Medizinische Fakultät: Medizinische Fakultät: Neuzugänge
Anzeige der Dokumente 41-60 von 2126
-
Epidemiology and outcomes of vancomycin-resistant enterococcus infections: A systematic review and meta-analysis
Eichel, Vanessa M.; Last, Katharina; Brühwasser, Christina; Baum, Heike von; Dettenkofer, Markus; Götting, Tim; Grundmann, Hajo; Güldenhöven, Hanna; Liese, Jan; Martin, Maria; Papan, Cihan; Sadaghiani, Catharina; Wendt, Constanze; Werner, Guido; Mutters, Nico (2023-09-19)Vancomycin-resistant enterococci (VRE) cause many infections in the healthcare context. Knowledge regarding the epidemiology and burden of VRE infections, however, remains fragmented. We aimed to summarize recent studies ... -
Evaluating AI Courses: A Valid and Reliable Instrument for Assessing Artificial-Intelligence Learning through Comparative Self-Assessment
Laupichler, Matthias Carl; Aster, Alexandra; Perschewski, Jan-Ole; Schleiss, Johannes (2023-09-26)A growing number of courses seek to increase the basic artificial-intelligence skills ("AI literacy") of their participants. At this time, there is no valid and reliable measurement tool that can be used to assess AI-learning ... -
Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years
Saßmannshausen, Marlene; Döngelci, Senem; Vaisband, Marc; Emde, Leon von der; Sloan, Kenneth R.; Hasenauer, Jan; Holz, Frank G.; Schmitz-Valckenberg, Steffen; Ach, Thomas (2024-04-30)<strong>PURPOSE.</strong> To longitudinally assess the impact of high-risk structural biomarkers for natural disease progression in non-exudative age-related macular degeneration (AMD) on spatially resolved mesopic and ... -
Key factors for sustainable working conditions in emergency departments: An EUSEM-initiated, Europe-wide consensus survey
Weigl, Matthias; Lifschitz, Michael; Dodt, Christoph (2025-02)<em>Background and importance</em> Modern emergency medicine (EM) is a complex, demanding, and occasionally stressful field of work. Working conditions, provider well-being, and associated health and performance outcomes ... -
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function
Khani, Sajjad; Topel, Hande; Kardinal, Ronja; Tavanez, Ana Rita; Josephrajan, Ajeetha; Larsen, Bjørk Ditlev Marcher; Gaudry, Michael James; Leyendecker, Philipp; Meincke Egedal, Nadia; Güller, Aylin Seren; Stanic, Natasa; Ruppert, Phillip M. M.; Gaziano, Isabella; Hansmeier, Nils Rouven; Schmidt, Elena; Klemm, Paul; Vagliano, Lara-Marie; Stahl, Rainer; Duthie, Fraser; Krause, Jens-Henning; Bici, Ana; Engelhard, Christoph Andreas; Gohlke, Sabrina; Frommolt, Peter; Gnad, Thorsten; Rada-Iglesias, Alvaro; Pradas-Juni, Marta; Schulz, Tim Julius; Wunderlich, Frank Thomas; Pfeifer, Alexander; Bartelt, Alexander; Jastroch, Martin; Wachten, Dagmar; Kornfeld, Jan-Wilhelm (2024-04-29)Promoting brown adipose tissue (BAT) activity innovatively targetsobesity and metabolic disease. While thermogenic activation of BAT is wellunderstood, the rheostatic regulation of BAT to avoid excessive energy dissipation ... -
The Spectrum of Functional, Structural and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report
Terheyden, Jan Henrik; Holz, Frank G.; Behning, Charlotte; Dunbar, Hannah M.P.; Schmitz-Valckenberg, Steffen; Tufail, Adnan; Schmid, Matthias; Crabb, David P.; Saßmannshausen, Marlene; Binns, Alison; Hoyng, Carel B.; Zakaria, Nadia; Poor, Stephen; Moll, Klaus-Peter; Cosette, Deborah; Martinho, Cecília; Batuca, Joana; Cunha-Vaz, José; Luhmann, Ulrich F.O.; Leal, Sergio; Finger, Robert P. (2025-02-03)<em><strong>Introduction:</strong></em> There is an unmet medical need for therapies in intermediate age-related macular degeneration (iAMD). The prospective European multi-center cohort study MACUSTAR validates structural, ... -
