The Faculty of Medicine: Medizinische Fakultät: Recent submissions
Now showing items 61-80 of 2281
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Deep brain imaging of neuronal activity in sensory thalamus during innate and learned avoidance behavior
(2025-11-06)Avoidance behaviors are critical for survival, enabling organisms to respond effectively to potential threats in their environment. While much is known about how cortical and limbic brain areas contribute to avoidance ... -
Gingivaresektion mit Diodenlasern der Wellenlänge 445 nm und 970 nm: Auswertung der Pilotphase einer klinischen Vergleichsstudie
(2025-11-06)Im Rahmen einer Pilotstudie wurde ein 445 nm-Laser mit einem 970 nm-Laser als Testsystem für Gingivektomie-Maßnahmen verglichen. Insgesamt wurden 20 Zähne von acht Patienten behandelt. Der Untersuchungszeitraum erstreckte ... -
AI-Enhanced 3D Models in Global Virtual Reality Case Conferences for Surgical Care in a Low-Income Country: Exploratory Study
(2025-08-18)<strong>Background: </strong>Approximately 5 billion people worldwide lack adequate access to surgical care, primarily in the Global South. Especially in crisis regions and war zones, telemedical applications may enhance ... -
Drinking Water and Sanitation Safety Planning for Medical Facilities: An Innovative PoU Approach for a Water System Description Using Ecomaps
(2025-06-26)Drinking Water Safety Plans (DWSP) in buildings serve to identify health hazards associated with the drinking water system. Sanitation Safety Plans (SSP) fulfill the same purpose for the sewage system. Water Safety Plans ... -
Quantitative and qualitative tremor evaluation after MR-guided focused ultrasound thalamotomy
(2025-05-02)<strong>Introduction:</strong> Tremor syndromes are common neurological disorders, usually distinguished by clinical examination. Ordinal rating scales are widely used to rate tremor severity but are limited by subjective ... -
Neuropilin 2 in Osteoblasten
(2025-11-05)Neuropilin-2 (Nrp2) wird zunehmend als potenzielles therapeutisches Ziel bei Knochenmetastasen des kastrationsresistenten Prostatakarzinoms (CRPC) diskutiert. Es spielt eine Rolle in der Regulation der Osteogenese, doch ... -
In vitro Charakterisierung der antiproliferativen Wirksamkeit von nicht-invasivem physikalischem Plasma (NIPP: Non invasive physical plasma) in den drei gynäkologischen Malignitäten Leiomyosarkom (SK-UT-1), Mammakarzinom (MCF-7 und MDA-MB- 231) und Endometriumkarzinom (MFE-296)
(2025-11-03)Die bösartige Neoplasie der Brustdrüse ist die häufigste Todesursache bei Frauen zwischen dem 35. und 55. LJ. Das EC betrifft am häufigsten postmenopausale Frauen, um das Alter von 68 Jahren. Mit einer Inzidenz in Deutschland ... -
Kutane Nebenwirkungen und Supportivtherapie im Kontext der adjuvanten Bestrahlung des Mammakarzinoms
(2025-10-31)<strong>Hintergrund:</strong> Kutane Nebenwirkungen stellen die häufigste akute Nebenwirkung der adjuvanten Strahlentherapie beim Mammakarzinom dar. Akute Radiodermatitis betrifft bis zu 85 % der Patientinnen und kann ... -
A new generation of patient-reported outcome measures with large language models
(2025-03-24)<strong>Background</strong> Patient-reported outcome measures (PROMs) are cornerstones of patient-centered clinical medicine and reflect patients' abilities, difficulties, perceptions and behaviors. The highly structured ... -
Fibroblast growth factor receptor 2 (FGFR2) genetic polymorphisms contribute to fused roots in human molars
(2025-04-10)Fibroblast growth factors (FGFRs) signaling are required for human tooth development. Its dysregulation affects tooth formation and patients with <em>FGFR2</em> mutations often present dental anomalies in the spectrum of ... -
Alterations in dopaminergic innervation and receptors in focal cortical dysplasia
(2025-04-16)Focal cortical dysplasia (FCD) type 2 is the most common malformation of cortical development associated with pharmaco-resistant focal epilepsy and frequently located in the frontal cortex. Neuropathological hallmarks ... -
The PJI-TNM Classification as Predictor for Revision-Free Implant Survival Rates in Patients with Periprosthetic Joint Infection of the Hip or Knee Joint
(2025-05-15)Background: Periprosthetic joint infections (PJIs) remain a major challenge in arthroplasty. This study tries to evaluate the PJI-TNM classification as predictor for the revision-free implant survival in patients with PJI ... -
Quality Management Outweighs Pandemic: Retrospective Analysis Shows Improved Quality of Care for Staphylococcus aureus Bacteremia Despite SARS-CoV-2
(2025-03-30)Background: <em>Staphylococcus aureus</em> bacteremia (SAB) is of great clinical relevance, as it is the most common type of bacteremia. Several studies show that the quality of care and thus the outcome can be positively ... -
Intraoperative Profiling of the Supracrestal Implant Complex Minimizes Peri-Implant Crestal Bone Remodeling: The Guided Bone Profiling Concept
(2025-03-08)(1) Background: Early-stage bone resorption following implant placement can significantly impact the long-term success of implants. This study evaluates whether a fully digitally planned implant position based on the E-point ... -
Robust COVID-19 Vaccine Responses Despite Filarial Co-Infection: Insights from a Lymphatic Filariasis Cohort in Ghana
(2025-03-13)Background/Objectives: Although the COVID-19 pandemic has largely concluded, the varied trajectories it has followed in different regions of the world remain incompletely understood. Intensive research is needed to fully ... -
Optogenetic quantification of cardiac excitability and electrical coupling in intact hearts to explain cardiac arrhythmia initiation
(2025-02-28)Increased cardiac excitability and reduced electrical coupling promote cardiac arrhythmia and can be quantified by input resistance (<em>R<sub>m</sub></em>), pacing threshold (<em>I<sub>thr</sub></em>), and cardiac space ... -
Psychological safety, job satisfaction, and the intention to leave among German early-career physicians
(2025-01-17)<strong>Background</strong> Healthcare systems worldwide experience shortages of healthcare professionals. Retention of physicians is becoming an increasing problem. The psychological safety among physicians affects not ... -
Trajectories of Mental Distress and Resilience During the COVID-19 Pandemic Among Healthcare Workers
(2025-03-06)<strong>Background/Objectives:</strong> The recent COVID-19 pandemic posed a significant psychological challenge for healthcare workers. Resilience and the extent of psychological stress varied across professional groups ... -
Retrospektive Analyse nativer Kniegelenksinfektionen: Einfluss klinischer, mikrobiologischer und laborchemischer Faktoren auf den klinischen Verlauf und Therapieerfolg
(2025-10-24)Die Inzidenz des nativen Kniegelenkinfekts steigt in den letzten Jahren stetig ein. Eine schnelle Diagnosesicherung ist notwendig, um schwerwiegende Gelenkdestruktionen, Funktionseinschränkungen oder auch eine Sepsis zu ...
