E-Dissertationen: Search
Now showing items 11-20 of 218
The bromodomain inhibitor JQ1 as novel therapeutic option for type II testicular germ cell tumours [and] The role of SOX2 and SOX17 in regulating germ cell tumour pluripotency
(2019-08-01)
The bromodomain inhibitor JQ1 as novel therapeutic option for type II testicular germ cell tumours
Type II testicular germ cell tumours (TGCTs) represent the most common malignancy in young men (19-35 ...
Type II testicular germ cell tumours (TGCTs) represent the most common malignancy in young men (19-35 ...
Migration component dynamics in epithelial cell motility
(2019-08-05)
Cell migration is a fundamental process in development and maintenance of multicellular organisms. Harmonious cellular movement is coordinated by finely tuned assembly and release of cell-substrate attachment sites. ...
Pulsar Searching and Timing with the Arecibo and Effelsberg Radio Telescopes
(2019-08-13)
Pulsars are rapidly rotating, highly magnetized, neutron star remnants of the supernova explosions of massive stars. In this thesis, I mostly focus on recycled pulsars, which are old (approx 100 million years old) neutron ...
Three-pion dynamics at COMPASS: resonances, rescattering and non-resonant processes
(2019-12-13)
This thesis presents studies of the strong interaction in the non-perturbative regime by analyzing the properties of hadronic resonances. The basis for this research is the world's largest dataset on diffractive reactions, ...
Search for the Standard Model Higgs boson pair production and new physics phenomena in the bb τ+hadτ-had final state with the ATLAS detector
(2019-12-12)
A search for the Standard Model (SM) Higgs boson pair production and new physics phenomena in the $bbar{b}tau_{had}^+ tau_{had}^-$ final state is presented. The search uses $SI{36.1}{fb^{-1}}$ of $pp$ collisions data at a ...
Numerical Methods for Optimal Transport and Elastic Shape Optimization
(2019-12-06)
In this thesis, we consider a novel unbalanced optimal transport model incorporating singular sources, we develop a numerical computation scheme for an optimal transport distance on graphs, we propose a simultaneous elastic ...
Generation and Applications of Knowledge Graphs in Systems and Networks Biology
(2019-12-16)
The acceleration in the generation of data in the biomedical domain has necessitated the use of computational approaches to assist in its interpretation. However, these approaches rely on the availability of high quality, ...
Fast diffusion MRI based on sparse acquisition and reconstruction for long-term population imaging
(2019-11-21)
Diffusion weighted magnetic resonance imaging (dMRI) is a unique MRI modality to probe the diffusive molecular transport in biological tissue. Due to its noninvasiveness and its ability to investigate the living human brain ...
Untersuchungen zur Radionuklidbereitstellung von Fluor-18 für die Synthese von 18F-markierten PET-Tracern mit Hilfe von automatisierter fluider Synthesetechnik
(2019-12-16)
Für die Diagnostik von Stoffwechselerkrankungen wird die Positronenemissionstomographie (PET) unter Einsatz von spezifischen 18F Radiopharmaka genutzt. Neben etablierten Radiopharmaka wie beispielsweise ...
Computational Analysis of Pathophysiological Mechanisms Based on Pathway Modeling
(2019-12-18)
The advent of the big data era poses major challenges to the biomedical domain. First, it is necessary to adopt strategies that integrate and link the heterogeneous resources that contain multiscale and multimodal data in ...