TFAP2E is implicated in central nervous system, orofacial and maxillofacial anomalies
Kalanithy, Jeshurun C.; Mingardo, Enrico; Stegmann, Jil D.; Dhakar, Ramgopal; Dakal, Tikam Chand; Rosenfeld, Jill A.; Tan, Wen-Hann; Coury, Stephanie A.; Woerner, Audrey C.; Sebastian, Jessica; Levy, Paul A.; Fleming, Leah R.; Waffenschmidt, Lea; Lindenberg, Tobias T.; Yilmaz, Öznur; Channab, Khadija; Babra, Bimaljeet K.; Christ, Andrea; Eiberger, Britta; Hölzel, Selina; Vidic, Clara; Häberlein, Felix; Ishorst, Nina; Rodriguez-Gatica, Juan E.; Pezeshkpoor, Behnaz; Kupczyk, Patrick A.; Vanakker, Olivier M.; Loddo, Sara; Novelli, Antonio; Dentici, Maria L.; Becker, Albert; Thiele, Holger; Posey, Jennifer E.; Lupski, James R.; Hilger, Alina C.; Reutter, Heiko M.; Merz, Waltraut M.; Dworschak, Gabriel C.; Odermatt, Benjamin (2024-12-23)<strong>Background</strong> Previous studies in mouse, <em>Xenopus</em> and zebrafish embryos show strong <em>tfap2e</em> expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in ... -
Ergebnisse von abdomino-thorakalen Eingriffen am Lymphgefäßsystem zur Behandlung traumatischer und nicht-traumatischer Lymphleckagen
Kaminski, Lea Caterina (2025-08-11)<strong>Hintergrund:</strong><br /> Chylöse Ergüsse wie Chylothorax oder Chylaszites stellen seltene, aber schwerwiegende Krankheitsbilder dar, die häufig mit hoher Morbidität und Mortalität einhergehen. Ziel dieser Studie ... -
Across Diagnostic Boundaries: Genetic Variants for Neuropsychiatric Disorders and their Association with Human Brain Structure
Federmann, Lydia Marie (2025-08-11)With the advances in genome-wide association studies (GWAS), hundreds of genetic variants have been identified for neuropsychiatric disorders. Strikingly, many of these genetic variants showed complex associations across ... -
NIS-Seq enables cell-type-agnostic optical perturbation screening
Fandrey, Caroline I.; Jentzsch, Marius; Konopka, Peter; Hoch, Alexander; Blumenstock, Katja; Zackria, Afraa; Maasewerd, Salie; Lovotti, Marta; Lapp, Dorothee J.; Gohr, Florian N.; Suwara, Piotr; Świeżewski, Jędrzej; Rossnagel, Lukas; Gobs, Fabienne; Cristodaro, Maia; Muhandes, Lina; Behrendt, Rayk; Lam, Martin C.; Walgenbach, Klaus J.; Bald, Tobias; Schmidt, Florian I.; Latz, Eicke; Schmid-Burg, Jonathan L. (2024-12-19)Optical pooled screening offers a broader-scale alternative to enrichment-based perturbation screening, using fluorescence microscopy to correlate phenotypes and perturbations across single cells. Previous methods work ... -
Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei
Kien, Chi Anizette; Ebai, Rene; Fombad, Fanny Fri; Esofi, Frederick; Ntuh, Anna Ning; Ouam, Emmanuel; Gandjui, Narcisse Victor Tchamatchoua; Chunda, Valerine Chawa; Ekanya, Relindis; Nietcho, Franck Noel; Foyet, Juluis Visnel; Nchang, Lucy Cho; Magha, Chefor; Njouendou, Abdel Jelil; Enyong, Peter; Hoerauf, Achim; Ritter, Manuel; Wanji, Samuel (2024-12-10)<strong>Background:</strong> <em>Mansonella perstans</em> is transmitted by <em>Culicoides</em> species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis ... -
Comparative Analysis of Shear Bond Strength in Orthodontic Brackets Between Milled and 3D-Printed Definitive CAD/CAM Restorations
Aldosari, Mohammad A.; Anany, Noha M.; Alaqeely, Razan; Alsenaidi, Jawaher; Sufyan, Aref; Talaat, Sameh; Bourauel, Christoph; Elshazly, Tarek M.; Alhotan, Abdulaziz (2024-10-18)<strong>Objective:</strong> The objective of this study was to evaluate the effect of different surface treatment methods on the shear bond strength (SBS) of metal brackets bonded to two types of CAD/CAM composite restorations: ... -
