Medizinische Fakultät: Medizinische Fakultät: Neuzugänge
Anzeige der Dokumente 81-100 von 2126
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Effect of the Height of a 3D-Printed Model on the Force Transmission and Thickness of Thermoformed Orthodontic Aligners
Ghoraba, Omar; Bourauel, Christoph; Aldesoki, Mostafa; Singer, Lamia; Ismail, Ahmed M.; Elattar, Hanaa; Alhotan, Abdulaziz; Elshazly, Tarek M. (2024-06-20)This research aims to investigate the influence of model height employed in the deep drawing of orthodontic aligner sheets on force transmission and aligner thickness. Forty aligner sheets (Zendura FLX) were thermoformed ... -
Retro Mode Imaging for Detection and Quantification of Sub-RPE Drusen and Subretinal Drusenoid Deposits in Age-Related Macular Degeneration
Saßmannshausen, Marlene; Sautbaeva, Leyla; Emde, Leon Alexander von der; Vaisband, Marc; Sloan, Kenneth R.; Hasenauer, Jan; Holz, Frank G.; Ach, Thomas (2024-07-15)<strong>Background:</strong> Drusen and drusenoid deposits are a hallmark of age-related macular degeneration (AMD). Nowadays, a multimodal retinal imaging approach enables the detection of these deposits. However, ... -
Diagnoses and Treatment Recommendations—Interrater Reliability of Uroflowmetry in People with Multiple Sclerosis
Jaekel, Anke Kirsten; Rieger, Julia; Butscher, Anna-Lena; Möhr, Sandra; Schindler, Oliver; Queissert, Fabian; Hofmann, Aybike; Schmidt, Paul; Kirschner-Hermanns, Ruth; Knüpfer, Stephanie C. (2024-07-18)Background: Uroflowmetry (UF) is an established procedure in urology and is recommended before further investigations of neurogenic lower urinary tract dysfunction (NLUTD). Some authors even consider using UF instead of ... -
The Phenotypic Correlates and Genetic Basis of the Central Neuroendocrine System
Xu, Peng (2025-07-29)The hypothalamus is considered the body’s principal center for maintaining homeostasis and orchestrating the secretion of multiple hormones. The pineal gland closely interacts with the hypothalamus and forms an essential ... -
Vergleich des Randschlussverhaltens von DeltaFil, einem neuartigen Glasionomerzement, mit herkömmlichen Restaurationsmaterialien in Klasse-II-Kavitäten: Eine in-vitro-Untersuchung nach künstlicher Alterung
Guyenz, Elena Maria (2025-07-29)Ziel dieser in-vitro-Studie war es, das Randspaltverhalten von DeltaFil, einem neu entwickelten Glasionomerzement der Firma DMG, im Vergleich zu herkömmlichen Restaurationsmaterialien in Klasse-II-Kavitäten zu untersuchen. ... -
Extracellular matrix substrates differentially influence enteric glial cell homeostasis and immune reactivity
Schneider, Linda; Schneider, Reiner; Hamza, Ebrahim; Wehner, Sven (2024-07-25)<strong>Introduction:</strong> Enteric glial cells are important players in the control of motility, intestinal barrier integrity and inflammation. During inflammation, they switch into a reactive phenotype enabling them ... -
In vitro extracellular replication of Wolbachia endobacteria
Behrmann, Lara Vanessa; Meier, Kirstin; Vollmer, Jennifer; Chiedu, Chukwuebuka Chibuzo; Schiefer, Andrea; Hoerauf, Achim; Pfarr, Kenneth (2024-07-18)Obligate intracellular endobacteria of the genus <em>Wolbachia</em> are widespread in arthropods and several filarial nematodes. Control programs for vector-borne diseases (dengue, Zika, malaria) and anti-filarial therapy ... -
Bidirectional Effect of Long-Term Δ9‑Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome
Bilkei-Gorzo, Andras; Schurmann, Britta; Schneider, Marion; Kraemer, Michael; Nidadavolu, Prakash; Beins, Eva C.; Müller, Christa E.; Dvir-Ginzberg, Mona; Zimmer, Andreas (2024-08-14)Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR) has a major impact on aging by regulating cellular metabolism. ... -
Assessment of local sensitivity in incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) lesions in intermediate age-related macular degeneration (iAMD)
Ameln, Julius; Saßmannshausen, Marlene; Emde, Leon von der; Carmichael-Martins, Alessandra; Holz, Frank G.; Ach, Thomas; Harmening, Wolf M. (2024-07-09)<strong>Objective</strong> Lesions of incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) are associated with disease progression in intermediate age-related macular degeneration (AMD). However, the ... -
Placental Sonomorphologic Appearance and Fetomaternal Outcome in Fontan Circulation
