The Faculty of Medicine: Medizinische Fakultät: Recent submissions
Now showing items 61-80 of 2126
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Mind wandering, poor sleep, and negative affect: a threefold vicious cycle?
(2024-09-05)Mind wandering (MW) is intricately linked to sleep and affect, bearing clinical relevance for various psychiatric conditions, notably attention deficit/hyperactivity disorder, depression, and anxiety disorders. Most reviews ... -
Brain and Ventricle Volume Alterations in Idiopathic Normal Pressure Hydrocephalus Determined by Artificial Intelligence-Based MRI Volumetry
(2024-07-03)The aim of this study was to employ artificial intelligence (AI)-based magnetic resonance imaging (MRI) brain volumetry to potentially distinguish between idiopathic normal pressure hydrocephalus (iNPH), Alzheimer's disease ... -
Comorbidity profiles among sputum-positive tuberculosis patients in Cameroon
(2024-10-02)<strong>Introduction:</strong> Comorbid non-communicable diseases (NCDs) like diabetes, cardiovascular diseases (CVD), kidney diseases, and hypertension, could have implications for tuberculosis (TB) treatment management ... -
Innovative Regional Services and Heterogeneous Communication Channels: Results from the Nationwide German egePan Project for Pandemic Management
(2024-11-04)<strong>Background:</strong> In the COVID-19 pandemic, novel regional services and communication channels emerged across all sectors of the German healthcare system. To contribute to pandemic preparedness, this study aims ... -
Expressionsmodulation der Hitzeschockproteine HSP27 und HSP70 in malignen Zellen nach Exposition gegenüber nicht-invasivem physikalischem Plasma
(2025-08-05)Aufgrund seines vor allem wachstumshemmenden Effekts auf maligne Zellen gilt Nicht-invasives physikalisches Plasma (NIPP) als vielversprechende Therapieoption in der Onkologie. <br/> Aktuelle Studien konnten eine Beteiligung ... -
Reproduzierbarkeit der quantitativen Auswertung der PSMA-PET
(2025-08-05)<strong>Hintergrund:</strong> Bei Patienten mit Prostatakarzinom, die eine PSMA-gerichtete Radioligandentherapie (RLT) erhalten, korrelieren höhere SUV-Werte mit besseren Therapieergebnissen. Daher ist es entscheidend, die ... -
Investigation and discovery of targetable markers in urological tumors
(2025-08-05)Urological cancers are among the cancers with the highest incidence. In recent years, several therapeutic solutions have been suggested and accepted in the clinic for treatment, but tumors, especially the most aggressive ... -
AIM2-Inhibitory Nanobodies Reveal Differential Activation of AIM2 and NLRP3 Inflammasomes by Poxvirus DNA Genomes in Primary Human Cells
(2025-08-05)Poxviruses are large double-stranded (ds)DNA viruses that replicate in the cytoplasm. While variola virus (VARV) caused millions of deaths before its eradication in 1980, monkeypox virus (MPXV) has been declared a public ... -
New perspectives on semi-parametric and pseudo-value approaches for modeling clinical time-to-event data
(2025-08-04)Clinical decision-making often relies on quantitative measures derived from statistical time-to-event models, enabling risk assessment through the quantification of survival probabilities. A key goal of these modeling ... -
Anfall und Epilepsie: Morphometrische Kurz- und Langzeitkorrelate im mesialen Temporallappen
(2025-08-04)Epilepsie zählt zu den häufigsten chronischen neurologischen Erkrankungen, wobei die mesiale Temporallappenepilepsie (mTLE) die häufigste Form therapieresistenter Anfälle bei Erwachsenen darstellt. Die häufigste ... -
Evaluating Bard Gemini Pro and GPT-4 Vision Against Student Performance in Medical Visual Question Answering: Comparative Case Study
(2024-12-17)<strong>Background:</strong> The rapid development of large language models (LLMs) such as OpenAI's ChatGPT has significantly impacted medical research and education. These models have shown potential in fields ranging ... -
Efficacy of Virtual Preparation Simulators Compared to Traditional Preparations on Phantom Heads
(2024-08-14)Background: Virtual simulators are increasingly being introduced in dental education. This study investigates whether virtual simulators offer comparable or superior educational efficacy when compared to traditional phantom ... -
Associations Between Clinical Factors and Postoperative Thrombosis in Pediatric Cardiac Surgery Patients: A Single-Center Retrospective Study
(2024-10-21)<strong>IMPORTANCE:</strong> Postoperative thrombosis is a significant complication in pediatric cardiac surgery patients, contributing to morbidity and mortality. Identifying clinical factors associated with thrombosis ... -
Schistosomiasis endemicity and its role in sexually transmitted infections: A systematic review and meta-analysis
(2024-09-02)<strong>Introduction:</strong> Schistosomiasis, a tropical parasitic disease, affects 779 million people globally, with 85% of cases in Africa. The interplay between schistosomiasis and other sexually transmitted infections ... -
Therapeutic alliance in individual adult psychotherapy: A systematic review of conceptualizations and measures for face-to-face- and online-psychotherapy
(2024-06-27)<strong>Background:</strong> The therapeutic alliance (TA) is a robust and pantheoretical predictor of treatment outcome in Face-to-Face- (F2F-) and Online-psychotherapy (Online-PT). Many authors have proposed several ... -
Auswirkung der Lagerungsdauer von Erythrozytenkonzentraten auf den Anstieg der Hämoglobin-Konzentration nach Transfusion: Eine Subgruppen-Analyse der LIBERAL-Studie
(2025-08-01)Die LIBERAL-Studie ist eine DFG geförderte, prospektive, randomisierte, multizentrische, kontrollierte, klinische Phase-IV-Studie, an der 2.470 ältere Patienten teilnehmen, die sich einer nicht-herzchirurgischen Operation ... -
Investigating the Role of Descending Neurons in Freely Flying Drosophila melanogaster
(2025-08-01)Understanding how neural circuits generate complex behaviors remains a central challenge in neuroscience. This thesis investigates the neural basis of flight control in <em>Drosophila melanogaster</em>, focusing on how ... -
Prädiktoren für eine behandlungsbedürftige Koronarstenose nach einer ventrikulären Arrhythmie bei Patienten mit Implantierbarem Kardioverter-Defibrillator (ICD)
(2025-08-01)In dieser retrospektiven Studie wurden 183 ICD-Patienten untersucht, die nach einer ventrikulären Arrhythmie (VA) eine Koronarangiographie erhielten. Ziel war es, Prädiktoren für das Vorliegen einer behandlungsbedürftigen ... -
Neuroprotective Role and Immunomodulatory Effects of Sialylation
(2025-07-29)Sialic acids are terminal sugars on the cellular glycocalyx, crucial for modulating immune responses in the sialylated central nervous system. Sialylation acts as an inhibitory checkpoint, regulating inflammation and tissue ... -
Force system of 3D-printed orthodontic aligners made of shape memory polymers: An in vitro study
(2024-06-10)This study aimed to report forces and moments delivered by 3D-printed aligners. Tera Harz TC-85 resin and Zendura FLX (ZF) thermoformed sheets (0.76 mm) were used. Rectangular strip specimens (50 × 10 × 0.6 mm) were produced ...