Schistosomiasis–Microbiota Interactions: A Systematic Review and Meta-Analysis
Afful, Philip; Abotsi, Godwin Kwami; Adu-Gyamfi, Czarina Owusua; Benyem, George; Katawa, Gnatoulma; Kyei, Samuel; Arndts, Kathrin; Ritter, Manuel; Asare, Kwame Kumi (2024-10-16)Introduction: Schistosomiasis, a tropical disease affecting humans and animals, affected 251.4 million people in 2021. <em>Schistosoma mansoni, S. haematobium, S. intercalatum</em>, and <em>S. japonicum</em> are primary ... -
Entwicklung und Validierung eines Screeninginstrumentes zur Diagnose einer Sepsis nach Schlaganfall
Kleusch, Lisa (2025-08-08)Schlaganfall-assoziierte Infektionen können eine Sepsis hervorrufen, die mit einem schlechten klinischen Outcome assoziiert ist. Die lebensbedrohliche Organdysfunktion, welche die Sepsis definiert, kann mittels Sequential ... -
Single-neuron representations of odours in the human brain
Kehl, Marcel S.; Mackay, Sina; Ohla, Kathrin; Schneider, Matthias; Borger, Valeri; Surges, Rainer; Spehr, Marc; Mormann, Florian (2024-10-09)Olfaction is a fundamental sensory modality that guides animal and human behaviour. However, the underlying neural processes of human olfaction are still poorly understood at the fundamental—that is, the single-neuron—level. ... -
Mikrobielle Kontamination auf temporären Herzschrittmacher-Elektroden nach Transkatheter-Aortenklappen-Implantation und deren Einfluss auf klinischen Verlauf
Mousa Basha, Mustafa (2025-08-08)Hintergrund und Zielsetzung: <br/> Die Transkatheter-Aortenklappenimplantation (TAVI) ist eine etablierte Behandlungsoption für Patienten mit symptomatischer, hochgradiger Aortenklappenstenose – unabhängig vom chirurgischen ... -
Microbial Spectrum, Intraoperative Findings, and Postoperative Outcomes in Native Knee Joint Infections: A Retrospective Analysis
Roos, Jonas; Mangels, Britta; Jaenisch, Max; Wimmer, Matthias Dominik; Randau, Thomas Martin; Prangenberg, Christian; Welle, Kristian; Gathen, Martin (2024-12-16)<strong>Background:</strong> Native knee joint infections, while uncommon, present a serious condition predominantly instigated by bacteria such as <em>Staphylococcus aureus</em>. Without timely intervention, they can ... -
From Language Models to Medical Diagnoses: Assessing the Potential of GPT-4 and GPT-3.5-Turbo in Digital Health
Roos, Jonas; Wilhelm, Theresa Isabelle; Martin, Ron; Kaczmarczyk, Robert (2024-12-02)Background: Large language models (LLMs) like GPT-3.5-Turbo and GPT-4 show potential to transform medical diagnostics through their linguistic and analytical capabilities. This study evaluates their diagnostic proficiency ... -
Characterization of the disorganization of the inner retinal layers in diabetics using increased axial resolution optical coherence tomography
Wall, Katharina; Arend, Lilith P.; Emde, Leon von der; Saßmannshausen, Marlene; Holz, Frank G.; Ach, Thomas (2025-01-13)<strong>Purpose:</strong> To compare a novel high-resolution optical coherence tomography (OCT) with improved axial resolution (High-Res OCT) with conventional spectral-domain OCT (SD-OCT) with regard to their capacity to ... -
Barriers and Facilitators of Patient Engagement Activities to Improve Patient Safety in Healthcare Organizations: A Delphi-Based Expert Survey
Koch, Amelie; Brust, Larissa; Weigl, Matthias (2024-12-19)<strong>Purpose:</strong> In order to obtain sustainable healthcare, engagement of patients in patient safety improvement is vital. Drawing upon a multi-perspective approach, this study aimed to investigate perspectives ...