Jost, Elena; Gembruch, Ulrich; Schneider, Martin; Gieselmann, Andrea; La Rosée, Karl; Momcilovic, Diana; Vokuh, Christian; Kosian, Philipp; Ayub, Tiyasha H.; Merz, Waltraut M. (2024-09-01)<strong>Objectives:</strong> Pregnancies in women with Fontan circulation are on the rise, and they are known to imply high maternal and fetal complication rates. The altered hemodynamic profile of univentricular circulation ... -
The role of RER1 in the assembly and transport of TREM2-DAP12 complex and cellular lipid metabolism
Liu, Yanxia (2025-07-25)DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed on lymphoid and myeloid lineage cells, and interacts with several immune receptors to form functional complexes that trigger intracellular ... -
Modelling structure-function relationships from neurons to networks in the cerebral cortex
Fruengel, Rieke (2025-07-24)Using a multi-scale model based on extensive experimental data, I explored structure-function relationships in cortex. At a macro-scale, I used ANNs with cortical features to show that sparse connectivity enables efficient ... -
Targeting tumor cells with cytokine-induced killer cells and bifunctional peptides
Setiawan, Maria Fitria (2025-07-23)Antimicrobial peptides have gained much attention in clinical research due to their extensive possibilities of application beyond antimicrobial use. The modification of antimicrobial peptides enables the peptides to target ... -
Das Hitzeschockprotein GRP78 als Biomarker für Diagnose und Prognose bei Patienten mit Koronarer Herzerkrankung
Sommer-Weisel, Simon Ernst (2025-07-23)Das Hitzeschockprotein Glucose-regulated-protein-78 (GRP78) hat einen entscheidenden Einfluss auf die Homöostase im endoplasmatischen Retikulum und ist maßgeblich an der Antwort auf Stress des endoplasmatischen Retikulums ... -
Synthetic diets exacerbate auto-immunity in mice: EAE stage resolved proteomic immune cell characterization
Dernst, Alesja (2025-07-23)Western diet (WD)-associated non-communicable diseases (NCDs), including metabolic syndrome, and neurodegenerative conditions like multiple sclerosis (MS), are leading causes of death in the Western world. Although our ... -
Non-invasive physical plasma as an oncological therapy option: Modulation of cancer cell growth, motility, and metabolism without induction of cancer resistance factors
Wang, Yanqing (2025-07-23)<strong>Background:</strong> Physical plasma, the fourth state of matter formed through gas ionization, has shown promise in various clinical applications, including wound healing and antimicrobial therapy. Recently, ... -
The impact of the mesoprefrontal dopaminergic system on the maturation of interneurons in the murine prefrontal cortex
Islam, K. Ushna S.; Blaess, Sandra (2024-07-05)The prefrontal cortex (PFC) undergoes a protracted maturation process. This is true both for local interneurons and for innervation from midbrain dopaminergic (mDA) neurons. In the striatum, dopaminergic (DA) neurotransmission ... -
Demirjian's and Cameriere's Methods for the Assessment of Dental Age Estimation in Children from a Southern Brazilian City
Carelli, Julia; Sabrina da Silva, Gabriela; Vegini Gomes, Mariana; Vilalba, Thais; Baratto-Filho, Flares; Brancher, João Armando; Beisel-Memmert, Svenja; Kirschneck, Christian; Condeixa de França Lopes, Celia Maria; Moro, Alexandre; Calvano Küchler, Erika (2024-07-13)The chronological age estimation of living individuals is a crucial part of forensic practice and clinical practice, such as in orthodontic treatment. It is well-known that methods for age estimation in living children ... -
Long-term seizure outcome after epilepsy surgery of neuroglial tumors
Rácz, Attila; Müller, Philipp; Becker, Albert; Hoffmann, Nico; Rüber, Theodor; Borger, Valeri; Vatter, Hartmut; Surges, Rainer; Elger, Christian E. (2024-05-23)<strong>Purpose:</strong> Neuroglial tumors are frequently associated with pharmacorefractory epilepsies. However, comprehensive knowledge about long-term outcomes after epilepsy surgery and the main prognostic factors for ... -
Regenerative Parodontalchirurgie und kieferorthopädische Zahnbewegung bei Stadium IV Parodontitis: Ergebnisse klinischer Studien
Tietmann, Christina (2025-07-21)Parodontitis im Stadium IV ist charakterisiert durch schweren Verlust an parodontalem Attachment, vertikale Knochendefekte und pathologische Zahnwanderung (PTM). Die Komplexität des Krankheitsbildes aufgrund von PTM - ...