; Kurts, Christian (2023-06-07) -
German GPs’ Self-Perceived Role in the COVID-19 Pandemic: Leadership, Participation in Regional Services and Preferences for Future Pandemic Preparedness
Kugai, Simon; Wild, Dorothea; Krumpholtz, Yelda; Schmidt, Manuela; Balzer, Katrin; Mayerböck, Astrid; Weltermann, Birgitta (2023-06-09)General practitioners (GPs) played a vital role during the COVID-19 pandemic. Little is known about GPs’ view of their role, leadership, participation in regional services and preferences for future pandemic preparedness. ... -
The role of primary cilia in controlling metaflammation
Picon Galindo, Ernesto (2025-02-14)The primary cilium is a cellular antenna that senses and integrates external stimuli. Its composition is regulated by specialized proteins, such as BBS proteins, and mutations in any of the genes that encode BBS proteins ...